Measurement of various portions of the corpus callosum was performed on magnetic resonance(MR) images of 114 subjects with no known or suspected corpus callosal disorders. Midsagittal T1-weighted images used for measurements and mean diameters of various portions in each age and sex group were obtained. Measures of five portions were made : (A) the anterio-posterior length, (B) the diameter of genu portion, (C) the diameter of splenium, (D) the diameter of and mid-body portion, (E) the diameter of narrow portion at the body of corpus callosum. The mean diameter in each gender group for A, B, C, D, and E were 68.8mm, 12.1mm, 12.3mm, 6.9mm, 4.1mm in male and 69.9mm, 12.0mm, 12.1mm, 6.4mm, 4.1mm in female, respectively. The groups of 0-9 years of both genders showed the minimum mean value in each portion.
Corpus Callosum* ; Female ; Humans ; Male ; Sex Differentiation*

Reactive perforating collagenosis, first described by Mehregan et al in ]967, is a skin disorder characterized by transepidermal eliniination of altered collagen fibers. This rare disease appears as recurrent, umbilicated, crusted papules in response to minor trauma. We report here a case of reactive perforating collagenosis in a 21-year-old man. Examination of the skin revealed a number of centrally umbilicated, asymptomatic papules filled with keratotic plugs in various development and regression. The lesions were distributed on the dorsa of the hands, face, and neck. The biopsy spccimen showed a few of thin bundles of collagen which v ere extruded from the dermis through the atrophic epidermis and the turinels within the epidermis, reaching the buttom of the plug.
Biopsy ; Collagen ; Dermis ; Epidermis ; Hand ; Humans ; Neck ; Rare Diseases ; Skin ; Young Adult

To establish the hematological reference values in the healthy adults visited our hospitals, following examination were done on 2823 persons by Coulter Counter Model S-plus II ; white blood cell count (WBC), red blood cell count (RBC), hemoglobin (Hb), hematocrit (Hct), meant corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), mean corpuscular hemoglobin concentration (MCHC), red cell distribution width (RDW), platelet, plateletcrit, mean platelet volume (MPV) and platelet distribution width (PDW). The following results are obtained. 1) Male, mean value of WBC; 6,800±2,680 (2SD)/µl Female, mean value of WBC; 5,950±2,380 (2SD)/µl 2) Male, mean value of RBC; 428±60 (2SD)x104/µl Female, mean value of RBC; 415±56 (2SD)x104/µl 3) Male, mean value of Hb; 15.4±1.8 (2SD) g/dL Female, mean value of Hb; 13.0±1.6 (2SD) g/dL 4) Male, mean value of Hct; 45.3±5.0 (2SD)% Female, mean value of Hct; 38.2±4.6 (2SD)% 5) Male, mean value of MCV; 93.8±5.8 (2SD) fL Female, mean value of MCV; 92.2±7.4 (2SD) fL 6) Male, mean value of MCH; 31.8±2.2 (2SD) pg Female, mean value of MCH; 31.4±2.8 (2SD) pg 7) Male, mean value of MCHC; 34.0±1.2 (2SD)% Female, mean value of MCHC; 33.9±1.2 (2SD)% 8) Male, mean value of RDW; 12.7±1.0 (2SD)% Female, mean value of RDW; 12.6±1.4 (2SD)% 9) Male, mean value of Platelet; 242.9±87.8 (2SD) X103/µl Female, mean value of Platelet; 242.2±89.0 (2SD) X103/µl 10) Male, mean value of Plateletcrit; 0.201±0.076 (2SD)% Female, mean value of Plateletcrit; 0.204±0.076 (2SD)% 11) Male, mean value of MPV; 8.20±1.70 (2SD) fl Female, mean value of MPV; 8.36±1.82 (2SD) fl 12) Male, mean value of PDW; 16.1±0.8 (2SD)% Female, mean value of PDW; 16.0±0.8 (2SD)%
Adult* ; Blood Platelets ; Erythrocyte Count ; Erythrocyte Indices ; Female ; Hematocrit ; Humans ; Leukocyte Count ; Male ; Mean Platelet Volume ; Reference Values*

