1.A Percutaneous Cross Pinning Method for Supracondylar Fracture of the Humerus : The Significance of Elbow Position during Pinning to Avoid Ulnar Nerve Damage
Jong Deuk RHA ; Myung Ho LEE ; Hyun Soo PARK ; Woo Cheon LEE ; Tong Hoon SA
The Journal of the Korean Orthopaedic Association 1995;30(5):1404-1407
The percutaneous pinning is a simple, effective method for the treatment of displaced supracondylar fractures of the humerus in children. But there is some controversy in the number of pins used and the method of pin insertion. The cross pinning method provides more stability at the fracture site but the risk of ulnar nerve damage is higher than in lateral pinning method, The senenty-one displaced extension type supracondylar fractures were treated by closed reduction and percutaneous cross pinning from January 1991 to October 1994. Among them, the medial pin was inserted in elbow extension in twenty-eight cases and in forty- three cases the medial pin was inserted in elbow flexion. Ulnar nerve injury occured postoperatively in six cases, in which the pin was inserted with the elbow in flexion position. These results may suggest that when percutaneous cross pinning method is selected to fix the supracondylar fracture of the humerus, it would be safer to insert one or two lateral pins with the elbow in full flexion position followed by one medial pin in extension position in order to reduce the risk of loss of reduction and ulnar nerve damage.
Child
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Elbow
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Humans
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Humerus
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Methods
;
Ulnar Nerve
2.Bilateral congenital absence of the patella: A case report.
Jong Deuk RHA ; Yong Hoon KIM ; Sung Il YOON ; Myung Ho LEE ; Duk Ryeon KIM
The Journal of the Korean Orthopaedic Association 1993;28(2):895-899
No abstract available.
Patella*
3.Reconstruction of Medial Malleolus and Deltoid Ligament using Bone
Yong Hoon KIM ; Jong Deuk RHA ; Myung Ho LEE ; Hyun Soo PARK ; Woo Cheon LEE ; Tong Hoon SA
The Journal of the Korean Orthopaedic Association 1995;30(5):1463-1467
We present a case of medial malleolus and deltoid ligament loss with extensive overlying soft tissue defect from crushing injury. The resultant gross medial ankle instability necessitated deltoid ligament reconstruction using a bone-patellar tendon graft.
Ankle
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Child
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Humans
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Ligaments
;
Patella
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Patellar Ligament
;
Tendons
;
Transplants
4.Reconstruction of Hand and Forearm Injury using Reverse Ulnar Artery Forearm Flap: Six Cases Report
Woo Cheon LEE ; Jong Deuk RHA ; Hyun Soo PARK ; Yong Hoon KIM ; Myung Ho LEE ; Suk Min CHOI
The Journal of the Korean Orthopaedic Association 1995;30(4):1058-1063
There are many methods in reconstruction for skin defect in hand and forearm. Among them, reverse ulnar artery forearm flap has several advantages which are versatile, safe and convenient flap. We report 6 cases of our experiences.
Forearm Injuries
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Forearm
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Hand
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Skin
;
Ulnar Artery
6.Pharmacokinetic comparison of two valproic acid formulations: a plain and a controlled release enteric-coated tablets.
Joung Ho RHA ; In Jin JANG ; Kyung Hoon LEE ; Won Seok CHONG ; Sang Goo SHIN ; Namsoo LEE ; Ho Jin MYUNG
Journal of Korean Medical Science 1993;8(4):251-256
We investigated the single- and multiple dose pharmacokinetics of a new controlled-release formulation (Orfil retard enteric coated tablet) of valproic acid in comparison with those of the plain tablet as a reference. Twelve healthy volunteers were given each formulation of 300 mg in the single-dose study. In the steady-state multiple-dose study, twelve epileptic patients received 1200 mg/day of the reference drug (300 mg 9 AM, 300 mg 3 PM, 600 mg 9 PM) and the test formulation (600 mg 9 AM, 600 mg 9 PM) with at least one week interval in cross-over manner. The AUC values of the test controlled release formulation were 91.7% (95% confidence interval: 78.4-100.4%) of the reference drug in the single-dose study and 98.2% (95% confidence interval: 86.2%-109.9%) in the steady-state study. The AUC's of the two formulations were not significantly different by ANOVA test. The Cmax and Tmax values of the test formulation were significantly different from the values of the reference in single-(Tmax: 158.4%, Cmax: 52.5% of the reference) and multiple-dose study (Tmax: 153.5% of the reference). The MRT values of the test formulation were also significantly greater (129.4% of the reference) in the single-dose study. Regarding the controlled-release characteristics of the test formulation, fluctuation index and percentage fluctuation of the twice a day dosage regimen of the test formulation were comparable with those of the thrice a day dosage regimen of the conventional tablet. Area deviation was even smaller in the test regimen of the controlled release formulation.(ABSTRACT TRUNCATED AT 250 WORDS)
Administration, Oral
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Adult
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Biological Availability
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Delayed-Action Preparations
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Epilepsy/blood/*drug therapy
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Humans
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Male
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Tablets
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Tablets, Enteric-Coated
;
Valproic Acid/*pharmacokinetics
7.Effect of Early Statin Treatment in Patients with Cardiogenic Shock Complicating Acute Myocardial Infarction.
