Radioactive iodine treatment is useful for ablating remnant thyroid tissue and metastasis ofwell-differentiated thyroid cancer withlong-lasting effects. A scintigraphy after radioactive iodine treatment is a major imaging modality for detecting metastasis andassessing the management of metastasis. However, caution is required when reading the scan due to potential false-positivefindings. In this study, scintigraphy and single-photon emission computed tomography/computed tomography images afterradioactive iodine treatment revealed a physiological uptake of radioactive iodine due to lacrimal secretion around an artificialeyeball; such findings have not been reported previously.