No abstract available.
Antibodies* ; Chungcheongnam-do* ; Diagnosis* ; Immunoglobulin G* ; Immunoglobulin M* ; Orientia tsutsugamushi* ; Rickettsia* ; Scrub Typhus*

No abstract available.
Antibodies* ; Chungcheongnam-do* ; Diagnosis* ; Immunoglobulin G* ; Immunoglobulin M* ; Orientia tsutsugamushi* ; Rickettsia* ; Scrub Typhus*

To understand the seroepidemiological patterns of haemorrhagic fever with renal syndrome in Korea, a nation-wide survey collaborated with fourteen clinics was carried out from 1994 to 1996. Sera of 4,547 patients with acute febrile episodes were tested by indirect immunofluorescent antibody test and the seroepidemiological analysis including sex, age, seasonal and regional distributions were performed. According to the results obtained in this study, the epidemiological characteristics of haemorrhagic fever with renal syndrome in Korea were summarized as follows: 1. Seropositive rate of hemorrhagic fever with renal syndrome among the patients with acute febrile episodes was 6.4% by the cut-off point of 1:40. 2. Among the seropositives, male outnumbered female and the ratio of males to females was 2.0:1.0. 3. Seventy six % of the seropositive patients were 21-60 years old. 4. The number of seropositive cases increased from October and reached maximum in December and began to decrease gradually from January. 5. The geographical distribution of the seropositives cover most areas including Cheju province in Korea.
Female ; Fever ; Hemorrhagic Fever with Renal Syndrome* ; Humans ; Jeju-do ; Korea* ; Male ; Seasons

PURPOSE: In the past days, the majority of 2nd degree burns were treated conservatively, and deep 2nd degree burns were usually covered by skin grafts. However, conservative treatment spends a long time in complete healing and accompanies severe pain and discomfort. Additionally, covering the wound with skin graft causes recipient site scarring and donor site morbidity. Since keratinocyte graft was introduced, nowadays it is widely used in burn wound. These treatment methods are proved to be clinically successful by many clinical and experimental studies. However, there are several disadvantages such as inconvenient using methods and limited usage in several cases. For that reason, at 2004, alloplastic material was first introduced to come over these problems of keratinocyte graft. There had been no precious reports comparing theses two methods, so we planned to focus on differences of two methods in our institute. METHODS: From March 2013 to september 2014, among the 47 patients with burn wound (2nd degree - partial 3rd degree) underwent biologic dressing with cultured keratinocyte allograft (Kaloderm(R) (Tegoscience, Korea)) alloplastic material (Suprathel(R) (Polymedics Innovations GmbH, Germany). The outcomes were assessed using time for epithelization, TBSA (%), Vancouver Scar Scale and complication. RESULTS: All burn wounds were completely epithelized without any complication. The average time for epithelization was 13.4/13.4 days. CONCLUSION: The result of this study suggests that Kaloderm(R) and Suprathel(R) did not show significant difference. Therefore, Suprathel(R) may be considered as an alternative choice for treating 2nd and 3rd degree burns in some clinical settings.
Allografts* ; Biological Dressings ; Burns* ; Cicatrix ; Humans ; Keratinocytes* ; Skin ; Tissue Donors ; Transplants ; Wounds and Injuries

Traumatic cleft earlobes are a common problem encountered by plastic and reconstructive surgeons. Various techniques have been reported for the repair of traumatic cleft earlobes. Usually, the techniques of split earlobe repair are divided into two categories, namely straight- and broken-line repairs. Straight-line repair is simple and easy, but scar contracture frequently results in notching of the inferior border of the lobule. It can be avoided by the broken-line repair such as Z-plasty, L-plasty, or a V-shaped flap. Between April 2016 and February 2017, six patients who presented with traumatic cleft earlobe underwent surgical correction using a combination of the inverted V-shaped excision technique and vertical mattress suture method. All the patients were female and had a unilateral complete cleft earlobe. No postoperative notching of the inferior border the lobule occurred during 6–16 months of follow-up. Without the use of a broken-line repair, both the patients and the operators attained aesthetically satisfactory results. Therefore, the combination of the inverted V-shaped excision technique and vertical mattress suture method is considered useful in the treatment of traumatic cleft earlobes.
Cicatrix ; Contracture ; Ear ; Female ; Follow-Up Studies ; Humans ; Methods* ; Plastics ; Surgeons ; Suture Techniques ; Sutures*

Traumatic cleft earlobes are a common problem encountered by plastic and reconstructive surgeons. Various techniques have been reported for the repair of traumatic cleft earlobes. Usually, the techniques of split earlobe repair are divided into two categories, namely straight- and broken-line repairs. Straight-line repair is simple and easy, but scar contracture frequently results in notching of the inferior border of the lobule. It can be avoided by the broken-line repair such as Z-plasty, L-plasty, or a V-shaped flap. Between April 2016 and February 2017, six patients who presented with traumatic cleft earlobe underwent surgical correction using a combination of the inverted V-shaped excision technique and vertical mattress suture method. All the patients were female and had a unilateral complete cleft earlobe. No postoperative notching of the inferior border the lobule occurred during 6–16 months of follow-up. Without the use of a broken-line repair, both the patients and the operators attained aesthetically satisfactory results. Therefore, the combination of the inverted V-shaped excision technique and vertical mattress suture method is considered useful in the treatment of traumatic cleft earlobes.
Cicatrix ; Contracture ; Ear ; Female ; Follow-Up Studies ; Humans ; Methods* ; Plastics ; Surgeons ; Suture Techniques ; Sutures*

