96 pupils (age: 17-18)with myopia(not congenital myopia) divided 2 groups. Group 1: 54 pupils: use of Tobicom: 2 tabs/day by oral within 3 months. Group 2: 42 pupils: use of Fish oils 6 tabs/day by oral within 3 months. The results: Group1 have good effect: improved the subjective symptoms and vision, especially slight myopia and newly suffered cases. The drug is well tolerated
Myopia ; Astigmatism ; pupil ; drug therapy

In order to prevent the development of central island after excimer laser photorefractive keratectomy(PRK), 547 eyes which had undergone PRK were studied to evaluate the incidence, width and height of central island retrospectively. Based on this result, PRK was performed on 63 eyes under conventional protocol(software version 3.20, VISX Twenty/twenty Inc, Santa Clara, CA) and then additional laser ablation with a correction amount of 2.5D and adiameter of 3mm was performed whether the incidence has been decreased and additional complications have occurred. As a result of conventional protocol, central island had occurred in 121 eyes out of 547(22.1%) and the width was 2.94+/-0.22mm and the height was 2.64+/-0.89D. In case of 63 eyes which underwent additional laser ablation, central island occurred in 4 eyes (6.34%) and overcorrection occurred only in 3 eyes(4.76%) at one month after PRK. From the standpoint of the above results, we reached the conclusion that the additional ablation for 2.5D by a 3mm in diameter after PRK under conventional protocol is effective. By using this method, we could reduce the incidence of central island without the aid of the upgraded version that contains the anti-central island program.
Incidence ; Laser Therapy ; Lasers, Excimer* ; Myopia* ; Photorefractive Keratectomy* ; Retrospective Studies

OBJECTIVETo observe the therapeutic effect and influential factors of strong stimulation of acupoints around eyes by reducing method of twisting the needle for treatment of adolescent myopia, and to compare the different curative effects of both weak and strong stimulus intensities and wearing glasses in daytime.

METHODSAccording to the principle of knowing and permission, the patients were divided into a strong stimulation group (60 cases, 120 eyes), a weak stimulation group (60 cases, 120 eyes) and a wearing glasses group (60 cases, 120 eyes). Both the strong stimulation group and the weak stimulation group were treated by reducing method of twisting the needle, with Cuanzhu (BL 2), Yuyao (EX-HN 4), Sizhukong (TE 23), Sibai (ST 2) and Taiyang (EX-HN 5) selected. Each acupoint was twisted 360 and 90 times per min for the strong stimulation group, and 90 degrees and 60 times per min for the weak stimulation group; the wearing glasses group were not treated with acupuncture, but with wearing glasses in daytime.

RESULTSAfter treatment with the reducing method of twisting the needle, the vision improved (P < 0.01), with more obviously increased in the strong stimulation group than the weak stimulation group (P < 0.01), and there was no significant change of vision in the wearing glasses group. The age and the myopic degree of the patient before treatment were closely related with the change of vision after treatment (P < 0.01).

CONCLUSIONThe reducing method of twisting the needle has a definite clinical therapeutic effect on adolescent myopia; strong stimulation has a better effect than the weak one; the age and the myopic degree of the patient possibly influence the therapeutic effect.

Acupuncture Points ; Acupuncture Therapy ; methods ; Adolescent ; Child ; Female ; Humans ; Male ; Myopia ; therapy

OBJECTIVETo compare the differences in the efficacy on distant version of naked eye in the patients of juvenile myopia between rotating manipulation and lifting-thrusting manipulation of acupuncture.

METHODSOne hundred and twenty cases (240 eyes) were randomized into a rotating manipulation group and a lifting-thrusting manipulation group, 60 cases (120 eyes) in each group. Additionally, a corrective lenses group, 60 cases (120 eyes), was set up as the control. In both manipulation groups, Cuanzhu (BL 2),Yuyao (EX-HN 4), Sizhukong (TE 23), Taiyang (EX-HN 5), Fengchi (GB 20), Zusanli (ST 36), Guangming (GB 37) and Sanyinjiao (SP 6) were punctured, but stimulated with rotating manipulation and lifting-thrusting manipulation respectively three times per week, 10 times as a treatment session and totally one session was required. In the corrective lenses group, the glasses were applied at daytime. The clinical efficacy and the changes in distant vision of naked eye before and after treatment were compared among the three groups.

