1.Diagnostic Value of Tendon Reflex in Diabetic Peripheral Neuropathy.
Myung Joon JEE ; Kil Ho CHO ; Seo Ra YOON ; Kwang Jin SEON
Journal of the Korean Academy of Rehabilitation Medicine 1999;23(2):303-309
OBJECTIVE: To investigate the role of tendon reflex test in the diagnosis of diabetic peripheral neuropathy. METHOD: Patellar tendon reflex (PTR) and achilles tendon reflex (ATR) were recorded in forty six diabetic patients and thirty seven normal adults by delivering tendon taps with an electric reflex hammer. Forty six diabetic patients were divided into two groups based on nerve conduction study and diabetic neuropathy score: group 1 consisted of nineteen patients with peripheral neuropathy, group 2 consisted of twenty seven patients without peripheral neuropathy. Multiple regression equations using latency as a variable dependent on age and height were used and upper crossing of the 3 standard deviation level with regression on height and age was considered abnormal. RESULTS: Mean latencies of PTR and ATR were prolonged in the diabetic patients in comparison with the controls (p<0.01) and were prolonged in group 1 compared to group 2. In group 1, PTR was abnormal in 14 cases (sensitivity: 73.6%, specifity: 88%) and ATR was abnormal in 13 cases (sensitivity: 68.4%, specifity: 85.1%). In group 2, PTR was abnormal in 3 cases and ATR was abnormal in 4 cases. CONCLUSION: Tendon reflex test would be a valuable supplement to conventional nerve conduction studies for detection of diabetic peripheral neuropathy, especially in the proximal segment.
Achilles Tendon
;
Adult
;
Diabetic Neuropathies
;
Diagnosis
;
Humans
;
Neural Conduction
;
Patellar Ligament
;
Peripheral Nervous System Diseases*
;
Reflex
;
Reflex, Stretch*
;
Tendons*
2.Comparison of Postoperative Stability between Distraction Osteogenesis and Bilateral Sagittal Split Ramus Osteotomy in Mandibular Retrognathism
Myung Su YOU ; Jee Ho LEE ; Myung Jin KIM
Journal of the Korean Association of Maxillofacial Plastic and Reconstructive Surgeons 2012;34(2):100-105
0.05). Mean follow up periods were 10.77 months for BSSRO group and 11.28 months for DO group, respectively. After mandibular advancement, mean positional changes in the condyle were 0.56+/-1.43 mm horizontally and 0.72+/-1.61 mm vertically for BSSRO group and 0.53+/-1.56 mm horizontally and 0.56+/-1.75 mm vertically for DO group, respectively. Mean change of distance from B point to Y-axis was -1.76+/-0.83 mm for BSSRO group and -2.14+/-1.82 mm for DO group, respectively. According to the condylar position and B point, there were no significant differences in postoperative stability between the two groups (P>0.05).CONCLUSION: There was no significant difference in postoperative stability between DO and BSSRO group according to condylar position and B point. Based on the results of the present study, it is hypothesized that DO would be a good treatment choice for severe mandibular retrognathism because DO could achieve more mandibular advancement and concurrent soft tissue elongation.]]>
Follow-Up Studies
;
Humans
;
Mandible
;
Mandibular Advancement
;
Mandibular Osteotomy
;
Osteogenesis, Distraction
;
Osteotomy, Sagittal Split Ramus
;
Retrognathia
3.The relationship of p63 expression with cell proliferation and apoptosis in DMBA-induced hamster buccal pouch carcinogenesis.
