No abstract available.
Lymphoma, Non-Hodgkin*

No abstract available.
Child* ; Humans ; Infant* ; Intussusception*

Subcutaneous fat necrosis of the newborn is an uncommon disorder which is characterized by multiple erythematous subcutaneous nodules and plaques appearing in the first week to a month of life. The chief precipitating factors presumably concerned in this disease are obstetric trauma, anoxia and cold exposure. We observed a case of subcutaneous fat necrosis of the newborn in which intrauterine asphyxia and preeclampsia had occured.
Anoxia ; Asphyxia ; Humans ; Infant, Newborn* ; Necrosis* ; Pre-Eclampsia ; Precipitating Factors ; Subcutaneous Fat*

BACKGROUND AND OBJECTIVES: Raman spectroscopy is a vibrational spectroscopic technique capable of providing details on the chemical composition, molecular structure and molecular interactions in cells and tissues. Its application of distinguishing normal and cancer tissue has been studied in a variety of sites, such as the cervix, lung, larynx and skin. The purpose was to explore spectral changes between normal and cancer tissue in the larynx using Raman spectroscopy to assess the feasibility of using Raman spectroscopy for the early diagnosis of laryngeal cancer. MATERIALS AND METHOD: Laryngeal tissue specimens (13 adjacent normal and 13 cancer tissues) were obtained from patients who underwent total laryngetomy or supracricoid laryngectomy with squamous cell carcinoma of the larynx. The specimens were stored -70 degrees C until use. These specimens were defrosted at room temperature. The Raman spectra from laryngeal tissue specimens could be obtained at 300 mW and 250 scan during 15 minutes of the signal acquisition time using FT-Raman spectroscopy (Bruker Co., Karsruhe, Germany). RESULTS: Raman spectra were different significantly between cancer and adjacent normal tissues of the larynx at 1446 cm-1, 1240 cm-1, 1335 cm-1, and 1655 cm-1 (p=0.007, 0.2, 0.2, 0.3, respectively). The difference of 1446 cm-1 means the change of CH2 bending mode in protein and lipid of malignant tissue. The change of 1335 cm-1 means a decrease in CH3CH2 to a wagging mode of collagen and polynucleotide chain of malignant tissue. The difference of 1240 and 1655 means a decrease in the alpha-helix conformation of collagen. CONCLUSION: This study demonstrates the differences of Raman units between laryngeal cancer and adjacent normal tissue using Raman spectroscopy. In future, Raman spectroscopy may become a useful tool of guided biopsy for accurate pathologic diagnosis and assessment of the adequacy of resection margins.
Biopsy ; Carcinoma, Squamous Cell ; Cervix Uteri ; Collagen ; Diagnosis ; Early Diagnosis ; Female ; Humans ; Laryngeal Neoplasms ; Laryngectomy ; Larynx* ; Lung ; Molecular Structure ; Skin ; Spectrum Analysis ; Spectrum Analysis, Raman*

No abstract available.
Hand* ; Humans

No abstract available.
Humans ; Infant, Newborn* ; Mothers* ; Thrombocytopenia

OBJECTIVE: Major depression is known to have immunologic dysfunctions, the recent studies revealed that cytokines including Il-6 and IL-1beta were increased in patients with major depression. Since molecular genetic methods have been progressed, this study was to investigate the relationship between major depression and immunologic aspects by analyzing polymorphism of IL-10 gene. METHOD: 92 patients with major depression were included and data of 146 normal controls obtained from the Catholic Hemopoietic Stem Cell Information Bank of Korea were used in this study. DNA was extracted from whole blood, thereafter amplified by polymerase chain reaction, and digested by Mae III. After that procedure, we obtained and assessed RFLP of two alleles, IL-10T and IL-10C. All data were analyzed by chi2 test. RESULTS: 1) There were no significant difference in genotype frequencies of IL-10*T/T, IL-10*T/C, and IL-10*C/C between major depression patients group and control group. 2) There were no significant difference in allelic frequencies of IL-10*T and IL-10*C between major depression patients group and control group. CONCLUSION: We did not verified the differences in frequencies of IL-10*T/IL-10*C gene between the major depression patients group and control group, respectively. But the results of this study do not declare that the IL-10 gene has no association with major depression. We do suggest that further systematic studies including various clinical variables should be conducted.
Alleles ; Cytokines ; Depression* ; DNA ; Genotype ; Humans ; Interleukin-10* ; Interleukin-6 ; Korea ; Molecular Biology ; Polymerase Chain Reaction ; Polymorphism, Restriction Fragment Length* ; Stem Cells

In the East, Probably one of the most commonly performed esthetic operation is the piercing of the earlobes for earring. the complication of this procedure includes infection, the formation of the hypertrophic scar or keloid, and tearing. Keloid formation is one of the disaterous common complications of the ear piercing. the patients regard the keloid as a cosmetic blemish and they complain that they cannot wear earrings. We have experienced 5 patients of earlobe keloid complicated from piercing of the earlobes. We used intralestional steroid njection, in conjunction with surgical excision and pressure therapy for treatment of the keloid. Among various techniques for reconstructing a piercing, we chose modified Pardue's method for artificial earlobe cleft after wide excision of the keloid. the result was good and satisfactory without any complication after 4 to 24 months of follow-up. the purpose of this paper is to present a simple method of treatment of the earlobe keloid with preservation of the perforation for an earring.
Body Piercing ; Cicatrix, Hypertrophic ; Ear* ; Follow-Up Studies ; Humans ; Keloid*

No abstract available.
Glycopyrrolate* ; Salivary Glands* ; Scopolamine Hydrobromide*

No abstract available.
Electroconvulsive Therapy* ; Prolactin*