RESULTSThe total effective rate was 87.5% (105/120) in the rotating manipulation group, which was better than 69.2% (83/120) in the lifting-thrusting manipulation group (P < 0.05). The distant vision of naked eye was improved apparently in the rotating manipulation group and the lifting-thrusting manipulation group after treatment (both P < 0.05). But it was not improved in the corrective lenses group (P > 0.05). The distant vision of naked eye was improved more apparently after treatment in the rotating manipulation group as compared with that in the lifting-thrusting manipulation group (0.75 +/- 0.23 vs 0.68 +/- 0.24, P < 0.05). For 96 cases (192 eyes) with acupuncture treatment, in 3-month follow-up, 87.0% (167/192) of the cases maintained the stable vision as the original level and 13.0% (25/192) of them were reduced in the vision In the acupuncture groups, it was found that the improvement of distant vision of naked eye was more obvious after treatment with younger age, better basic vision and shorter duration of sickness (all P < 0.05).

CONCLUSIONAcupuncture achieves the positive and sustainable clinical effect on juvenile myopia, and the results of rotating manipulation are superior to that of lifting-thrusting manipulation. Age, basic vision and duration of sickness impact the clinical efficacy.

Acupuncture Points ; Acupuncture Therapy ; instrumentation ; methods ; Adolescent ; Child ; Female ; Humans ; Myopia ; therapy ; Young Adult

OBJECTIVEA systematic review of literature was performed to compare various visual function parameters including the final visual acuity outcome and/or adverse events between corneal refractive surgery (CLRS) and phakic intraocular lens implantation (p-IOLi) in the treatment of refractive amblyopic children.

DATA SOURCESTwo reviewers independently searched the PubMed, EMBASE, and Controlled Trials Register databases for publications from 1991 to 2013.

STUDY SELECTIONThere were 25 articles, including 597 patients and 682 eyes, was included in CLRS group. Among them, 21 articles reported the use of CLRS in the treatment of myopic anisometropia for 318 patients (13 photorefractive keratectomy or laser epithelial keratomileusis and eight laser in situ keratomileusis). And 11 articles had the results of CLRS in treating hyperopic anisometropic amblyopia children. Eleven articles reported the effect of p-IOLi for treating high myopia or anisometropic amblyopia, including 61 patients (75 eyes). Age, pre- and postoperation best-corrected vision acuity (BCVA), and spherical equivalent (SE) were compared in CLRS and p-IOLi groups.

RESULTSThe average age of CLRS group and p-IOLi group has no statistically significant difference. The SE in CLRS group for myopic anisometropia amblyopia patients was (-10.13 ± 2.73) diopters (D) and for hyperopic anisometropia amblyopia patients was (5.58 ± 1.28) D. In p-IOLi group the SE was (-14.01 ± 1.93) D. BCVA was improved significantly in both groups, and even better in p-IOLi group. Refractive errors were corrected in both groups, but there was no clinically significant difference in final SE between each group. More than one-half of the children had improved binocular fusion and stereopsis function in both groups.

CONCLUSIONSBoth CLRS group and p-IOLi group showed their advantage in treating refractive amblyopia in children. In comparing p-IOLi with CLRS for treatment of refractive amblyopia, no statistically significant difference in final BCVA was observed.

Amblyopia ; etiology ; surgery ; therapy ; Anisometropia ; complications ; Child ; Child, Preschool ; Humans ; Myopia ; complications

OBJECTIVETo observe therapeutic effect of electrical plum-blossom needle for treatment of juvenile myopia and biological effect on ocular tissue and structures.

METHODSOne hundred and sixty cases with mild myopia (diopter < 3.00D) were randomly divided into two groups, a treatment group and a control group. The treatment group were treated with electrical plum-blossom needle therapy, tapping Jingming (BL 1), Chengqi (ST 1), Taiyang (EX-HN 5) and Neiguan (PC 6), and the control group with Tropicamide eye drops. The changes of vision, diopter, corneal refractive power, ocular-axial length, lens and ciliaris thickness were observed before and after treatment.

RESULTSThe total effective rate was 80.0% in the treatment group and 58.1% in the control group, with a very significant difference between the two groups (P < 0.01); the two therapies could decrease the thickness of lens and ciliaris, and eliminate spasm of ciliary muscle, however the electrical plum-blossom needle therapy had more obvious action (P < 0.05); the two therapies had no effect on the corneal refractive power and ocular-axial length.

CONCLUSIONThe electrical plum-blossom needle therapy is an effective method for increasing vision, correcting ametropia and delaying development of myopia.