Jee Hyun PARK ; Won Deok LEE ; Chul Gi MIN ; Jin Han KANG ; Hoon MYUNG ; Jong Ho LEE ; Myung Jin KIM
Journal of the Korean Association of Oral and Maxillofacial Surgeons 2005;31(3):219-227
PURPOSE: Abnormalities in the p53 gene are regarded as the most consistent genetic abnormalities detected in head and neck squamous cell carcinogenesis. Two new members of the p53 gene family, p73 and p63 have recently been identified. They share considerable sequence homology with p53 in the transactivation, DNA binding, and oligomerization domains, indicating possible involvement in carcinogenesis. Disruption of the homeostatic balance between proliferation and apoptosis is widely believed to contribute to human oral carcinogenesis. The aim of this study was to analyze expression of p63 in squamous cell carcinogenesis and to compare with immunochemical markers representing cell proliferation and apoptosis. MATERIALS AND METHODS: Using the Syrian hamster oral cancer model, the fraction of apoptotic (apoptotic index-AI), proliferating (mitotic index-MI) and p63 expressing keratinocytes were examined at normal, dysplastic and malignant oral epithelium using the TUNEL assay, PCNA and p63 immunostaining. RESULTS: p63 significantly increased between normal and dysplastic epithelium and between dysplastic and malignant epithelium. PCNA significantly increased between normal and dysplastic epithelium and between normal and malignant epithelium. However, increase between dysplastic and malignant epithelium, though still increasing, was not statistically significant. The percentage of TUNEL positive cells increased from normal to dysplastic epithelium and returned to normal keratinocyte level in the malignant epithelium. However, differences between tissue types were not significant. The ratio of MI:AI increased significantly only in the dysplastic-malignant epithelial transition. The increase of p63 expression closely reflected the change in the MI:AI ratio during oral carcinogenesis. CONCLUSION: The p63 may be associated with the regulation of epithelial proliferation and apoptosis in DMBA-induced hamster buccal pouch squamous cell carcinogenesis. Further study is required to investigate which p63 isoforms are involved in hamster buccal pouch carcinogenesis.
9,10-Dimethyl-1,2-benzanthracene
;
Animals
;
Apoptosis*
;
Carcinogenesis*
;
Cell Proliferation*
;
Cricetinae*
;
DNA
;
Epithelium
;
Genes, p53
;
Head
;
Humans
;
In Situ Nick-End Labeling
;
Keratinocytes
;
Mouth Neoplasms
;
Neck
;
Proliferating Cell Nuclear Antigen
;
Protein Isoforms
;
Sequence Homology
;
Transcriptional Activation
4.NutriSonic web expert system for meal management and nutrition counseling with nutrient time-series analysis, e-food exchange and easy data transition.
Soon Myung HONG ; Jee Ye CHO ; Jin Hee LEE ; Gon KIM ; Min Chan KIM
Nutrition Research and Practice 2008;2(2):121-129
This study was conducted to develop the NutriSonic Web Expert System for Meal Management and Nutrition Counseling with Analysis of User's Nutritive Changes of selected days and food exchange information with easy data transition. This program manipulates a food, menu and meal and search database that has been developed. Also, the system provides a function to check the user's nutritive change of selected days. Users can select a recommended general and therapeutic menu using this system. NutriSonic can analyze nutrients and e-food exchange ("e" means the food exchange data base calculated by a computer program) in menus and meals. The expert can insert and store a meal database and generate the synthetic information of age, sex and therapeutic purpose of disease. With investigation and analysis of the user's needs, the meal planning program on the internet has been continuously developed. Users are able to follow up their nutritive changes with nutrient information and ratio of 3 major energy nutrients. Also, users can download another data format like Excel files (.xls) for analysis and verify their nutrient time-series analysis. The results of analysis are presented quickly and accurately. Therefore it can be used by not only usual people, but also by dietitians and nutritionists who take charge of making a menu and experts in the field of food and nutrition. It is expected that the NutriSonic Web Expert System can be useful for nutrition education, nutrition counseling and expert meal management.
Counseling
;
Expert Systems
;
Fees and Charges
;
Follow-Up Studies
;
Internet
;
Meals
5.Comparison of Meal Satisfaction, Dietary Habits, and Nutrient Intakes according to School Lunch Support among Middle School Boys and Girls in Incheon.
