No abstract available.
Helicobacter pylori* ; Helicobacter* ; Urease*

For the morphological analysis of DMBA (9,10-diemethyl-1,2-benzanthracene) induced tumor, thirty Sprague-Dawley rats were received 0.1 ml of a 2% paraffin solution of DMBA into the knee joint cavity, which was repeated three times at an interval of 4 weeks. The induced tumor masses were removed at the 12th week after the first injection. Histological and histochemical examinations (H & E, PAS, alcian blue, Van Gieson, prussian blue, reticulin, PTAH stain) and enzyme histochemical examinations (acid phosphatase, alkaline phosphatase, alpha-naphthyl acetate esterase) were performed. The results were as follows: 1) By the 12th week after the first injection of DMBA, the tumor incidence rate was 20 percent. 2) On histological and histochemical examination, most of the induced tumor disclosed the features of the fibrous histiocytoma originating from mesenchymal cells, and the remains sweat gland adenoma and adenocarcinoma originating from epithelial cells. 3) On enzyme histochemical examination, most of the mesenchymal cell-derived tumor cells showed positive reactions for acid phosphatase and alpha-naphthyl acetate esterase, which were similar characteristic features of enzyme stains as shown in the component cells of fibrous histiocytoma.
Rats ; Animals ; Incidence ; Adenocarcinoma ; Adenoma

A 66 year old man with history of dizziness and occasional headache for a month was found to have right subclavian steal syndrome confirmed by angiogram. Right radial pulse is very weak. Blood pressure on left is 130/70mmHg and on right 70/50. Marked Bruits are audible on right side of neck and shoulder area.
Aged ; Blood Pressure ; Dizziness ; Headache ; Humans ; Neck ; Shoulder ; Subclavian Steal Syndrome*

A 66 year old man with history of dizziness and occasional headache for a month was found to have right subclavian steal syndrome confirmed by angiogram. Right radial pulse is very weak. Blood pressure on left is 130/70mmHg and on right 70/50. Marked Bruits are audible on right side of neck and shoulder area.
Aged ; Blood Pressure ; Dizziness ; Headache ; Humans ; Neck ; Shoulder ; Subclavian Steal Syndrome*

We retrospectively analysed plain radiographs and MR imaging of 16 conventional osteosarcoma cases(8 children, 8 adults) which underwent amputations or limb salvage operations. Pathologic correlation was performed with gross and microscopic sections to evaluate 1) whether the open epiphyseal plate can function as a barrier against transphyseal spread of osteosarcoma and 2) the diagnostic value of MR imaging for the detection of the detection of the epiphyseal involvement of osteosarcoma. In children with open epiphyseal plates, conventional radiographs suggested transphyseal tumor growth in one of eight cases(12.5% and MR imaging in seven cases(87.5%). Pathologic examination confirmed epiphyseal involvement in six of seven cases noted with MR imaging(75%). On the the other hand, in adult patients with closed epiphyseal plates, conventional radiographs showed transphyseal tumor growth in six of eight cases(75%), while MR imaging and pathologic exam demonstrated tumor invasion in all cases(100%). We conclude that open epiphyseal plate does not function as and effective barrier against tumor extension, and MR imaging is an excellent method in detecting the extent of transphyseal tumor growth.
Adult ; Amputation ; Child ; Growth Plate ; Hand ; Humans ; Limb Salvage ; Magnetic Resonance Imaging* ; Methods ; Osteosarcoma* ; Retrospective Studies

To determine the comparative accuracy of two Doppler tests, the findings of 38 patients who had undergone a complete evaluation by supraorbital Doppler test, frontal Doppler test and angiography were studied. When stenosis of 60 percent or more in diameter was considered as a true positive finding, the Doppler tests of 76 internal carotid arteries of the 38 patients showed the following results. Supraorbital Doppler test: eight false positive, three false negative, and 65 correct findings, with an overall accuracy of 85%. The authors, therefore, concluded that the suprorbital Doppler test was more sensitive and accurate than the frontal Doppler test in screening the patients with possible carotid artery occulusive diseases.
Angiography ; Carotid Arteries* ; Carotid Artery, Internal ; Constriction, Pathologic ; Humans ; Mass Screening