Adolescent ; Child ; Electroacupuncture ; methods ; Female ; Humans ; Male ; Myopia ; physiopathology ; therapy ; Refraction, Ocular ; Vision, Ocular

Myopia studies are notoriously difficult to carry out. Past studies on intervention in myopia progression have given conflicting results. Beside inaccurate and inadequate measurements, the most important cause for this is the very variable nature of myopia, which makes it difficult to achieve baseline comparability between the control and the study group. Although there were inclusion criteria in these studies, for age, sex, race, degree of myopia and stigmatism, the most important variate-- the rate of myopia progression-- was not included. Randomisation can achieve baseline comparability of the myopia progression rate, provided the sample sizes are large enough. Unfortunately, past studies have been limited to 100 to 200 children only. Studies on twins are more reliable than random groups because myopia progression rates are more likely to be the same in a pair of twins. Studies on the same subject, comparing the right eye and the left eye would be even better, but this method is practicable for some studies only (e.g., we cannot have a spectacle lens for one eye and a contact lens on the fellow eye). There is another method of doing an interventional study on myopia. Because myopia progression is linear in its early stage until the early teenage years, it is possible to observe what happens to the linear progression upon intervention. In this way, we avoid the problem of trying to compare "apples with apples" but use the "same apple" instead.
Contact Lenses ; Disease Progression ; Humans ; Myopia ; pathology ; therapy ; Randomized Controlled Trials as Topic ; methods ; Reproducibility of Results ; Research

OBJECTIVE: To evaluate the change in accommodative lag and accommodation convergence/accommodation (AC/A) after patients with myopia wear orthokeratology lenses. 
 METHODS: A total of 48 myopic subjects (a test group), who wore orthokeratology lenses regularly, and 48 myopic subjects (a control group), who wore spectacles regularly, were enrolled for this study from January 2011 to January 2013 in Optometric Center, the Forth Hospital of Changsha. Accommodative lag was measured by fused cross cylinder method, where the patients should gaze at the front optotypes 40 cm away. Gradient of the AC/A ratio was measured by Von Grafe method to check closer distance heterophoria. Accommodative lag and AC/A ratio were analyzed by statistics.
 RESULTS: After 1-year follow-up, accommodative lag and AC/A rate in patients with low or moderate myopia in the test group was decreased in 1, 3, 6 months or 1 year compared with that in the control group (P<0.05). 
 CONCLUSION Compared with spectacles, orthokeratology lenses are able to decrease accommodative lag and high AC/A rate in patients with low or moderate myopia. The relationship between accommodation and convergence is improved by orthokeratology lenses. Orthokeratology is an effective way to control myopia.
Accommodation, Ocular ; Case-Control Studies ; Contact Lenses ; Eyeglasses ; Humans ; Myopia ; therapy ; Orthokeratologic Procedures ; Strabismus

PURPOSE: We evaluated ocular optical components and their interrelationships in myopic Korean patients. METHODS: In this prospective observational study, 1,011 consecutive patients were recruited from a refractive surgery clinic. The best-corrected visual acuity was >20 / 20 in all patients. The refractive error, axial length (AL), anterior chamber depth (ACD), lens thickness (LT), and vitreous chamber depth (VCD) were measured by an autorefractor and partial coherence laser interferometry (IOL Master). Central corneal thickness (CCT) was measured by ORBscan II topography. RESULTS: The refractive errors had a positive correlation with LT but negative correlations with AL, ACD, VCD, and CCT. As the axial length increased, the ACD, VCD, and CCT increased but the LT decreased. The CCT had a positive correlation with gender, refractive errors, ACD, VCD, and AL but no correlation with age. The mean CCT was increased in proportion to the increase in AL. CONCLUSIONS: In myopic Korean patients, as axial elongation progressed, the VCD and ACD deepened and the CCT thickened but the LT decreased. The CCT had a positive correlation with the degree of myopia and the AL.
Adult ; Female ; Humans ; Male ; Middle Aged ; Myopia/*epidemiology/therapy ; Prospective Studies ; Refractive Errors/*epidemiology/therapy ; Republic of Korea/epidemiology ; Visual Acuity

We report a case of one sister and brother with mirror image myopic anisometropia. One sister and brother complained visual disturbance. The sister was 10 years 11 months old, and brother was 8 years 4 months old. Full ophthalmic examinations were performed, including slit lamp examination, intraocular pressure, keratometry, anterior chamber depth, axial length, fundus examination and the cycloplegic refraction. The cycloplegic refractive power was -15.50 dpt cyl.+4.50 dpt Ax 85degrees (right eye), -1.00 dpt cyl.+0.50 dpt Ax 90degrees (left eye) in the sister; -1.75 dpt cyl.+2.25 dpt Ax 90degrees (right eye), -9.50 dpt cyl.+4.00 dpt Ax 80degrees (left eye) in the brother. The co-occurrence of severe myopic anisometropia in a sister and brother is extremely rare. The present case suggests that severe myopic anisometropia may be related by genetic inheritance.
Anisometropia/*etiology/*genetics/physiopathology/therapy ; Child ; Female ; Humans ; Male ; Myopia/*complications/*genetics/physiopathology/therapy ; Refraction, Ocular ; *Siblings ; Visual Acuity