PURPOSE: To evaluate the efficacy of the arterial phase of dynamic spiral CT in the detection of pancreatic adenocarcinoma compared with the late phase. MATERIALS AND METHODS: Two phase spiral CT images of seventeen patients with pathologically proven pancreatic ductal adenocarcinomas were compared retrospectively. CT scans were performed with 5mm collimation at 1:1 pitch table speed. Images of arterial and late phases were obtained at 35 seconds and 180 seconds after initiation of administration of 100mL of contrast material(3mL/sec), respectively. Images of the arterial phase were compared with those of the late phase. RESULTS: Images of the arterial phase showed sufficient contrast between the tumor and adjacent pancreatic parenchyma in 12 cases, insufficient in four cases, and no significant contrast in one case. Images of the late phase showed sufficient contrast in five cases, insufficient in five cases, and no significant contrast in seven cases. Images of the arterial phase was superior to that of the late phase in 12 patients(70.6%). In six of the 12 patients, only the images of the arterial phase showed contrast between the tumor and the adjacent parenchyma. The images of late phase showed only one case of three metastasis detected on the images of the arterial phase. CONCLUSION: The arterial phase of spiral CT is superior to the late phase that is comparable with conventional CT in the detection of pancreatic adenocarcinoma.
Adenocarcinoma* ; Humans ; Neoplasm Metastasis ; Pancreatic Ducts ; Retrospective Studies ; Tomography, Spiral Computed* ; Tomography, X-Ray Computed

No abstract available.
Blood Flow Velocity* ; Humans ; Infant, Newborn*

No abstract available.
Adult* ; Humans

Agressive osteoblastoma is a very rare primary bone tumor having locally aggressive and destructive natures.But distant metastasis is not well occurred. Aggressive osteoblastoma may be similar to osteoblastomaradiologically, but has different pathological featurs. We experienced one case of aggressive osteoblastomaarising from left ilium and report this case with review of the literatures.
Ilium ; Neoplasm Metastasis ; Osteoblastoma

In the studies on the hatching mechanisms in mammals, many investigators focused on the embryonic intrinsic factor(s) in in vitro culture, but the uterine environment as the extrinsic factor(s) is thought to play an important role in hatching mechanism. Therefore, to evaluate the effect of uterine environment on the hatching event in vivo, the immature(GV) and ovulated(MII) oocytes, and the late 2-cell embryos of mouse were transferred to pseudopregnant foster mother's uterus during peri-implantation period. So it was verified whether there would happen hatching by only uterine environment independently on embryonic stage. The ultrastructural changes of the zona surface of transferred group were compared with those of in vivo and vitro group by SEM. 36 hrs after transfer, the immature and ovulated oocytes almost degenerated, and the late 2-cell embryos developed to various embryonic stages. However, the embryos which didn't develop to blastula stage did not hatch. The ultrastructural network of ZP in transferred group seemed to be smoothed uniformly, which was different from in vitro group. In conclusion, it is suggested that the uterine environment during peri-implantation period enhances the embryo hatching by provoking the structural change of ZP.
Animals ; Blastula ; Embryonic Structures* ; Herpes Zoster* ; Humans ; Mammals ; Mice* ; Oocytes* ; Research Personnel ; Uterus ; Zona Pellucida*

PURPOSE: To compare the images of arterial phase (AP) and portal venous phase (PVP) in the evaluation of conspicuousness of lesion and peripancreatic arterial and venous opacification in pancreatic diseases. MATERIALS AND METHODS: Dual-phase spiral CT was performed in 37 patients with pancreatic adenocarcinoma and 21 patients with pancreatitis. CT scans were performed with 5mm collimation at 1 : 1 pitch table feed. Images of AP and PVP were obtained at 30 and 65 seconds after administration of contrast material, was initiated. Using a gradingsystem, images were analalysed for conspicuousness of lesion and vascular opacification(grade 1=good, grade2=fair, grade 3=poor). RESULTS: In pancreatic adenocarcinoma, 35 and 36 of 37 cases showed low attenuation on APand PVP, respectively. With regard to conspicuousness of tumour, PVP(mean grade : 1.24) was superior AP(mean grade: 1.43), but not significantly(p=0.0745). In arterial opacification, AP(mean grade : 1.03) was significantly superior to PVP(mean grade : 1.30, ; p=0.0051). In venous opacification, PVP(mean grade : 1.19) was significautlyto AP(mean grade : 2.41 ; p<0.0001). In pancreatitis, 14 and 15 of 21 cases showed localized hypo-attenuating lesion indicating necrosis or fluid collection, on AP and PVP, respectively. With regard to conspicuousness oflesion, PVP(mean grade : 1.61) was superior to AP(mean grade : 1.81), but not significantly(p=0.1088). In arterial opacification, AP(mean grade : 1.05) was significantly superior to PVP(mean grade: 1.38 ; p=0.0180). In venous opacification, PVP(mean grade : 1.10) was significantly superior to AP(mean grade : 2.33 ; p=0.0005). CONCLUSION: For the diagnosis and staging of pancreatic disease, dual-phase spiral CT in arterial and portal venous phase maybe recommendable. The portal venous phase of spiral CT seems, however, to be superior to the arterial phase because the lesion is more conspicuous and there is venous opacification.
Adenocarcinoma ; Diagnosis ; Humans ; Necrosis ; Pancreas* ; Pancreatic Diseases ; Pancreatitis ; Tomography, Spiral Computed* ; Tomography, X-Ray Computed

