No abstract available.
Enzyme-Linked Immunosorbent Assay* ; Korea*

No abstract available.
Humans ; von Willebrand Disease, Type 1* ; von Willebrand Diseases

No abstract available.
Humans ; von Willebrand Disease, Type 1* ; von Willebrand Diseases

Cyclic Neutropenia is a benign, unusual hematologic disorder characterized by regularly recurring episodes of severe neutropenia occurring approximately every 21 days. Beside neutrophils, monocytes, lymphocytes, platelets and reticulocytes all cycle with strict periodicity suggest that this disease should be viewed as cyclic hematopoiesis, not merely as cyclic neutropenia. During neutropenic periods, patients regularly experience aphthous stomatitis, fever, malaise, cervical lymphadenitis, cutaneous infections and occasional pneumonia and otitis media. The exact cause of cyclic neutropenia is unknown. But it is strongly suggested that cyclic neurtopenia is due to an abnormality in the regulation of early hematopoietic precursor cells. We have documented a case of cyclic neutropenia for a period of 2.5 years in a 11 year-old boy who had suffered from recurrent fever, stomatitis, gingival swelling, cervical lymphadenitis and skin infections at 3 weeks intervals since 5 years of age. A brief review of the related literatures is presented.
Child ; Fever ; Hematopoiesis ; Humans ; Lymphadenitis ; Lymphocytes ; Male ; Monocytes ; Neutropenia* ; Neutrophils ; Otitis Media ; Periodicity ; Pneumonia ; Reticulocytes ; Skin ; Stomatitis ; Stomatitis, Aphthous

No abstract available.
Pulmonary Embolism*

No abstract available.
Arthritis, Infectious* ; Hip Joint* ; Hip*

Lupus anticoagulant (LA) and anticardiolipin antibody (aCL) are circulating immunoglobulins against phospholipids which can result in prothrombotic conditions We present our experience of 45 LA and/or aCL positive stroke patients. I A was tested with a combination of aPTT mixing test, thromboplastin inhibition test, and kaolin clotting time. aCL was measured with ELIZA. There were 33 males and 12 females with their ages ranging from 20 to 76(mean 518) Fifteen patients did not have risk factors for stroke, while 13 had a single, and 17 had multiple risk factors. Hypertension (20 cases) and smoking (14 cases) were the important risk factors while cardiac diseases were found in 9 patients. All patients underwent head CT and/or MRI, which showed multiple infarcts in 18, single infarct in 22, intracerebral hemorrhages in 4, cortical venous infarct in 1 and sagittal sinus thrombosis in 1. Among patients with cerebral infarct, 23 had infarcts in carotid territory, only 7 of whom had large infarcts involving the cerebral cortex. Eleven had strokes in vertebro-basilar territory, and 6 had in both. Overall, 22 patients had relatively small infarcts in carotid territory. Angiogram was performed in 23 patients, which showed normal findings in 14 (most did not have risk factors), internal carotid narrowing or occlusion in 2, proximal MCA narrowing in 2, occlusion of vertebral artery in 1, multiple MCA and ACA occlusion in 1, and venous occlusion in interestingly, one patient showed occlusion of proximal branches of aorta consistent uith Takayasu's disease We conclude that relatively small multiple or single ischemic lnfarcts with negative angiographic findings are the most characteristic findings of antiphospholipid antibody associated stroke, while occasionally observed marked angiographic abnormalities or large cerebral embolic strokes are usually associated with other risk factors Antiphospholipid antibodies seem to play a role in the dlevelopment of cerebrovascular diseases in Korean patients especially in the young age.
Antibodies, Anticardiolipin ; Antibodies, Antiphospholipid* ; Aorta ; Cerebral Cortex ; Cerebral Hemorrhage ; Female ; Head ; Heart Diseases ; Humans ; Hypertension ; Immunoglobulins ; Kaolin ; Lupus Coagulation Inhibitor ; Magnetic Resonance Imaging ; Male ; Phospholipids ; Risk Factors ; Sagittal Sinus Thrombosis ; Smoke ; Smoking ; Stroke ; Thromboplastin ; Vertebral Artery

No abstract available.
Duodenal Ulcer* ; Humans ; Recurrence*

Basal cell adenocarcinoma is an epithelial neoplasm which is cytologically and histomorphologically similar to basal cell adenoma but is different because of the infilitrative growth. This tumor, a rare salivary gland tumor newly classified as basal cell adenocarcinoma by the WHO in 1991, is infiltrative, locally destructive and tends to recur but metastasis is less common. The differential diagnosis includes basal cell adenoma, adenoid cystic carcinoma, and basaloid squamous carcinoma. Nearly 90 percent of these tumors occurr in the parotid gland and can be classified into low grade carcinomas with a relative good prognosis. Basal cell adenocarcinoma of minor salivary gland is very rare and has a less favorable clinical course compared with that of the major salivary glands. This is a case of basal cell adenocarcinoma occurring at the minor salivary gland of the soft palate. We treated this patient with block excision and adjunctive radiation therapy.
Adenocarcinoma* ; Adenoma ; Carcinoma, Adenoid Cystic ; Carcinoma, Squamous Cell ; Diagnosis, Differential ; Humans ; Neoplasm Metastasis ; Neoplasms, Glandular and Epithelial ; Palate, Soft ; Parotid Gland ; Prognosis ; Salivary Glands ; Salivary Glands, Minor*

Wolf-Hirschhorn syndrome is a multiple malformation syndrome associated with mental and developmental retardation, resulting from a deletion at the short arm of chromosome 4 (4p16.3). We report a 11-year-old girl with Wolf-Hirschhorn syndrome, who was presented with severe growth and mental retardation along with characteristic features-frontal bossing, hypertelorism, downslanting of the palpebral fissures and fishlike lips. The diagnosis was confirmed by fluorescent in-situ hybridization (FISH).
Arm ; Child ; Chromosomes, Human, Pair 4 ; Diagnosis ; Female ; Humans ; Hypertelorism ; Intellectual Disability ; Lip ; Wolf-Hirschhorn Syndrome*