1.A case of cyclic neutropenia.
Yoon Hwa CHA ; Hye Sun LEE ; Young Min AHN ; Myoung Sook KOO
Journal of the Korean Pediatric Society 1993;36(7):1009-1015
Cyclic Neutropenia is a benign, unusual hematologic disorder characterized by regularly recurring episodes of severe neutropenia occurring approximately every 21 days. Beside neutrophils, monocytes, lymphocytes, platelets and reticulocytes all cycle with strict periodicity suggest that this disease should be viewed as cyclic hematopoiesis, not merely as cyclic neutropenia. During neutropenic periods, patients regularly experience aphthous stomatitis, fever, malaise, cervical lymphadenitis, cutaneous infections and occasional pneumonia and otitis media. The exact cause of cyclic neutropenia is unknown. But it is strongly suggested that cyclic neurtopenia is due to an abnormality in the regulation of early hematopoietic precursor cells. We have documented a case of cyclic neutropenia for a period of 2.5 years in a 11 year-old boy who had suffered from recurrent fever, stomatitis, gingival swelling, cervical lymphadenitis and skin infections at 3 weeks intervals since 5 years of age. A brief review of the related literatures is presented.
Child
;
Fever
;
Hematopoiesis
;
Humans
;
Lymphadenitis
;
Lymphocytes
;
Male
;
Monocytes
;
Neutropenia*
;
Neutrophils
;
Otitis Media
;
Periodicity
;
Pneumonia
;
Reticulocytes
;
Skin
;
Stomatitis
;
Stomatitis, Aphthous
2.Three cases of type I von Willebrand disease in a family.
Jie Sun YOON ; Hey Sun LEE ; Young Min AHN ; Myoung Sook KOO ; Sun Yang PARK
Journal of the Korean Pediatric Society 1991;34(3):419-425
No abstract available.
Humans
;
von Willebrand Disease, Type 1*
;
von Willebrand Diseases
3.Three cases of type I von Willebrand disease in a family.
Jie Sun YOON ; Hey Sun LEE ; Young Min AHN ; Myoung Sook KOO ; Sun Yang PARK
Journal of the Korean Pediatric Society 1991;34(3):419-425
No abstract available.
Humans
;
von Willebrand Disease, Type 1*
;
von Willebrand Diseases
4.The Effects of Exercise Type on Bone density, Body Fat and Blood Components of the Middle Aged Women.
Korean Journal of Physical Anthropology 1997;10(1):113-123
No abstract available.
Adipose Tissue*
;
Bone Density*
;
Female
;
Humans
;
Middle Aged*
5.Two cases of silicone- induced pulmonary embolism.
Bock Hyun JUNG ; Young Ill SUH ; Jae Myoung LEE ; Sook Hee SONG ; Ho Joong KIM ; Myoung Koo LEE ; In Gyu HYUN ; Ki Suck JUNG ; Hyung Sick SHIN
Tuberculosis and Respiratory Diseases 1993;40(5):610-615
No abstract available.
Pulmonary Embolism*
6.Morphologic Classification of Ductal Breast Tumors on Ultrasound: Differential Diagnosis of Benign and Malignant Tumors.
Mi Sook WON ; Soo Young CHUNG ; Ik YANG ; Yul LEE ; Hai Jung PARK ; Myoung Hwan LEE ; In Sook YOON ; Mi Gyoung KOH
Journal of the Korean Radiological Society 1997;37(2):367-372
PURPOSE: To evaluate the morphologic differential diagnosis of benign and malignant ductal breast tumors, as seen on US. MATERIALS AND METHODS: US findings in 29 pathologically proven cases of ductal breast tumor were retrospectively reviewed. All patients were female and their mean age was 42 years. Nineteen tumors were benign and ten were malignant, and all ductal or cystic lesions showed solid masses. According to the location of the mural nodule, we classified the sonographic appearance of these tumors into three types : intraductal, intracystic and amorphic. The intraductal type was divided into three subtypes: incompletely obstructive, completely obstructive and multiple mural nodules. For the intracystic type, too, three subtypes were designated : the intracystic mural nodule (mural cyst), intracystic mural nodule with the duct (mural cyst+duct) and intracystic multiple mural nodules. The amorphic type is defined as an atypical ductal tumor with the mural nodule extending into adjacent parenchyma. RESULTS: The margin of the duct or cyst was smooth in 68.4% of benign, and irregular in 90% of malignant ductal tumors. Internal echogeneity of the duct or cyst usually showed homogeneity in both benign and malignant tumors. 73.7% of tumors connecting the duct were benign and 50% were malignant. In benign tumors, 52.6% of mural nodule had an irregular margin, while in malignant tumors, the corresponding proportion was 100% ; both types usually showed heterogeneous hypoechogeneity. Among benign tumors, the most common morphologic type was the intraductal incompletely obstructive subtype (36.8%) ; among those that were malignant, the amorphic type was most common, accounting for 40% of tumors. No amorphic type was benign and no incompletely obstructive subtype was malignant. CONCLUSION: When ductal breast tumors are morphologically classified on the basis of sonographic findings, the intraductal incompletely obstructive subtype suggests benignancy, and the amorphic type, malignancy. The morphologic classification of ductal breast tumors based on sonography is therefore useful for the differential diagnosis of benignancy and malignancy.