Jee Young PARK ; Eun Jin KIM ; Myung Hee KIM ; Mi Kyeong CHOI
Journal of the Korean Dietetic Association 2012;18(1):1-15
The purpose of this study was to provide fundamental data for health promotion and improvement of the dietary life in students who receive school lunch support (SLS) by comparative analysis of food service satisfaction, dietary habits, and nutrition intakes according to SLS. The subjects of this study consisted of 258 boys and 233 girls at a middle school in Incheon. The students' average age was 14.9 years, average height was 161.3 cm, and average weight was 52.0 kg. The breakfast eating frequency of the No-SLS (NSLS) group was significantly greater than that of the SLS group (P<0.05). The time spent for eating breakfast in the SLS group was significantly shorter than that of the NSLS group for boys. There was no significant difference in dietary attitudes according to SLS. For satisfaction of the quantity and diversity of the school lunch menu in girls, the SLS group had higher satisfaction than the NSLS group. The daily energy intake of the SLS group was significantly lower than that of the NSLS group in both boys and girls. The majority of daily nutrients intakes in the SLS group were also significantly lower than those in the NSLS group. In summary, the female students in the SLS group were more satisfied with school lunch service than general students. However, SLS students less frequently ate breakfast and showed lower energy and nutrient intakes. Therefore, in order to improve the nutritional status and dietary life of students who receive school lunch support, consistent nutrition management and support in schools are required.
Adolescent
;
Breakfast
;
Eating
;
Energy Intake
;
Female
;
Food Habits
;
Food Services
;
Health Promotion
;
Humans
;
Lunch
;
Meals
;
Nutritional Status
6.Synchronous Occurrence of a Gastric Adenocarcinoma and a GIST (Gastrointestinal Stromal Tumor): A Case Report.
Sung Bae JEE ; Kyung Jin SEO ; Hun HEO ; Hae Myung JEON
Journal of the Korean Gastric Cancer Association 2007;7(4):261-265
A gastric adenocarcinoma is the second most common cause of cancer deaths worldwide, but there are some geographical differences in its incidence. A gastrointestinal tumor is an uncommon disease with a wide spectrum of aggressive behavior. These two tumors have a distinct pathogenesis, and synchronous occurrence of an adenocarcinoma and a GIST (gastrointestinal stromal tumor) in the stomach is very rare. We report a case of synchronous occurrence of a gastric adenocarcinoma and GIST in a 64-year-old man. We performed the following tests: barium swallowing test, gastroduodenoscopy, and CT scanning. We performed a total gastrectomy, and a 9 cm-sized GIST at the fundus and a small early gastric cancer at the antrum were confirmed pathologically. Some explanations for this rare case exist, but in our opinion, the synchronous occurrence is a rare but probable event that can happen in an endemic area. We describe a case of synchronous occurrence of a gastric adenocarcinoma and GIST in the stomach, with a review of the literature.
Adenocarcinoma*
;
Barium
;
Deglutition
;
Gastrectomy
;
Gastrointestinal Stromal Tumors
;
Humans
;
Incidence
;
Middle Aged
;
Stomach
;
Stomach Neoplasms
;
Tomography, X-Ray Computed
7.Usefulness of Coronal MR Image in Diagnosis of Foraminal and Extraforaminal Disc Herniation.
