PURPOSE: To assess the efficacy of the Toric Implantable Collamer Lens (Toric ICL) to treat moderate to high myopic astigmatism. METHODS: Toric ICL was implanted in 77 eyes of 40 patients with myopia (spherical equivalent [SE] between 3.5 and 18.5 diopters [D]) and astigmatism between 1 and 6 D. The patients were followed up for at least 3 months. Uncorrected visual acuity (UCVA), refraction, best spectacle-corrected visual acuity (BSCVA), adverse events, and postoperative complications were evaluated. RESULTS: At 3months postoperatively, the proportion of eyes with 1.0 or better UCVA (56 eyes out of 77 eyes, 72.7%) was significantly greater than the proportion of eyes with preoperative 1.0 or better BSCVA (38 eyes out of 77 eyes, 49.4%). The mean manifest refractive cylinder dropped from 2.78D (+/-1.05) at baseline to 0.35D (+/-0.34) postoperatively, an 87.4% decrease in astigmatism. Mean manifest refraction SE (MRSE) improved from -9.93D (+/-2.66) preoperatively to 0.15D (+/-0.33) postoperatively. A total of 96.1% of eyes were predicted accurately to within +/-0.75D of predicted MRSE. Mean improvement in BSCVA was 0.79lines; there were no eyes that lost two lines of BSCVA after 3 months postoperatively. CONCLUSIONS: The results support the efficacy and predictability of Toric ICL implantation to treat moderate to high myopic astigmatism.
Astigmatism ; Eye ; Humans ; Myopia ; Postoperative Complications ; Visual Acuity

PURPOSE: To compare the results of transepithelial photorefractive keratectomy (trans PRK) and brush-assisted photorefractive keratectomy (brush PRK) for the treatment of myopia. METHODS: A total of 146 eyes from 78 patients who received brush PRK or trans PRK with the Schwind Amaris laser platform were included in the present study. Uncorrected distance visual acuity (UDVA) and manifest refraction spherical equivalent (MRSE) at postoperative 1 week, 1, 3, 6, and 12 months were compared between the 2 groups as well as epithelial healing time. RESULTS: The mean time to complete epithelial healing was 3.27 +/- 0.75 days in the trans PRK group and 3.67 +/- 0.93 days in the brush PRK group (P < 0.05). At 1 week after surgery, UDVA recovered more rapidly after trans PRK than brush PRK (brush PRK: 0.13 +/- 0.12 log MAR units, trans PRK: 0.09 +/- 0.08 log MAR units, P < 0.05), however, UDVA was not significantly different at 1, 3, 6, and, 12 months postoperatively between the 2 groups. CONCLUSIONS: Re-epithelialization and visual recovery were faster in the trans PRK group while visual outcome and postoperative complications were equivalent to the brush PRK group.
Humans ; Myopia ; Photorefractive Keratectomy* ; Postoperative Complications ; Re-Epithelialization ; Visual Acuity

PURPOSE: To evaluate the clinical outcomes of small incision lenticule extraction (SMILE) for the treatment of myopia with corneal opacity. METHODS: Thirteen eyes of 13 patients with corneal opacities who underwent SMILE were retrospectively studied. Uncorrected distance visual acuity, spherical equivalence, efficacy index, and safety index were noted at 3 months after the procedure. The density and area of the corneal opacities were measured and compared preoperatively and 3 months postoperatively. RESULTS: All eyes had preoperative corneal opacities within the lenticule formation areas. The mean area and density of corneal opacities were 0.72 ± 0.33 mm2 and 52.46 ± 15.74, respectively. All procedures were uneventful and no intraoperative complications were observed. At 3 months after the procedure, the efficacy and safety indices were 1.01 ± 0.15, and 1.05 ± 0.10, respectively, and the mean densities and areas of corneal opacities were 46.85 ± 14.56 (p = 0.038) and 0.70 ± 0.36 mm2 (p = 0.776), respectively. CONCLUSIONS: The SMILE procedure was effective and safe for the correction of myopic patients with corneal opacities.
Corneal Opacity ; Humans ; Intraoperative Complications ; Myopia ; Retrospective Studies ; Visual Acuity