Breast Neoplasms*
;
Breast*
;
Classification*
;
Diagnosis, Differential*
;
Female
;
Humans
;
Retrospective Studies
;
Ultrasonography*
7.Study on the Temperature Measurement in the Newborn Infants.
Eun Saing JEE ; Young Pyo CHANG ; Jung Hwan CHOI ; Chong Ku YUN ; Yong Ran KIM ; Myoung Sook LEE
Journal of the Korean Pediatric Society 1989;32(12):1632-1636
No abstract available.
Humans
;
Infant, Newborn*
8.Rectal Prolapse Complicated withC lostridium difficile-associated Pseudomembranous Colitis in a Child.
Myoung Sook LEE ; Joon Sung KIM
Keimyung Medical Journal 2014;33(2):136-137
Among the complications of Clostridium difficile (C. difficile) infection, rectal prolapse has been very rarely reported in children. We report a 29-month-old girl who presented with rectal prolapse complicated with C. difficile-associated pseudomembranous colitis following 3-week course of oral amoxicillin/clavulanic acid for treatment of acute otitis media. The patient complained of fever, abdominal pain and mucoid bloody diarrhea. She also showed a protruded and everted rectal mucosa with discrete white-yellowish exudative plaques. Abdominal CT scan revealed a diffuse wall thickening with mucosal enhancement of the rectosigmoid colon. Both stool culture and toxin assay for C. difficile were positive. Her symptoms were completely improved with oral metronidazole treatment. C. diffile-associated pseudomembranous colitis should be considered as a rare but possible cause of rectal prolapse in children who have recently received antibiotic therapy.
Abdominal Pain
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Child*
;
Child, Preschool
;
Clostridium difficile
;
Colon
;
Diarrhea
;
Enterocolitis, Pseudomembranous*
;
Female
;
Fever
;
Humans
;
Metronidazole
;
Mucous Membrane
;
Otitis Media
;
Rectal Prolapse*
;
Tomography, X-Ray Computed
9.A Study on Nursing Equipment Development in Male Patients with Urinary Incontinence.
Ae Ran HWANG ; Eui Sook KIM ; Soon Bok CHANG ; Myoung Ho LEE ; Kyu So KWON ; Young Jae PARK ; In Soon OH
Journal of the Korean Continence Society 1998;2(1):17-28
No abstract available.
Humans
;
Male
;
Nursing*
;
Urinary Incontinence*
10.Ropinirole as an Adjunct to Levodopa in the Treatment of Parkinson's Disease.
Joo Hyuk IM ; Jeong Ho HA ; In Sook CHO ; Myoung Chong LEE
Journal of the Korean Neurological Association 2001;19(2):102-109
BACKGROUND: Ropinirole is a non-ergoline D2 agonist which has a highly selective affinity to D2 receptor. The aim of this study was to evaluate the efficacy and safety of ropinirole in the treatment of Parkinson's disease (PD). METHODS: Seventy-six cases with PD (Hoehn and Yahr stage II to IV) were included in this trial. Each patient was randomly allocated to receive either ropinirole (n=37) or bromocriptine (n=39) over a 16-week period. All subjects were not optimally controlled on levodopa due to motor fluctuations. The response rate was defined as the percentage of patients who had at least 20% reduction of levodopa doses. The clinical status was also assessed using the Unified Parkinson's Disease Rating Scale (UPDRS), Clinical Global Impression (CGI), and reduction of off durations. RESULTS: The end-point analysis, on an intention-to-treat basis, revealed significantly higher response rate in the ropinirole group compared with the bromocriptine group (odds ratio 2.995, 95% C.I. (1.157, 7.751)). A statistically significant improvement in CGI was also observed in the ropinirole group (p=0.046). The mean off duration was significantly reduced in the ropinirole group (p=0.0001). Other parameters using the UPDRS motor score or off duration did not show significant differences between the two groups. The overall incidence of adverse effects was not significantly different between the two groups. The most common side effects were dizziness, dyskinesia, and nausea/vomiting. No subjects were withdrawn from the study due to side effects. CONCLUSION: Ropinirole is a safe and well-tolerated drug and provides superior overall efficacy compared with bromocriptine as an adjunct to levodopa. (J Korean Neurol Assoc 19(2):102~109, 2001)
Bromocriptine
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Dizziness
;
Dyskinesias
;
Humans
;
Incidence
;
Levodopa*
;
Parkinson Disease*