1.Endoscopic Removal of Upper Gastrointestinal Tract Foreign Body.
Woo Joong KIM ; Myung Seok LEE
Korean Journal of Gastrointestinal Endoscopy 1992;12(2):227-230
The clinical review was done on 17 cases with the foreign body in the upper gastrointestinal tract who underwent endoscopic removal of foreign body at Kang Nam Sacred Heart Hospital from Dec. 1981 to Dec. 1991. The results were as follows: 1) The age distribution varies from 3 months to 72 years of age, being most prevalent under 5 years of age. 2) The incidence of foreign body in the order of frequency was coin, fish bone, safety pinring, peanut, keyring, food bolus, artificial teeth and medal. Among 17 cases, 9 cases(53.0%) were lodged in the esophagus and 8 cases(47.0%) were lodged in the stomach. 3) Dysphagia or globus was the common symptom in 8 cases(47.2%), followed by absence of symptom in 7 cases(41.2%), upper abdominal discomfort in 1 case(5.8%) and vomiting in 1 case (5.8%). 4) l0 cases(58.8%) of foreign body were removed within 72 hours and 7 cases(41.2%) of foreign body were removed after 72 hours.
Age Distribution
;
Deglutition Disorders
;
Esophagus
;
Foreign Bodies*
;
Heart
;
Incidence
;
Numismatics
;
Stomach
;
Tooth, Artificial
;
Upper Gastrointestinal Tract*
;
Vomiting
2.Experimental study on the effect of heat treatment on the orthodontic wires.
Myung Seok LEE ; Byung Wha SOHN
Korean Journal of Orthodontics 1992;22(3):591-601
No abstract available.
Hot Temperature*
;
Orthodontic Wires*
3.Adenomyoma of the small intestine: a rare cause of intussusception in an infant.
Hee Soo LEE ; Tae Seok LEE ; Soo Myung OH
Journal of the Korean Surgical Society 1992;42(5):717-721
No abstract available.
Adenomyoma*
;
Humans
;
Infant*
;
Intestine, Small*
;
Intussusception*
4.Effects of Reactive Oxygen Metabolite on the Calcium Transport of Cardiac Mitochondria.
Myung Suk KIM ; Yun Song LEE ; Seok Chan HONG
Korean Circulation Journal 1994;24(1):145-155
BACKGROUND: Intracellular calcium overload is a common final feature of the ischemic-reperfused heart and mediates the genesis of irreversible cell damage. Reactive oxygen medabolites have been known to play and important role as toxic mediators in myocardial injuries resulting from ischemia and reperfusion. In order to investigate the mechanism of intracellular calcium accumulation in the ischemic-reperfused myocardium, the present study observed the possible contribution of the reactive oxygen metabolite to the calcium transport of cardiac mitochondria. METHODS: Mitochondrial were isolated from rabbit hearts. The effects of a reactive oxygen metabolite, H2O2 on calcium uptake and release, redox states of endogenous pyridine nucleotides and glutathiones of mitochondria respiring with succinate were observed. Calcium uptake and release were monitored by dual-wave length spectrophotometer using a calcium indicator, arsenaze III. Contents and redox states of pyridine nucleotides and glutathiones were measured by enzymatic methods using spectrofluorometer and HPLC. RESULTS: Hydrogen peroxide(10-500microM) promoted calcium release dose-dependently from CA++-preloaded mitochondria, but did not affect the mitochondrial calcium uptake. The H2O2-induced calcium release was accompanied by simultaneous oxidation of the pyridine nucleotides and decrease in the content of the reduced form of glutathione(GSH). When mitochondria were treated with BCNU(N,N=bis(2-chloroethyl)-N-nitrosourea) to inhibit glutathione reductase and so as to reduce the GSH content, there were no increase in calcium release from the mitochondria. These results may indicate that H2O2 increases the permeability of cardiac mitochondrial membrane to calcium in association with the changes in redox state of endogenous pyridine nucleotides, but not with that of glutathiones. CONCLUSION: It is suggested that the reactive oxygen metabolites induce the release of calcium from mitochondria by altering the redox state of pyridine nucleotides, and it may partly be involved in the elevation of cytosolic calcium concentration in the ischemic-reperfused myocardial cells.