We evaluated clinical results and complications of LASIK using Technolas 217 C-LASIKTM excimer laser. This study included 102 patients(203 eyes) who had LASIK from March 1998 to February 1999 and followed up for at least 6months. Preoperative mean spherical equivalent was -3.99+/-1.198(SD), -7.928+/1.138(SD)and -11.92+/-1.060(SD)in each group I, II, III.The results at postoperative 6months were as following: 1. Mean spherical equivalent was -0 .44+/-0.410(SD), -0.34+/-0.500(SD), -0.37+/-0.430(SD)in each group I, II, III. 2. The 70 eyes(65%), 48 eyes(61%), 10 eyes(60%)in each group I, II, III were within+/-0.5D. 3. Mean uncorrected visual acuitywas 1.00+/-0.130(SD), 0.96+/-0.140(SD), 0.86+/-0.150(SD)in each group I, II, III. 4. Loss of best spectacle corrected visual acuity of two or more lines was 6 eyes(3%). Intraoperative complications was thin flap(5 eyes, 2.5%), flap tear(1 eyes, 0.5%)and postoperative complications was night glare and halo(58 eyes, 28.8%), punctate epithelial keratopathy(35 eyes, 12.3%)and interface foreign body(23 eyes, 11.3%). Above results suggests that myopic keratomileusis using Technolas 217 C-LASIKTM is a safe, effective way to correct myopia.
Glare ; Intraoperative Complications ; Keratomileusis, Laser In Situ* ; Lasers, Excimer ; Myopia ; Postoperative Complications ; Visual Acuity

OBJECTIVEA systematic review of literature was performed to compare various visual function parameters including the final visual acuity outcome and/or adverse events between corneal refractive surgery (CLRS) and phakic intraocular lens implantation (p-IOLi) in the treatment of refractive amblyopic children.

DATA SOURCESTwo reviewers independently searched the PubMed, EMBASE, and Controlled Trials Register databases for publications from 1991 to 2013.

STUDY SELECTIONThere were 25 articles, including 597 patients and 682 eyes, was included in CLRS group. Among them, 21 articles reported the use of CLRS in the treatment of myopic anisometropia for 318 patients (13 photorefractive keratectomy or laser epithelial keratomileusis and eight laser in situ keratomileusis). And 11 articles had the results of CLRS in treating hyperopic anisometropic amblyopia children. Eleven articles reported the effect of p-IOLi for treating high myopia or anisometropic amblyopia, including 61 patients (75 eyes). Age, pre- and postoperation best-corrected vision acuity (BCVA), and spherical equivalent (SE) were compared in CLRS and p-IOLi groups.

RESULTSThe average age of CLRS group and p-IOLi group has no statistically significant difference. The SE in CLRS group for myopic anisometropia amblyopia patients was (-10.13 ± 2.73) diopters (D) and for hyperopic anisometropia amblyopia patients was (5.58 ± 1.28) D. In p-IOLi group the SE was (-14.01 ± 1.93) D. BCVA was improved significantly in both groups, and even better in p-IOLi group. Refractive errors were corrected in both groups, but there was no clinically significant difference in final SE between each group. More than one-half of the children had improved binocular fusion and stereopsis function in both groups.

CONCLUSIONSBoth CLRS group and p-IOLi group showed their advantage in treating refractive amblyopia in children. In comparing p-IOLi with CLRS for treatment of refractive amblyopia, no statistically significant difference in final BCVA was observed.

Amblyopia ; etiology ; surgery ; therapy ; Anisometropia ; complications ; Child ; Child, Preschool ; Humans ; Myopia ; complications

OBJECTIVETo investigate the incidence of myopic retinopathy and its risk factors.

METHODSThe fundus of 1449 patients (2879 eyes) with myopia were retrospectively examined. The clinical relationship between myopic retinopathy and diopter, age, and sex was analyzed.

RESULTSMyopic retinopathy was detected in 413 eyes (14.35%). Posterior pole retinal lesions were detected in 22 eyes (0.76%). Peripheral retinal lesions were found in 396 eyes (13.75%). According to their diopters, the myopic patients were divided into four groups: low, medium, high and super high myopia The incidence of peripheral retinal lesions was 4.18%, 8.72%, 19.18%, and 37.44% in these four groups, which significantly different (chi2 = 178.594, P<0.001). By age these patients were divided into three groups: I group, age <25; II group, age 25-34; III group, age >34. The incidences of peripheral retinal lesions in these three groups were 8.11%, 15.34%, and 24.59%, which were significantly different (chi2 = 76.090, P<0.001). The incidence of retinal lesion in male and female was 9.32% and 16.07%, respectively, which was significantly different (chi2 = 24.886, P<0.001). Posteriorpole retinal lesions were only detected in the highly or super highly myopic patients, all of them were more than 25 years. The incidence of posteriorpole retinal lesions in the highly and super highly myopia group was 0.86% and 6.67% respectively, which was significantly different (chi2 = 31.898, P<0.001). The incidence of posteriorpole retinal lesions in group II and group III was 0.55% and 3.55% respectively, which was significantly different (chi2 = 22.523, P<0.001).

CONCLUSIONSThe prevalence of retinal lesions in myopic patients is higher than that of emmetropia. The incidence of peripheral retinal lesions increases in patients with deeper diopters. Posterior pole retinal lesions usually occur in the myopic patients whose age are more than 25 years and diopter more than - 6.00 D. Careful examination of fundus is essential for early detection and timely treatment.