Myung Ho KIM ; Kyung Jin SUH ; Jee Young LEE ; Sang Hyuk MIN ; Hyun Yul YOO
Journal of Korean Society of Spine Surgery 2008;15(3):165-173
STUDY DESIGN: This is a retrospective study OBJECTIVES: The coronal MR images were carefully evaluated to document the efficacy of diagnosing foraminal and extraforaminal disc herniations. SUMMARY OF LITERATURE REVIEW: Extraforaminal disc herniations constitute 1~11.7% of all disc herniations. The diagnosis of it demands great caution because it must be distinguished from intraspinal canal disc herniation. Diagnosing extraforaminal disc herniations can be neglected with using ordinary diagnostic methods. MATERIALS AND METHODS: A retrospective analysis was performed on 24 patients, (26 cases) that underwent lumbar spine MRI, with the T2 coronal images, for the evaluation of disc herniations from March 2006 to March 2007. Every MRI image of each patient who had foraminal or extraforaminal disc herniations was graded according to the Pfirrmann's classification of diagnostic efficacy by two spinal surgery specialists and two radiology specialists. RESULTS: There were 13 cases of foraminal disc herniation and 13 cases of extraforaminal disc herniation in all 26 cases that were diagnosed by MRI. The coronal and axial images were more effective than the sagittal images for the discrimination of a compressed root. Especially, for the extraforaminal disc herniation, all of the coronal images were graded as grade 3; on the other hand, all of the sagittal images were not helpful for the assessment and the axial images were graded as grade 2 for 38.5% of the and as grade 3 for 61.5%. So, the coronal images were most effective for making the diagnosis of extraforaminal disc herniation and this was statistically significant (p<0.05). CONCLUSION: For the accurate discrimination of the location and the grading of foraminal and extraforaminal disc herniation, MRI, and especially the coronal images, is an effective and useful method in addition to conducting a physical examination.
Discrimination (Psychology)
;
Hand
;
Humans
;
Retrospective Studies
;
Specialization
;
Spine
8.Perinatal Outcome in Twin Pregnancies after in Vitro Fertilization and Embryo Transfer : Comparison between Reduced and Non-reduced Twins.
Myung Hee KIM ; Seok Hyun KIM ; Byung Chul JEE ; Chang Suk SUH ; Young Min CHOI ; Chang Jae SHIN ; Jung Gu KIM ; Shin Yong MOON ; Jin Yong LEE
Korean Journal of Obstetrics and Gynecology 1997;40(8):1586-1593
Multifetal pregnancy reduction(MFPR) has been suggested to improve pregnancy outc-ome in multifetal pregnancies with three or more fetuses after assisted reproductive techn-ology(ART) such as IVF-ET program, and now it seems to be a rather safe and effective mothod to reduce perinatal loss associated with multifetal pregnancies. To investigate the effectiveness of MFPR, the perinatal outcome of twin pregnancies in IVF-ET patients was analyzed in 3 groups : Group I-12 infertile patients who had conceived more than quadru-plet pregnancy and underwent MFPR to twin pregnancy, Group II-29 patients who had conceived triplet pregnancy and underwent MFPR to twin pregnancy, and Group III-30 pat-ients who had conceived twin pregancy initially and served as control group. Among 3 gr-oups, fetal loss rate before 24 weeks of gestation, pregnancy non-reduced, complications, gestational age at delivery, and birth weight were compared. Fetal loss rate after MFPR was significantly higher in Groups I(41.7%) and Group II(17.2%) compared with Group III(3.3%), and positively correlated with the number of fetuses before MFPR in Groups I and II. However, pregnancy complication rate was not significantly different among 3 groups(41.7%, 48.3%, and 36.7%). After exclusion of fetal loss cases before 24 weeks, mean gestational age at twin delivery and mean birth weight were not significantly different among 3 groups(36.2 weeks, 36.6 weeks, and 36.1 weeks ; 2.37 kg, 2.45 kg and 2.47kg).In conclusion, MFPR in multifetal pregnancies is an ethically justified procedure that may improve perinatal outcome in cases of multifetal pregnancies.
Birth Weight
;
Embryo Transfer*
;
Embryonic Structures*
;
Fertilization in Vitro*
;
Fetus
;
Gestational Age
;
Humans
;
Pregnancy
;
Pregnancy Complications
;
Pregnancy, Triplet
;
Pregnancy, Twin*
9.Implant surgery based on computer simulation surgical stent and the assessment with the image fusion technique.