Calcium*
;
Chromatography, High Pressure Liquid
;
Cytosol
;
Glutathione Reductase
;
Heart
;
Hydrogen
;
Ischemia
;
Mitochondria*
;
Mitochondrial Membranes
;
Myocardium
;
Nucleotides
;
Oxidation-Reduction
;
Oxygen*
;
Permeability
;
Reperfusion
;
Succinic Acid
5.Susceptibility to Antivirals of a Human HBV Strain with Mutations Conferring Resistance to Both Lamivudine and Adefovi.
Yun Jung CHANG ; Myung Seok LEE
The Korean Journal of Gastroenterology 2005;46(4):316-317
No abstract availble
6.A Case of Salmonella Meningitis.
Oh Kyung LEE ; Seok Ku KIM ; Chul LEE ; Myung Ho LEE
Journal of the Korean Pediatric Society 1982;25(12):1270-1274
No abstract available.
Meningitis*
;
Salmonella*
7.Crossed Cerebellar Hyperperfusion on Ictal Tc-99m HMPAO Brain SPECT: Clinical Significance for Differentiation of Mesial or Lateral Temporal Lobe Epilepsy and Related Factors for Development.
Dong Soo LEE ; June Key CHUNG ; Myung Chul LEE ; Soon Ah PARK ; Seok Ki KIM ; Sang Gun LEE ; Myoung Jin JANG ; Myung Hee SOHN ; Seok Tae LIM
Korean Journal of Nuclear Medicine 2000;34(4):312-321
PURPOSE: The aim of this study was to determine whether crossed cerebellar hyperperfusion (CCH) was helpful in discriminating mesial from lateral temporal lobe epilepsy (TLE) and what other factors were related in the development of CCH on ictal brain SPECT. MATERALS AND METHODS: We conducted retrospective analysis in 59 patients with TLE (M:41, F:18; 27.4+/-7.8 years old; mesial TLE: 51, lateral TLE: 8), which was confirmed by invasive EEG and surgical outcome (Engel class I , II). All the patients underwent ictal Tc-99m HMPAO brain SPECT and their injection time from ictal EEG onset on video EEG monitoring ranged from 11 sec to 75 sec (32.6+/-19.5 sec) in 39 patients. Multiple factors including age, TLE subtype (mesial TLE or lateral TLE), propagation pattern (hyperperfusion localized to temporal lobes, spread to adjacent lobes or contralateral hemisphere) and injection time were evaluated for their relationship with CCH using multiple logistic regression analysis RESULTS: CCH was observed in 18 among 59 patients. CCH developed in 29% (15/51) of mesial TLE patients and 38% (3/8) of lateral TLE patients. CCH was associated with propagation pattern; no CCH (0/13) in patients with hyperperfusion localized to temporal lobe, 30% (7/23) in patients with propagation to adjacent lobes, 48% (11/23) to contralateral hemisphere. Multiple logistic regression analysis revealed that propagation pattern (p=0.01) and age (p=0.02) were related to the development of CCH. CONCLUSION: Crossed cerebellar hyperperfusio ictal brain SPECT did not help differentiate mesial from lateral temporal lobe epilepsy. Crossed cerebellar hyperperfusion was associated with propagation pattern of temporal lobe epilepsy and age.
Brain*
;
Electroencephalography
;
Epilepsy
;
Epilepsy, Temporal Lobe*
;
Humans
;
Logistic Models
;
Retrospective Studies
;
Technetium Tc 99m Exametazime*
;
Temporal Lobe*
;
Tomography, Emission-Computed, Single-Photon*
8.Can the C-14 Urea Breath Test Reflect the Extent and Degree of Ongoing Helicobacter pylori Infection?.