No abstract available.
Ear Canal* ; Keratosis, Seborrheic*

BACKGROUND AND OBJECTIVES: Sudden deafness in the elderly is rare and its prognosis is poorer than in adults. The unaffected ear also may have hearing impairment of variable severity and physiological hearing threshold shift termed presbycusis in the elderly. The old person often had various systemic complications including diabetes and hypertension. This study was designed to evaluate clinical manifestations and prognosis of sudden deafness in the elderly and to compare with sudden deafness in adults and children. SUBJECTS AND METHOD: We reviewed the medical and audiological records of 96 patients (102 ears) who are more than 60 years of age, and admitted to the Department of Otolaryngology, Pusan National University Hospital from January 1990 to December 2001. RESULTS: The total recovery rate of sudden deafness was lower in the elderly than in adults and children. Hearing recovery was significantly poorer in the patients with diabetes and hypertension. Hearing recovery was significantly poor in the patients with profound degree of hearing loss. The patients who had been treated within 7 days after onset of hearing loss showed better recovery rate than those treated 7 days later. CONCLUSION: We consider the effect of treatment of sudden deafness in the elderly to be best judged in various degrees of hearing impairment in the unaffected ear. The poor prognosis observed in patients with the concurrent disease is likely to have been brought about by preexisting microvascular diseases of the hearing organ, which is highly affected by aging. Good hearing recovery in the elderly is considered to be associated with time of initial treatment and expected in patients without concurrent diseases.
Adult ; Aged* ; Aging ; Busan ; Child ; Ear ; Hearing ; Hearing Loss ; Hearing Loss, Sudden* ; Humans ; Hypertension ; Otolaryngology ; Presbycusis ; Prognosis

Twenty-four monoclonal antibodies were produced by immunizing BALB/c mice with Rickettsia tsutsugamushi Boryong strain and used for the analysis of antigenic characteristics of R.tsutsugamushi Boryong strain and antigenic heterogeneity of R.tsutsugamushi by indirect immunofluorescent(IF) test. R. tsutsugamushi Kato, Karp, Gilliam, TA686, TA716, TA763, TC586, TH1817, and Boryong were used for the analysis of antigenic heterogeneity of R.tsutsugamushi. Five monoclonal antibodies were reactive with 27-kDa protein, four monoclonal antibodies were reactive with 47-kDa protein, and eight monoclonal antibodies were reactive with 56-kDa protein of R.tsutsugamushi Boryong strain. The reactive protein of seven monoclonal antibodies could not be identified by immunoblotting method. All monoclonal antibodies to 27-kDa protein and three monoclonal antibodies to 47-kDa protein, and five monoclonal antibodies to 56-kDa protein were reactive with three to eight strains among nine strains of R. tsutsugamushi tested. One monoclonal antibody reactive to 47-kDa protein(KI18) and two monoclonal antibodies reactive to 56-kDa protein(KI36, and KI37) reacted with all the strains of R. tsutsugamushi tested. Strain-specific monoclonal antibody(KI58) could be found among antibodies which were reactive with 56-kDa protein. There was no strain which showed same reactivity pattern to these 24 monoclonal antibodies among nine strains. From this results, it could be concluded that Boryong strain is antigenically different from other strains of R.tsutsugamushi and antigenic heterogeneity of R.tsutsugamushi is due to the antigenic diversity of several proteins of R. tsutsugamushi including 56-kDa protein.
Animals ; Antibodies, Monoclonal/*immunology ; Antigens, Bacterial/*analysis ; Bacterial Proteins/analysis ; Mice ; Mice, Inbred BALB C ; Orientia tsutsugamushi/*immunology ; Species Specificity

A thermal neutron beam facility utilizing a typical tangential beam port for Neutron Capture Therapy was installed at the HANARO, 30 MW multi-purpose research reactor. Mixed beams with different physical characteristics and relative biological effectiveness would be emitted from the BNCT irradiation facility, so a quantitative analysis of each component of the mixed beams should be performed to determine the accurate delivered dose. Thus, various techniques were applied including the use of activation foils, TLDs and ionization chambers. All the dose measurements were performed with the water phantom filled with distilled water. The results of the measurement were compared with MCNP4B calculation. The thermal neutron fluxes were 1.02E9 n/cm2 s and 6.07E8 n/cm2 s at 10 and 20 mm depth respectively, and the fast neutron dose rate was insignificant as 0.11 Gy/hr at 10 mm depth in water. The gamma-ray dose rate was 5.10 Gy/hr at 20 mm depth in water. Good agreement within 5%, has been obtained between the measured dose and the calculated dose using MCNP for neutron and gamma component and discrepancy with 14% for fast neutron flux. Considering the difficulty of neutron detection, the current study support the reliability of these results and confirmed the suitability of the thermal neutron beam as a dosimetric data for BNCT clinical trials.
Fast Neutrons ; Neutron Capture Therapy* ; Neutrons* ; Relative Biological Effectiveness ; Water