Jee Ho LEE ; Soung Min KIM ; Jun Young PAENG ; Myung Jin KIM
Journal of the Korean Association of Oral and Maxillofacial Surgeons 2010;36(5):402-407
INTRODUCTION: The planning of implant surgery is an important factor for the implant prosthesis. Stereolithographic (SLA) surgical stents based on a computer simulation are quite helpful for clinicians to perform the surgery as planned. Although many clinical and technical trials have been performed for computed tomography (CT)-guided implant stents to improve the surgical procedures and prosthetic treatment, there are still many problems to solve. We developed a system of a surgical guide based on 3 dimensional (3D) CT for implant therapy and achieved satisfactory results in the terms of planning and operation. MATERIALS AND METHODS: Fifteen patients were selected and 30 implant fixtures were installed. The preoperative CT data for surgical planning were prepared after obtaining informed consent. Surgical planning was performed using the simulation program, Ondemend3D In2Guide. The stents were fabricated based on the simulation data containing information of the residual bone, the location of the nerve, and the expected design of the prostheses. After surgery with these customized stents, the accuracy and reproducibility of implant surgery were evaluated based on the computer simulation. The data of postoperative CT were used to confirm this system using the image fusion technique and compare the implant fixtures between the planned and implanted. RESULTS: The mean error was 1.18 (+/-0.73) mm at the occlusal center, 1.23 (+/-0.67) mm at the apical center, and the axis error between the two fixtures was 3.25degrees (+/-3.00). These stents showed superior accuracy in maxilla cases. The lateral side error at the apical center was significantly different from the error at the occlusal center but there were no significant differences between the premolars, 1st molars and 2nd molars. CONCLUSION: SLA surgical stents based on a computer simulation have the satisfactory accuracy and are expected to be useful for accurate planning and surgery if some errors can be improved.
Axis, Cervical Vertebra
;
Bicuspid
;
Computer Simulation
;
Humans
;
Informed Consent
;
Maxilla
;
Molar
;
Prostheses and Implants
;
Stents
10.Bacterial Species Analysis and Proper Antibiotic Choices of Preauricular Fistular Abscess.
Min Han KWON ; Jin Oh YI ; Kyung Hoon CHEON ; Myung Soo KWAK ; Jee Ho YANG ; Sang Kyu PARK
Korean Journal of Otolaryngology - Head and Neck Surgery 2012;55(10):623-627
BACKGROUND AND OBJECTIVES: Infection of congenital preauricular fistula leads to preauricular abscess. Generally, the treatment for preauricular abscess is focused on subsiding abscess. Although incision & drainage is major point of therapy, the study of bacterial species and antibiotics for preauricular abscess is scant in literature. So, we investigated the most common species that cause preauricular abscess and the choice of proper antibiotics by using the databse available from the last 10 years. SUBJECTS AND METHOD: Our studies, from January, 2000 to December, 2010, included 86 patients in total (all in patients & out patients). We performed a retrospective review of bacterial species and culture analysis of each preauricular abscess. RESULTS: In this study, it was shown that most common pathogens causing preauricular fistula infection were Staphylococcus (27.9%), Enterococcus (9.3%), streptococcus and Klebsiella (5.8%) and Peptostreptococcus (4.6%). And Amoxicillin/cavulanate, Ciprofloxacin, Clindamycin had excellent effects of minimal inhibitory concentration through multiple pathogens. CONCLUSION: The choice of antibiotics for preauricular abscess will be targeted on Staphylococcus, Enterococcus, Streptococcus and anaerobic infection. Amoxicillin/clavulanate or Ciprofloxacin are the most effective antibiotics.
Abscess
;
Anti-Bacterial Agents
;
Ciprofloxacin
;
Clindamycin
;
Drainage
;
Enterococcus
;
Fistula
;
Humans
;
Klebsiella
;
Peptostreptococcus
;
Retrospective Studies
;
Staphylococcus
;
Streptococcus