Candida infections after total knee replacement are extremely rare and show no specific symptoms and signs, thus make it difficult to diagnose. It is desirable to perform fungi culture from the beginning in case of persistent swelling and burning sensation in patients after total knee replacement with risk factors such as intraarticular steroid injection, intravenous drug abuse, immunosuppressive therapy, malignant hematologic tumor, etc. Positive culture of candida should never be considered as contaminated study, and be treated immediately. We report a case of candida infection after total knee arthroplasty, which was treated with staged reimplantation.
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