A case of multiple myeloma combined with stomach cancer and related literatures were reviewed. A 67 year-old male patient entered the hospital with dysphagia and weight loss for 3 months. Peripheral blood examination revealed anemia with rouleaux formation. Total protein of the serum was 9.9 g/dl with hyperglobulinemia (albumin 2.7 g/dl, globulin 7.2 g/dl, A/G ratio 0.375). On the electrophoresis and immunoelectrophoresis of the serum, the abnormal protein with the pattern of monoclonal gammopathy (IgG-K type) was shown. There were multiple variable sized osteolytic lesions on skull X-ray and abnormal hot uptakes of rips on bone scan and result of rib biopsy was plasmacytoma. Gastrofiberscopy was performed to search for the cause of upper gastrointestinal bleeding, revealed stomach cancer, and the result of the gastric mucosal biopsy proved to be well-differentiated adenocarcinoma.
Adenocarcinoma ; Anemia ; Biopsy ; Deglutition Disorders ; Electrophoresis ; Hemorrhage ; Humans ; Immunoelectrophoresis ; Male ; Multiple Myeloma* ; Paraproteinemias ; Plasmacytoma ; Ribs ; Skull ; Stomach Neoplasms* ; Stomach* ; Weight Loss

The giant cell tumor is a primary. neoplasm of bone characterized histollogically by a vascularized network of plumpish or ovoid stromal cells heavily interposed with multinucleated giant cells. The majority of cases occur in patients between 20 and 40 years old and in the long tubular bones, particuarly in proximity to the epiphysis. A rare case of giant cell tumor involving the patella was recently experienced by authors. Case summary with brief review of reference is presented.
Epiphyses ; Giant Cell Tumors ; Giant Cells ; Humans ; Patella ; Stromal Cells

No abstract available.
Collagen Type IV* ; Mucocutaneous Lymph Node Syndrome* ; Ventricular Function, Left*

No abstract available.
Takayasu Arteritis*

A case of Epidermolysis Bullosa Dystrophica is reported with review of pathogenesis with literatures. Epidermolysis Bulloaa Dystrophica is a rare genetic disease which is characterized by the formation of blister upon the minor trauma or friction to the skin. A 7-year old boy was referred to our dept. in Aug. 1976 because of a severe bullous eruption primarily on his hands and feet. On admission tense bullae were noted on the dorsa of hands and feet which is usually serous but may be hermorhagic tendency. Soon thereafter tbis bullous lesion tend to break down into painful shallow denudation which may leave depigmented scars and milia after healing. Family history was negative for skin disorders.
Blister ; Child ; Cicatrix ; Epidermolysis Bullosa Dystrophica* ; Epidermolysis Bullosa* ; Foot ; Friction ; Hand ; Humans ; Male ; Skin ; Transcutaneous Electric Nerve Stimulation

No abstract available.
Twins, Conjoined*

BACKGROUND: Peripheral nerve injury may produce a syndrome consisting of spontaneous pain, allodynia and hyperpathia. Cholinesterase inhibitors are known to have an antinociceptive effect in hot plate and tail flick tests and to be mediated by spinal muscarinic system. The purpose of the current study was to determine the effect of intrathecally (i.t.) administered edrophonium and neostigmine on the touch-evoked allodynia and to identify the antagonism of antiallodynia in a rat model of neuropathic pain. METHODS: Sprague Dawley rats were prepared with tight ligation of left L5/L6 spinal nerves with 6~0 black silk and chronic lumbar intrathecal catheters. After obtaining the baseline hindpaw withdrawal scores, edrophonium (3~100ug) or neostigmine (0.3~10ug) was administered intrathecally. Tactile allodynia was measured using von Frey filaments and allodynic threshold was calculated by updown method. Motor dysfunction was assessed by observing righting/stepping reflex responses and abnormal weight bearing. To examine the reversal of antiallod ynia, muscarinic receptor antagonist atropine (10ug) or nicotinic receptor antagonist mecamylamine (10ug) was injected intrathecally 5 min. prior to injection of edrophonium or neostigmine. RESULTS: I.t. edrophonium and i.t. neostigmine produced a dose dependent antagonism of allodynic state but had moderate to severe effect on motor weakness at doses of 3 and 10 g of neostigmine. Pretreatment with i.t. atropine yielded a complete antagonism of antiallodynia in both drugs, but i.t. mecamylamine did not significantly reverse incresed allodynic threshold. CONCLUSIONS: These experiments suggest that i.t. edrophonium or i.t. neostigmine produces a dose dependent antagonism on touch-evoked allodynia at the spinal level and this antagonism is likely due to spinal muscarinic system.
Atropine ; Catheters ; Cholinesterase Inhibitors ; Edrophonium* ; Hyperalgesia ; Ligation ; Mecamylamine ; Models, Animal ; Neostigmine* ; Neuralgia* ; Peripheral Nerve Injuries ; Rats, Sprague-Dawley ; Receptors, Muscarinic ; Receptors, Nicotinic ; Reflex ; Silk ; Spinal Nerves ; Weight-Bearing