Doo Sun SIM ; Myung Ho JEONG ; Kyung Hoon CHO ; Youngkeun AHN ; Young Jo KIM ; Shung Chull CHAE ; Taek Jong HONG ; In Whan SEONG ; Jei Keon CHAE ; Chong Jin KIM ; Myeong Chan CHO ; Seung Woon RHA ; Jang Ho BAE ; Ki Bae SEUNG ; Seung Jung PARK
Korean Circulation Journal 2013;43(2):100-109
BACKGROUND AND OBJECTIVES: The benefit of early statin treatment following acute myocardial infarction (MI) complicated with cardiogenic shock (CS) has not been well studied. We sought to assess the effect of early statin therapy in patients with CS complicating acute MI. SUBJECTS AND METHODS: We studied 553 statin-naive patients with acute MI and CS (Killip class IV) who underwent revascularization therapy between November 2005 and January 2008 at 51 hospitals in the Korea Acute Myocardial Infarction Registry. Patients were divided into 2 groups: those who received statins during hospitalization (n=280) and those who did not (n=273). The influence of statin treatment on a 12-month clinical outcome was examined using a matched-pairs analysis (n=200 in each group) based on the propensity for receiving statin therapy during hospitalization. RESULTS: Before adjustment, patients receiving statin, compared to those not receiving statin, had a more favorable clinical profile, were less likely to suffer procedural complications, and more likely to receive adequate medical therapy. Patients receiving statin had lower unadjusted in-hospital mortality and composite rate of mortality, MI, and repeat revascularization at 12 months, which remained significantly lower after adjustment for patient risk, procedural characteristics, and treatment propensity. CONCLUSION: In CS patients with acute MI undergoing revascularization therapy, early statin treatment initiated during hospitalization was associated with lower rates of in-hospital death and 12-month adverse cardiac events.
Angioplasty
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Hospital Mortality
;
Hospitalization
;
Humans
;
Hydroxymethylglutaryl-CoA Reductase Inhibitors
;
Korea
;
Myocardial Infarction
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Secondary Prevention
;
Shock
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Shock, Cardiogenic
8.Effect of Early Statin Treatment in Patients with Cardiogenic Shock Complicating Acute Myocardial Infarction.
Doo Sun SIM ; Myung Ho JEONG ; Kyung Hoon CHO ; Youngkeun AHN ; Young Jo KIM ; Shung Chull CHAE ; Taek Jong HONG ; In Whan SEONG ; Jei Keon CHAE ; Chong Jin KIM ; Myeong Chan CHO ; Seung Woon RHA ; Jang Ho BAE ; Ki Bae SEUNG ; Seung Jung PARK
Korean Circulation Journal 2013;43(2):100-109
BACKGROUND AND OBJECTIVES: The benefit of early statin treatment following acute myocardial infarction (MI) complicated with cardiogenic shock (CS) has not been well studied. We sought to assess the effect of early statin therapy in patients with CS complicating acute MI. SUBJECTS AND METHODS: We studied 553 statin-naive patients with acute MI and CS (Killip class IV) who underwent revascularization therapy between November 2005 and January 2008 at 51 hospitals in the Korea Acute Myocardial Infarction Registry. Patients were divided into 2 groups: those who received statins during hospitalization (n=280) and those who did not (n=273). The influence of statin treatment on a 12-month clinical outcome was examined using a matched-pairs analysis (n=200 in each group) based on the propensity for receiving statin therapy during hospitalization. RESULTS: Before adjustment, patients receiving statin, compared to those not receiving statin, had a more favorable clinical profile, were less likely to suffer procedural complications, and more likely to receive adequate medical therapy. Patients receiving statin had lower unadjusted in-hospital mortality and composite rate of mortality, MI, and repeat revascularization at 12 months, which remained significantly lower after adjustment for patient risk, procedural characteristics, and treatment propensity. CONCLUSION: In CS patients with acute MI undergoing revascularization therapy, early statin treatment initiated during hospitalization was associated with lower rates of in-hospital death and 12-month adverse cardiac events.
Angioplasty
;
Hospital Mortality
;
Hospitalization
;
Humans
;
Hydroxymethylglutaryl-CoA Reductase Inhibitors
;
Korea
;
Myocardial Infarction
;
Secondary Prevention
;
Shock
;
Shock, Cardiogenic
9.Coronary Artery Bypass Surgery with Radial Artery: Early Results.
