No abstract available.
Myofibromatosis* ; Skull*

The clinical data of one case of infantile myofibromatosis of left mandibular angle were analyzed, and the clinicopathological characteristics, imaging diagnosis, treatment and prognosis of infantile myofibromatosis were discussed.
Humans ; Myofibromatosis ; congenital

Infantile myofibromatosis is a rare neoplasm which occurs primarily in early infancy and arise in the various sites. A 4-year-old boy, who presented with painless soft scalp mass in the left temporoparietal region was diagnosed to have myofibromatosis and this case is presented with some literature reviews.
Child, Preschool ; Humans ; Male ; Myofibroblasts ; Myofibromatosis* ; Scalp

Infantile myofibromatosis is a rare specific fibrous proliferations of infancy and childhood, but its clinical and histopathological natures are well described. In Korea, only two cases have been reported. We present an additional case of infantile myofibromatosis that developed on the left proximal palm of tow-month-old male infant since birth. The tumor was brownish to red in color, 2.5x 4.0cm in size and firmly palpated. The tumor was not only localized to the skin, but also involved the underlying 4th and 5th metacarpal bone so that caused hypoplasia of those bones.
Humans ; Infant* ; Korea ; Male* ; Myofibromatosis* ; Parturition ; Skin

Solitary myofibroma is a recently described, uncommon neoplasm of superficial soft tissue and presenting as an asymptomatic nodule of the skin, which mainly occurs in adults. It was thought to be the adult counterpart of infantile myofibromatosis. Although it has histopathological similarity to infantile myofibromatosis, it shows a discrete clinicopathological entity compared with infantile form on the basis of its much later onset, superficial location, invariable solitary occurrence and uniformly benign behavior. A 41-year-old female presented a skin lesion on the posterior neck for 1 year, which was a solitary, painless nodule. The excised tumor was diagnosed as myofibroma by light microscopy and immunohistochemistry.
Adult* ; Female ; Humans ; Immunohistochemistry ; Microscopy ; Myofibroma* ; Myofibromatosis ; Neck ; Skin

Infantile myofibromatosis is the most common of the juvenile fibromatoses and an unusual mesenchymal disorder characterized by the proliferation of tumors in the skin, muscle, bone and viscera. There are two forms of the disease: solitary and multicentric. A benign course with spontaneous regression is seen in most patients, but poor prognosis can be associated with the multicentric form, in which visceral organs may be involved. It usually presents in early childhood. We report a case of infantile myofibromatosis arising in the left sole of a female new born. Physical examination showed a firm, red colored 2x4cm sized tumor. Histological examination revealed a spindle cell tumor in the dermis with fascicles of plump spindle cells with a whorled arrangement.
Dermis ; Female ; Fibroma ; Humans ; Myofibromatosis* ; Physical Examination ; Prognosis ; Skin ; Viscera

Solitary myofibroma is an uncommon myofibroblastic neoplasm, presenting as an asymptomatic nodule of the skin, which mainly occurrs in adults. It was thought to be the adult counterpart of infantile myofibromatosis. Although it has histopathological similarity to infantile myofibromatosis, it shows a discrete clinicopathological entity compared with infantile form on the basis of its much later onset, superficial location, invariable solitary occurrence and uniformly benign behavior. A-45-year-old woman had a skin lesion on the right upper eyelid for 2 years, which was a solitary, painless nodule with eyelid retraction. The excised tumor was diagnosed as myofibroma by light microscopy and immunohistochemistry.
Adult* ; Eyelids* ; Female ; Humans ; Immunohistochemistry ; Microscopy ; Myofibroblasts ; Myofibroma* ; Myofibromatosis ; Skin

Infantile myofibromatosis is a rare benign tumor of childhood characterized by a myofibroblastic tumor in the skin, subcutaneous tissues, bones, and, occasionally, the viscera. The tumor may be solitary or multicentric. A solitary skeletal lesion most commonly occurs in the craniofacial region. We report a case of solitary infantile myofibromatosis of the skull, confirmed by excisional biopsy.
Biopsy ; Myofibroblasts ; Myofibromatosis* ; Skin ; Skull* ; Subcutaneous Tissue ; Viscera

The concept of perivascular myomas was recently proposed to designate perivascular myoid tumors arising from pleuripotent perivascular cells like smooth muscle cell cells, pericytes and glomus cell. They represent a histological continuum between three categories; myofibromatosis, glomangiopericytoma and myopericytoma. Myopericytoma is a rare, soft tissue tumor that primarily occurs in the skin and the subcutaneous and soft tissues of the extremities, but very few cases have been reported in other locations, which occurred in our present case. We herein report on a rare case of myopericytoma that developed on an unusual location, that is, the ear. The patient was a 35-year-old man who had a painless, slowly-growing red nodule on the upper auricle of the right ear for 5 years. The nodule was revealed to be a well-circumscribed mass composed of round to oval cells that strongly expressed smooth muscle actin. These cells were arranged in the concentrically multilayered pattern and they were surrounded by small to medium-sized vessels.
Actins ; Adult ; Ear ; Extremities ; Humans ; Muscle, Smooth ; Myocytes, Smooth Muscle ; Myofibromatosis ; Myoma ; Pericytes ; Skin

Infantile myofibromatosis is one of the most common fibrous proliferation of infancy, characterized by the development of non-tender, firm, discrete, flesh-colored to purple nodules in skin, muscle, bone, and subcutaneous tissues. Three distinct subtypes are recognized-solitary, multicentric and generalized subtype. In solitary and multicentric subtypes, the prognosis is excellent with expected spontaneous regression of nodules in 1 to 2 years. But the prognosis of generalized subtype is poor with 75% of patients dying within the first few months of life secondary to cardiopulmonary or gastrointestinal complications. We report a case of multicentric infantile myofibromatosis in a 4-year-old boy presenting with multiple, asymptomatic, fixed and protruding masses on the posterior occiput, shoulders, upper and lower back and right lateral chest wall. Over the subsequent 20 monthes, the child developed limitation of motion of back and shoulder with the repeated formation and disappearance of myofibromatosis of the skin and musculature, but without visceral involvement.
Child ; Child, Preschool ; Humans ; Male ; Myofibromatosis* ; Prognosis ; Shoulder ; Skin ; Subcutaneous Tissue ; Thoracic Wall