No abstract available.
Femur* ; Hip*

Diffuse tremendous thickening of gastric wall caused by excessive proliferation of the mucosa of unknown causewas first decribed by Menetrier in 1888. The disease is highly uncommon, but the exact preoperative diagnosis iscrucial because of the more excellent prognosis than other malignant lesions including gastric lymphoma andinfiltrative gastric carcinoma. The authors recently experienced a case of Menetrier's disease which had beendiagnosed as gastric lymphoma preoperatively. Radiologic differentiation is not impossible between this extermelyrare disease and other mimicking malignant lesions, that is the reason why we introduce radiographic findings ofthe case by comparison with gastric lymphoma of giant rugal type and infiltrative gastric carcinoma. Typical upperG-I series findings of the case are: 1) Enlarged tortuous proximal gastric rugal folds only along the greatercurvature, 2) Perpendicular lines of barium spicules trapped by apposed folds with clubbed or forked appearance,3) Abrupt transition of transion to normal stomach, 4) No luminal narrowing and retained but sluggish peristalsis.Thus radiologists can diagnose Menetrier's disease scrupulously based on critical application of enlarged foldspattern and extent of the lesion in association with other radiologic features and clinial history of fairly longduration. Brief review of clinical and pathologic features about Menetrier's disease is included.
Barium ; Diagnosis ; Diagnosis, Differential ; Gastritis, Hypertrophic ; Hypertrophy ; Lymphoma ; Mucous Membrane ; Phenobarbital ; Prognosis ; Stomach

PURPOSE: To assess the usefulness of MRI in the detection of a single ectopic ureteral opening and thelocation and dysplastic change of ipsilateral kidney. MATERIALS AND METHODS: Nine patients (mean age; 4.8 years,M:F=3:6) in whom a single ectopic ureter was suspected clinically and sonographically underwent conventionalradiologic studies ( IVP, VCUG, 99mTc-DM-SA scan, as well as US) and MRI. We evaluated images of the point of theectopic ureteral opening and the location and dysplastic or hydronephrotic change of the ipsilateral kidney, andcompared those findings with the endoscopic, surgical, and pathological findings. RESULTS: Eight patients had aunilateral single ectopic ureter and one had bilateral lesions. Seven normally positioned kidneys in six patientsshowed dysplastic (n=3) or hydronephrotic (n=4) change. In two patients an ectopic dysplastic kidney was locatedin the pelvis and one had ipsilateral renal agenesis. Conventional radiologic studies failed to reveal twoectopic dysplastic kidneys, one renal agenesis, and eight ectopic ureteral openings. In all patients, MRI clearlydemonstrated the location of the kidney and ectopic ureteral opening, and dysplastic or hydronephrotic change ofthe kidney, and in one patient, uterine duplication. Except in two patients whose ectopic ureteral opening was notfound on endoscopy, MRI findings were concordant with endoscopic and surgical findings. CONCLUSION: MRI wasuseful for the detection of a single ectopic ureteral opening and for demonstrating the location and dysplasticchange of ipsilateral kidney.
Child* ; Endoscopy ; Humans ; Kidney* ; Magnetic Resonance Imaging* ; Pelvis ; Ureter*

A case of nonfunctioning pancreatic islet cell tumor is described. A 34 years old female patient had intermittent epigastric pain and nausea for 6 months and she had nothing suggestive of neuroendocrine symtoms. Physcial examination showed an epigastric mass which wae deepseated, nontender, and well-demarcated. The routine upper endoscopic evatuation was negative. Abdominal ultrasonography and computed tomography showed a well-defined round solid mass with multifocal necrosis but did not revealed the origin of the lesion. Endoscopic retrograde pancreatography showed upward and rightward displacement of the proximal body portion of main pancreatic duct with nonvisualization of the secondary branches of pancreatic duct, suggesting that the mass originated from the pancreas. Resection of the mass with partial pancreatectomy and Roux-en-Y pancreaticojejunostomy was perfomed and the pathology was coafirmed as nonfunctioning pancreatic islet cell tumor containing somatostatin by immunohistochemical technique.
Adenoma, Islet Cell ; Adult ; Female ; Humans ; Immunohistochemistry ; Islets of Langerhans* ; Nausea ; Necrosis ; Pancreas ; Pancreatectomy ; Pancreatic Ducts ; Pancreaticojejunostomy ; Pathology ; Somatostatin ; Ultrasonography