Apexcardiograms were evaluated in 24 normal adults (14 males and 10 females) aged 23 to 56 (mean 39) years and 42 patients with ischemic heart disease (29 males and 13 females) aged 40 to 81 (mean 57) years. The ratio of the duration of slow and rapid filling periods (SFP/RFP) and the height of the a wave in realtion to the total apexcardiographic deflection (a/H) were measured in each case and the results obtained from the IHD group were compared with data from the control group. The results obtained were as follows. 1. The was significant difference (p<0.001) between mean SFP/RFP ratio in control group (2.1+/-0.6) and in IHD group (3.4+/-1.5). Setting the upper SEP/RFP ratio at 2.7(mean+1 S.D.), 57.15 of IHD group and 20.8% of control group were above, and at 3.3(mean+2 S.D.), 40.5% of IHD group and none of control group were above this value. 2. There was no difference between the mean a/H ratio in control group (0.08+/-0.07) and in IHD group (0.09+/-0.11). The a/H ratio exceeding 0.15 (15%) was noted in 11.9% of IHD group. 3. The significance of SFP/RFP ratio in the apexcardiogram in the diagnosis of IHD was discussed. The SFP/RFP ratio is a more useful noninvasive adjunctive measurement for detecting IHD than a/H ratio.
Adult ; Diagnosis ; Humans ; Male ; Myocardial Ischemia*

Coronary Vasospasm ; diagnosis ; Female ; Humans ; Myocardial Ischemia ; diagnosis

Author analysed the postexercise electrocardiogram of 139 cases of normal group and 106 cases of cardiovascular disease according to Rhee's criteria, Master's criteria and Lepeschkin's criteria. following results were obtained: 1. 8.7% of normal group was revealed positive by Rhee's criteria of analysis of double Masters'2 step excrcise test, 9.3% by Master's criteria and 27.3% by Lepeschkin's criteria, were as 35.8% of cardiovascular cases was revealed positive by Rhee's criteria, 38.6% by Master's criteria, and 43.3% by Lepeschkin's criteria. 2. Almost the same positive ratio was revealed both when by UP segment of Master and when by O point of Lepeschkin were considered to be the baseline. 3. Determination of QT ratio and the QX/QT fraction had no diagnostic value of ischemic heart disease. 4. No significant relationship was found between abnormal response of exercise electrocardiogram and coronary risk factors. 5. After exercise test, T wave changes were found in few cases, where as U wave changes were found in many cases, but both changes had no diagnostic value of ischemic heart disease.
Cardiovascular Diseases ; Diagnosis* ; Electrocardiography* ; Exercise Test ; Myocardial Ischemia* ; Risk Factors

A new ST segment analysis scheme is developed for helping the doctors to browse the electrocardiogram (ECG) signals rapidly and then give a correct diagnosis. The preprocessing consists of baseline wander attenuation using median filter, high frequency noise rejection using order statistic filter, and then QRS complexes detection using wavelet analysis. In this paper, after the beginnings and the ends of the ST segments are mutually chosen by doctor, we compute the total deviations between ST segments and the modified baselines using mean value, and then plot the whole trend of the deviations. Doctors can browse the original ECG signals handily by our browsing system, and then give a diagnosis colligating other clinic features of the patient.
Electrocardiography, Ambulatory ; Humans ; Myocardial Ischemia ; diagnosis ; Signal Processing, Computer-Assisted

Atrial fibrillation is association a wide range of genetic, metabolic, and environmental causes. The number of patients with atrial fibrillation is increasing exponentially, predominantly due to aging and a variety of heart conditions such as ischemic heart disease and heart failure. Owing to a range of unmet clinical and social needs, atrial fibrillation has become a significant target for research studies. Thus far, research has revealed several important mechanisms related to the pathophysiology, diagnostic, and optimal treatment of atrial fibrillation. In this review, we aim to summarize the current status of research on atrial fibrillation and relate such progress to the European Atrial Fibrillation Guidelines (2016).
Aging ; Atrial Fibrillation* ; Diagnosis* ; Heart ; Heart Failure ; Humans ; Myocardial Ischemia