Tuberous sclerosis is a rare hereditary anomaly of variable penetrance characterized by mental retardation, epilepsy, and adenoma sebaceum. Pulmonary involvement is uncommon, but, when involve by tuberous sclerosis, it shows characteristic reticulonodular infiltration and cystic changes. Lymphangioleiomyomatosis is a rare disease of unknown cause that affects women of reproductive age. It is characterized by progressive proliferation of smooth muscle in the lung. We experienced one case of pulmonary lymphangioleiomyomatosis associated with tuberous sclerosis in a 26-year-old female patient. This case is reported with a brief of the literature.
Adult ; Angiomyolipoma* ; Epilepsy ; Female ; Humans ; Intellectual Disability ; Lung ; Lymphangioleiomyomatosis* ; Muscle, Smooth ; Penetrance ; Rare Diseases ; Tuberous Sclerosis*

No abstract available.
Ring Chromosomes*

Succinylcholine is commonly administered intravenously, however sometimes it can be administered intramuscularly or sublingually when an intravenous line is not available. We investigated the neuromuscular blocking effect of subcutaneous injection of succinylcholine. The 60 adult patients (ASA 1 or 2) were randomly divided into two groups. After intravenous administration of propofol 3 mg/kg, succinylcholine 1 mg/kg was administered intravenously in one group (IV group, n=10) and subcutaneously in another (SQ group, n=50). Neuromuscular transmission was monitered continuously by the train-of-four (TOF) from response stimulated the ulnar nerve with 2Hz at wrist and the evoked compound action potential of hypothenar muscles was measured with Relaxograph (Datex Co.). We determined the maximum depressed the twitch height (T(TXD)), onset time from injection of succinylcholine to T(MXD), recovery time from T(MXD) to the recovery of 75%, and duration of action from injection of succinylcholine to the recovery of 75%. In the results, T(MXD) of SQ group varied from O% to over 75% compared with 0% in IV group. The onset time of SQ group were more delayed between 7.78+/-2.80 to 13.08+/-3.51 minutes compared with 1.08+/-0.16 minutes in IV group. The recovery time of SQ group were faster between 15.67+/-10.40 to 2.59+/-1.75 minutes compared with 18.68+/-3.68 minutes in IV group. The duration of action of SQ group were not significantly different compared with IV group. And in the SQ group, the lesser depression of twitch height the slower onset time and the faster recovery time was revealed. Conclusively, the subcutaneous administration of succinylcholine 1 mg/kg resulted that the magnitudes of neuromuscular blockade was variable and incomplete, and onset time were slower but recovery were faster than intravenous injection.
Action Potentials ; Administration, Intravenous ; Adult ; Depression ; Humans ; Injections, Intravenous ; Injections, Subcutaneous ; Muscles ; Neuromuscular Blockade* ; Propofol ; Succinylcholine* ; Ulnar Nerve ; Wrist

We investigated fifty four patients with spontaneous intracerebral lobar hemorrhage who were admitted to the Seoul National University Hospital Neurology Sercice during a period of five and a half years. Of these patients 25 (46.3%) had hypertension as the probable cause of hemorrhage Of the remaining cases, 12(22.2%) had other etiologies including 5 arteriovenous malforrnations. 3 aneurysms, 2 tumors, 1 Moyamoya disease and 1 superior sagittal sinus thrombosis, while 14(25.2%) had no apparent etiology. But some of them seemed to be due to cerebral amyloid angiopathy or occult vascular malformation. Parietal region was the most frequent site of hemorrage(23 cases, 42.6%). Six cases had multiple intracerebral hematoma. Common clinical manifestations were headache, vomiting, hemiparesis, seizure in order of frequency. Mortality rate was 16.7%, which was correlated with the size of hematoma (P<0.05) and consciousness level at the initial stage (p<0.05). But not with the presence of intraventricular or subarachnoid hemorrhage. Hypertension or age of onset.
Age of Onset ; Aneurysm ; Cerebral Amyloid Angiopathy ; Cerebral Hemorrhage* ; Consciousness ; Headache ; Hematoma ; Hemorrhage ; Humans ; Hypertension ; Mortality ; Moyamoya Disease ; Neurology ; Paresis ; Rabeprazole ; Seizures ; Seoul ; Subarachnoid Hemorrhage ; Superior Sagittal Sinus ; Thrombosis ; Vascular Malformations ; Vomiting