Adult ; Female ; Humans ; Male ; Myopia ; complications ; Retina ; pathology ; Retinal Diseases ; complications ; pathology ; Retrospective Studies ; Young Adult

Strabismus fixus is very rare and the convergent form is rarely accompanied by blepharoptosis. We successfully treated one patient with high myopia whose convergent strabismus fixus, accompanied by blepharoptosis, became severe after cataract surgery. We report the case with a discussion of its pathology. We performed levator advancement operation, bilateral lateral rectus 11 mm resection, and bilateral medial rectus 8 mm recession. The suture was removed after maintaining temporary traction suture for 6 days. Blepharoptosis was completely corrected by postoperative 2 months. Esodeviation was 15PD, which was not increased compared with immediately after surgery. Satisfactory cosmetic outcome was obtained.
Aged ; Blepharoptosis/complications/*surgery ; Female ; Humans ; Myopia/complications ; Oculomotor Muscles/*surgery ; Ophthalmologic Surgical Procedures/methods ; Strabismus/complications/*surgery ; Treatment Outcome

PURPOSE: Cornelia de Lange syndrome is a rare disease showing characteristic facial appearance, developmental delay, growth retardation, low birth weight, skeletal formation anomaly, hirsutism and various ophthalmologic problems. METHODS: We experienced a case of an 18-year-old female with Cornelia de Lange syndrome showing superficial keratitis with entropion, ptosis, high myopia, lacrimal cutaneous fistula and characteristic facial appearance. She was born with low birth weight, operated for cleft palate and diagnosed with ventricular septal defect. In addition, she showed psychological lag and developmental impairment. RESULTS: We performed entropion correction surgery, administered medical therapy for superficial keratitis and prescribed glasses for her myopia. CONCLUSIONS: This is the first case report on the successful correction of entropion with Cornelia de Lange syndrome in Korea.
Adolescent ; *Asian Continental Ancestry Group ; Blepharoptosis/*complications ; De Lange Syndrome/*complications/*ethnology ; Entropion/*complications/surgery ; Eyeglasses ; Female ; Humans ; Keratitis/*complications/drug therapy ; Myopia/*complications/therapy

Korean hemorrhagic fever is an acute febrile illness which causes hemorrhagic nerrosis of multiple internal organs. Some orular symptoms are described by physicians without ophthalmic examination. The authors evaluated early ocular manifestations in 21 patients (42 eyes) with Korean hemorrhagic fever, who were admitted from Oct. to Nov. in 1984. The results are summarized as follows: 1. In eleven patients (22 eyes, 52.4%), visual disturbances caused by transitory myopia were observed. 2. During the period of transitory myopic change, the intraocular pressure in the group of refrartive change was significantly raised compared to that in the group of non-refrartive change. 3. In the group of refractive change, increasing intraocular pressure and a shallowing of the anterior chamber were observed accompanied by transitory myopic change. 4. During the earIy phase of the illness, lid edema, chemosis, conjunctival injection, subconjunctival hemorrhage, and macular edema were observed.
Eye Diseases/etiology ; Eyelid Diseases/etiology ; Hemorrhagic Fever with Renal Syndrome/*complications ; Humans ; *Intraocular Pressure ; Myopia/*etiology

PURPOSE: The authors evaluated the clinical results, the degree of satisfaction regarding daily activities and the quality of life after clear lens extraction in high myopes. METHODS: Thirty nine eyes of 23 high myopes over minus 10 diopters underwent clear lens extraction and had minimum follow up of 3 months. The preoperative and postoperative refractive status and subjective satisfaction about surgical result were evaluated. The average follow up period was 10.4 months. (range, 3~24 months) RESULTS: Preoperative mean spherical equivalent and mean target refractive error were -17.40+/-4.00D (range, -11.25~-28.25D) and -1.40+/-0.46D (range, -0.3~-2.2D), respectively. Three months postoperatively, mean spherical equivalent was -1.64+/-0.96D (range, +0.5~-3.62 D). Three months postoperatively uncorrected visual acuity was compared with preoperative best spectacle corrected visual acuity. Visual acuity was decreased two lines or more in 4 eyes (10.3%) and in 23 eyes (59.9%) 20/20 was noted or visual acuity increased 2 lines or more. Posterior capsular opacification (PCO) was noted in 12 eyes (30.8 %) and was the most common postoperative complication within 3 months. Three months postoperatively, every patient was asked about their satisfaction of surgery. All except one patient were satisfied with their daily activities after surgery. and all patients except two complained of difficulty in near vision. CONCLUSIONS: The clear lens extraction can improve quality of life in extremely high myopes, but posterior capsular opacity and decreased near visual acuity should be considered in deciding surgery.
Follow-Up Studies ; Humans ; Myopia* ; Postoperative Complications ; Quality of Life ; Refractive Errors ; Visual Acuity