Chan Young NA ; Young Tak LEE ; Kook Yang PARK ; Hae Young LEE ; Wook Sung KIM ; Cheul Hyun PARK ; Min Soo HONG ; Jae Cheun SHIM ; Oh Choon KWON ; Woong Han KIM ; Cheul Hyun CHUNG ; Youn Seop JUNG ; Jae Jin HAN ; Myung Hoon RHA ; Young Kwan PARK ; Sung Nok HONG
The Korean Journal of Thoracic and Cardiovascular Surgery 1997;30(3):275-281
The radial artery as a graft for myocardial revascularization was introduced by Carpentier et al. in the early 1970s. Mid-term results were unfortunately discouraging, and the clinical experience with this graft was interrupted. At the end of the 1980s, these authors reproposed the same arterial conduit with more satisfying results, because of improved technique and pharmacological management of the graft. Between October 1994 and July 1995, 36 patients underwent myocardial revascularization with a radial artery graft in Sejong General Hospital. Left internal mammary artery was concomitantly used as a pedicled graft in 34 patients. Fifteen patients(42%) had a complete arterial graft revascularization. A total of 123 distal anastomoses were performed(average 3.4 per patient), including 36 left internal mammary artery grafts(two sequential in 2 patients), and 23 saphenous vein grafts. The remaining 64 distal anastomoses were performed with radial artery grafts (mean 1.8 per patient). The radial arteries were anastomosed to the circumflex(n=38), diagonal( n=18), right coronary(n=6), and left anterior descending coronary artery(n=2). The percentage of radial artery graft anastomoses(64) to the total anastomoses(123) was 52%. The radial artery was used as a single graft in 10 patients, as a sequential graft in 25 patients, and two grafts in 1 patient. Twenty patients underwent associated procedures : coronary endarterectomy(14), coronary artery patch angioplasty(4), mitral valve repair(1), and repair of ventricular septal rupture(1). One patient died of low cardiac output syndrome and the others had no perioperative myocardial infarction. There are no ischemic and functional complications in the arm or hand after removal of the radial artery. Only 1 patient required reexploration of the arm, for the hematoma evacuation, and 2 patients complained transient thumb dysesthesia of the side of the havested arm. This dysesthesia improved within one month. Postoperative angiographic controls were obtained in 11 patients(31%) postoperative 79 to 210 days(mean 126 days). The patency rate were as follows : left internal mammary artery(100%), saphenous vein(100%), and radial artery(95%). We concluded that the radial artery is useful alternative graft, but long term clinical and angiographic studies are required to dertermine whether wider application is warranted.
Arm
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Cardiac Output, Low
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Coronary Artery Bypass*
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Coronary Vessels*
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Hand
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Hematoma
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Hospitals, General
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Humans
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Mammary Arteries
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Mitral Valve
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Myocardial Infarction
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Myocardial Revascularization
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Paresthesia
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Radial Artery
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Saphenous Vein
;
Thumb
;
Transplants
10.Efficacy and safety of pitavastatins in patients with acute myocardial infarction: Livalo in Acute Myocardial Infarction Study (LAMIS) II.
Young Joon HONG ; Myung Ho JEONG ; Jang Ho BAE ; Seok Kyu OH ; Seung Woon RHA ; Seung Ho HUR ; Sung Yun LEE ; Sang Wook KIM ; Kwang Soo CHA ; In Ho CHAE ; Tae Hoon AHN ; Kee Sik KIM
The Korean Journal of Internal Medicine 2017;32(4):656-667
BACKGROUND/AIMS: We evaluated the efficacy and safety and influence on glucose tolerance by different doses of pitavastatins in acute myocardial infarction (AMI) patients. METHODS: Consecutive 1,101 AMI patients who were enrolled in Livalo in Acute Myocardial Infarction Study (LAMIS)-II were randomly assigned to receive either 2 mg of pitavastatin or 4 mg of pitavastatin orally per day. Primary efficacy endpoint was composite of cardiac death, nonfatal myocardial infarction, target-lesion revascularization, and hospitalization for unstable angina, heart failure or arrhythmic events at 12-month. RESULTS: There was no significant difference in primary efficacy endpoint between 2 mg and 4 mg groups (9.07% vs. 9.13%, p = 0.976). The degree of the reduction of low density lipoprotein cholesterol (LDL-C) was significantly greater in 4 mg group compared to 2 mg group from baseline to follow-up (–42.05 ± 32.73 mg/dL vs. –34.23 ± 31.66 mg/dL, p = 0.002). Fasting plasma glucose level was reduced significantly in both groups (–20.16 ± 54.49 mg/dL in 4 mg group and –24.45 ± 63.88 mg/dL in 2 mg group, p < 0.001 and p < 0.001, respectively) and there was no significant change of glycated hemoglobin in two groups from baseline to follow-up (–0.13% ± 1.21% in 4 mg group and –0.04% ± 1.10% in 2 mg group, p = 0.256 and p = 0.671, respectively). CONCLUSIONS: Although LDL-C was reduced more significantly by using 4 mg of pitavastatin compared to 2 mg of pitavastatin, the event rate was comparable without adverse effects on glucose tolerance in both groups in AMI patients who were enrolled in LAMIS-II.
Angina, Unstable
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Atherosclerosis
;
Blood Glucose
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Cholesterol, LDL
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Death
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Fasting
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Follow-Up Studies
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Glucose
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Heart Failure
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Hemoglobin A, Glycosylated
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Hospitalization
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Humans
;
Hydroxymethylglutaryl-CoA Reductase Inhibitors
;
Myocardial Infarction*