Seok Tae LIM ; Myung Hee SOHN ; Seung Ok LEE ; Soo Teik LEE ; Myoung Ja JEONG
Korean Journal of Nuclear Medicine 2001;35(1):61-68
PURPOSE: The C-14 urea breath test (C-14 UBT) is the most specific noninvasive method to detect Helicobacter (H) pylori infection. We investigated if the C-14 UBT can reflect the presence and degree of H. pylori detected by gastroduodenoscopic biopsies (GBx). MATERIALS AND METHODS: One hundred fifty patients (M:F=83:67, age 48.6+/-11.2 yrs) underwent C-14 UBT, rapid urease test (CLO test) and GBx on the same day. For the C-14 UBT, a single breath sample was collected at 10 minutes after ingestion of C-14 urea (137 KBq) capsule and counting was done in a liquid scintillation counter for 1 minute, and the results were classified as positive ( 200 dpm), intermediate (50~199 dpm) or negative (<50 dpm). The results of CLO tests were classified as positive or negative according to color change. The results of GBx on giemsa stain were graded 0 (normal) to 4 (diffuse) according to the distribution of H. pylori by the Wyatt method. We compared C-14 UBT results with GBx grade as a gold standard. RESULTS: In the assessment of the presence of H. pylori infection, the C-14 UBT global performance yielded sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) and accuracy of 92.5%, 88.4%, 97.1%, 88.4% and 91.3%, respectively. However, the CLO test had sensitivity, specificity, PPV, NPV and accuracy of 83.2%, 81.4%, 91.8%, 81.4% and 82.7%, respectively. The quantitative values of the C-14 UBT were 45+/-27 dpm in grade 0, 707+/-584 dpm in grade 1, 1558+/-584 dpm in grade 2, 1851+/-604 dpm in grade 3, and 2719+/-892 dpm in grade 4. A significant correlation (r=0.848, p<0.01) was found between C-14 UBT and the grade of distribution of H. pylori infection on GBx with giemsa stain. CONCLUSION: We conclude that the C-14 UBT is a highly accurate, simple and noninvasive method for the diagnosis of ongoing H. pylori infection and reflects the degree of bacterial distribution.
Azure Stains
;
Biopsy
;
Breath Tests*
;
Diagnosis
;
Eating
;
Helicobacter pylori*
;
Helicobacter*
;
Humans
;
Scintillation Counting
;
Sensitivity and Specificity
;
Urea*
;
Urease
9.The Usefulness of Myocardial SPECT for the Preoperative Cardiac Risk Evaluation in Noncardiac Surgery.
Myung Chul LEE ; Dong Soo LEE ; Won Jun KANG ; June Key CHUNG ; Seok Tae LIM
Korean Journal of Nuclear Medicine 1999;33(3):273-281
PURPOSE: We investigated whether myocardial SPECT had additional usefulness to clinical, functional or surgical indices for the preoperative evaluation of cardiac risks in noncardiac surgery. MATERIALS AND METHODS: 118 patients (M: F=66:52, 62.7+/-10.5 years) were studied retrospectively. Eighteen underwent vascular surgeries and 100 nonvascular surgeries. Rest T1-201/stress Tc-99m-MIBI SPECT was performed before operation and cardiac events (hard event: cardiac death and myocardial infarction; soft event: ischemic ECG change, congestive heart failure and unstable angina) were surveyed through perioperative periods (14.6+/-5.6 days). Clinical risk indices, functional capacity, surgery procedures and SPECT findings were tested for their predictive values of perioperative cardiac events. RESULTS: Peri-operative cardiac events occurred in 25 patients (3 hard events and 22 soft events). Clinical risk indices, surgical procedure risks and SPECT findings but functional capacity were predictive of cardiac events. Reversible perfusion decrease was a better predictor than persistent decrease. Multivariate analysis sorted` out surgical procedure risk (p=0.0018) and SPECT findings (p=0.0001) as significant risk factors. SPECT could re-stratify perioperative cardiac risks in patients ranked with surgical procedures. CONCLUSION:: We conclude that myocardial SPECT provides additional predictive value to surgical type risks as well as clinical indexes or functional capacity for the prediction of preoperative cardiac events in noncardiac surgery.
Death
;
Electrocardiography
;
Heart Failure
;
Humans
;
Multivariate Analysis
;
Myocardial Infarction
;
Myocardial Ischemia
;
Perfusion
;
Perioperative Period
;
Retrospective Studies
;
Risk Factors
;
Tomography, Emission-Computed, Single-Photon*
10.Electron microscopic ultrastructural changes of leiomyoma after treatment with D-Trp6-luteinizing hormone releasing hormone.
Ki Hyun PARK ; Myung Chul SHIN ; Bo Yeon LEE ; Byung Seok LEE ; Chan Ho SONG
Korean Journal of Fertility and Sterility 1991;18(2):189-196
No abstract available.
Leiomyoma*