Demacre', a new topical steroid cream containing 0.025% beclomethasone dipropionate, was used in several kinds of dermatoses. Total 35 patients including ll cases of contact dermatitis, 5 of atopic dermatitis, 3 of hand eczema, 3 of seborrheic dermatitis, 2 of neurodermatitis, 2 of nummular eczema, 2 of autosensitization dermatitis, 1 of chronic eczema, 3 of psoriasis, 1 of insect bite, 1 of miliaria rubra, and 1 of intertrigo were treated by Demacre'. Among these patients, we observed excellent effects in 4 patients (11%), good effects in 22 patients (63%), and fair effects in 3 patients (9%). Namely, among these 35 patients, 26 patients (74%) revealed excellent to good therapeutic effects on their skin conditions with Demacre'. No untoward side effects were noted in all subjects treated with Demacre.
Beclomethasone ; Dermatitis ; Dermatitis, Atopic ; Dermatitis, Contact ; Dermatitis, Seborrheic ; Eczema ; Hand ; Humans ; Insect Bites and Stings ; Intertrigo ; Miliaria ; Neurodermatitis ; Psoriasis ; Skin ; Skin Diseases*

The crystalline surface layer protein (SLP) and a 28-32 kDa antigen of Rickettsia typhi were known as strong immunogens. We previously reported a cloning and sequence analysis of the SLP gene of R. typhi (slpT) and showed that the open reading frame of this gene encodes both the SLP and a 32-kDa protein. Our study also showed that a 48-kDa protein reacted strongly with polyclonal antiserum of a patient with murine typhus. In this study, we produced three recombinant proteins (SLP, 32-kDa, and 48-kDa protein) in E. coli as fusion proteins with maltose binding proteins. The reactivity of these proteins with patients' sera was investigated.
Clone Cells* ; Cloning, Organism* ; Crystallins ; Humans ; Maltose-Binding Proteins ; Open Reading Frames ; Recombinant Proteins ; Rickettsia typhi* ; Rickettsia* ; Sequence Analysis ; Typhus, Endemic Flea-Borne

Primary ovarian choriocarcinoma is an extremely rare germ cell neoplasm, and the prognosis is poor. Especially, the diagnosis of primary ovarian nongestational chori-ocarcinoma can be reliably established in a girl or innocent virgin. We report a case of primary ovarian, nongestational, pure choriocarcinoma in a 16-year-old woman. She died within 1 year after diagnosis in spite of the treatment with surgery and combin-ation chemotherapy.
Adolescent ; Choriocarcinoma ; Choriocarcinoma, Non-gestational* ; Diagnosis ; Drug Therapy ; Female ; Germ Cells ; Humans ; Pregnancy ; Prognosis

Three cases of hydatidiform mole with a coexisting fetus are described. In two cases, flow cytometric analysis of nuclear DNA content from paraffin-embedded, molar tissues and normal-appearing placental tissues showed diploid pattern. One case had karyotypes of 46, XX both in fetal skin fibroblasts and in molar tissues. Microscopically, the villi showed diffuse hydropic swelling with circumferential trophoblastic proliferations and consistent with the diagnosis of complete mole. Two patient had persistent gestational trophoblastic neoplasia on the follow-up. Therefore, in cases of hydatidiform mole with a coexisting fetus, dizygotic twin pregnancies composed of a normal pregnancy from one ovum and a complete mole pregnancy from the other ovum must be considered and the patients should be followed with serum beta-hCG measurements.
Pregnancy ; Female ; Humans

The organization of the ribosomal genes is unique in Borrelia burgdorferi in that the rrl (23S) and rrf (SS) genes are duplicated in tandem. Twelve Korean Borrelia isolates were classified by the method of rRNA gene restriction fragment length polymorphism (RFLP) and Southern hybridization. One of the isolates, KW-3, as well as the representative of ribotype group IV Ip89 appeared to have evolved within B. garinii. The size of the restriction bands of the 11 isolates showed different patterns from the USA and European isolates. The result by RFLP of rrf-rrl intergenic spacer region amplified by PCR showed a good correlation with that of Southern hybridization of rRNA gene. Therefore, the eleven Korean isolates could be classified as members of a new Borrelia group.
Borrelia burgdorferi Group* ; Borrelia burgdorferi* ; Borrelia* ; Classification* ; Genes, rRNA ; Korea* ; Polymerase Chain Reaction ; Polymorphism, Restriction Fragment Length* ; Ribotyping

Effectiveness of flubendazole, a newly introduced as an anthelmintic in Korea, was evaluated in 28 ascariasis, 28 whipworm infections and 17 pinworm infections in primary school children. All patients were orally given by flubendazole of 500 mg once. Stools for roundworm and whipworm and anal swabs for pinworm infections were examined both before and 25 days after treatment. After flubendazole treatment, all ascariasis and pinworm infected cases were cured. On the other hand, in whipworm infections, the cure rate was 82.1 percent (23 cured of 28 infected), and the egg reduction rate was 67.1 percent, respectively. Headache (one case), dizziness (2 cases) and abdominal pain (3 cases) were noticed as untoward effects, but they were mild and disappeared within 24 hours. These results demonstrate the excellent effectiveness of flubendazole in treating these helminth infections.
parasitology-helminth-nematoda ; Ascaris lumbricoides ; Trichocephalus trichiurus ; Enterobius vermicularis ; chemotherapy ; flubendazole

No abstract available.
Cauda Equina* ; Ependymoma*

No abstract available.
Animals ; Chick Embryo* ; Nicotine*

lmpedance audiometry requires physical modifications during the test, which might influence retest data. Therefore, in Order to interprete retest data meaningfully, the range of variation should be identified in each measure of impedence audiometry. The present study obtained data on the retest variation of peak pressure, acoustic reflex threshold, static compliance and earcanal volume in impedance audiometry. ln addition, the authors wanted to know whether or not impedance data would assist otolaryngologists in the detection of conductive hearing impairment. The variation of the retest data was not clinically nor statistically significant in the measurement except for those of ear canal volume. The data on ear canal volume also suggested that the ear canal increases in size during the teenage period and that male ear canals are larger than those of females in ears over 20 years of age. The impedance data assisted the otolaryngologist in the detection of conductive hearing impairment
Acoustic Impedance Tests ; Adolescent ; Adult ; Age Factors ; Aged ; Auditory Threshold/*physiology ; Child ; Child, Preschool ; Comparative Study ; Diagnostic Errors ; Hearing Loss/*diagnosis ; Hearing Loss, Conductive/*diagnosis/physiopathology ; Human ; Middle Age ; *Reflex, Acoustic ; Sex Factors ; Support, Non-U.S. Gov't ; Tympanic Membrane/*physiopathology

No abstract available.
Embryonic Structures* ; Humans* ; Upper Extremity*