BACKGROUND: Diagnosis of myocardial ischemia in patients with symptoms suggesting acute coronary syndrome (ACS) is often difficult because of absence of well-defined markers to identify patients with myocardial ischemia. Recently, ischemia modified albumin (IMA) has been used as a sensitive and early marker of myocardial ischemia. We studied the clinical usefulness of IMA for detection of ACS with traditional cardiac markers such as CK-MB and cTnI. METHODS: We assessed 87 patients suspected of having ACS. This study evaluated IMA in conjunction with CK-MB and cTnI. All patients were reviewed by a cardiologist and classified into ACS (n=27), cerebrovascular disease (CVD) (n=11), and non-ACS (n=49) groups. Statistical analysis was performed with receiver operating characteristics (ROC) curve analysis and ANOVA with a multiple comparison test. RESULTS: ROC curves showed that IMA was more sensitive but less specific than cTnI and CK-MB, and that the optimal cutoff value of IMA was 110 U/mL for the detection of ACS. Particularly, when tested within 4 hours of the onset of symptoms, IMA detected 100% of the patients with ACS, including even those with normal electrocardiogram (ECG) and/or cTnI; however, 50% of the patients with positive IMA results (> or = cutoff value) had other conditions such as CVD including mainly ischemic stroke, cancer, trauma, and fat embolism, etc. On the other hand, most of the patients with negative IMA results were not ACS. CONCLUSIONS: IMA is a useful early marker for the identification of ACS, especially in patients with myocardial ischemia before or without MI with normal ECG and/or cTnI. A positive result of IMA is not necessarily to indicate where the ischemia has occurred; however, a negative IMA result can rule out ACS in the early phase of symptom onset.
Acute Coronary Syndrome* ; Diagnosis ; Electrocardiography ; Embolism, Fat ; Hand ; Humans ; Ischemia* ; Myocardial Ischemia ; ROC Curve ; Stroke

The vectorcardiography was performed on 34 cases with PRWP of precordial leads. We have studied the vectorcardiographic finding for the differential diagnosis of disease entities were obtrained; 1) Poor R-Wave progression of precordial leads has simply considered as suggestion of anterior myocardial infarction, ischemic heart disease, chronic lung disease and normal variant. 2) The sensitivity and specificity of myocardial infarction criteria were 85.8% and 63.0% respectively in left sagittal plane and 85.8% and 66.7% respectively in horizontal plane. 3) The seneitively and specificity of more than 90 QRS-T vector angle in left sagittal plane were 100.0% and 62.5% respectively in ischemic heart disease and myocardial infarction. 4) The sensitively and specificity of chronic lung disease criteria were 85.7% and 51.9% respectively. 5) Vectorcardiographic study was considered as effective differentiating method for patients with PRWP in EKG.
Diagnosis, Differential* ; Electrocardiography* ; Humans ; Lung Diseases ; Myocardial Infarction ; Myocardial Ischemia ; Sensitivity and Specificity ; Vectorcardiography*

Recently, MRI has achieved many technical advances in the spatial resolution, temporal resolution, signaltonoise ratio, and postprocessing software. As a result, cardiac MRI has made a sudden rise from old obscurity in the diagnosis of coronary artery disease. Cardiac MRI may be a onestopshop solution for the assessment of systolic dysfunction, perfusion impairment and myocardial viability, and for the imaging of stenosed artery. The evaluation of myocardial ischemia and viability are very important in the decision of therapeutic strategy and the anticipation of the prognosis of the patients with ischemic heart disease. At one session of examination, MRI can provide combined information on myocardial contractile function and myocardial perfusion, and unique information on the transmural extent of delayed hyper-enhancement. Delayed hyperenhancement on contrastenhanced MRI is highly reproducible irrespective of the scanning procedure and the operator, which is used for the interpretation of myocardial viability in the patients with myocardial infarction. Cardiac MRI is a very accurate and costeffective modality for the evaluation of ischemic heart disease.
Arteries ; Coronary Artery Disease ; Diagnosis* ; Humans ; Magnetic Resonance Imaging* ; Myocardial Infarction ; Myocardial Ischemia* ; Perfusion ; Prognosis

myocardial infarction (AMI) and the difference between regions has not been reported in Korea since 2010. Thus, we aimed to inspect recent trends and regional differences in the incidence of AMI and case-fatality between 2007 and 2016.METHODS: Data from the medical utilization cohort from 2002 to 2016 were analyzed. New incidence of AMI was identified by checking the diagnosis code, duration of admission, type of test, treatment, and medication. Age-standardized incidence rate by gender, age group, and resident region was calculated from 2007 to 2016. Cumulative case-fatality rate was calculated until 3 years.RESULTS: Age-standardized incidence of hospitalized AMI decreased from 53.6 cases per 100,000 person-years in 2007 to 38.9 cases in 2011. Thereafter, the incidence gradually increased to 43.2 cases in 2016. The trend by gender and age groups was also similar to the total trend. The regional age-standardized incidence was the highest in Daegu (50.3 cases per 100,000 person-years) and the lowest in Sejong (30.2 cases), which were similar to the ischemic heart disease mortality in these regions. The 7-, 30-, and 90-days and 1- and 3-years average case-fatality over 10 years were 3.2%, 6.9%, 9.9%, 14.7%, and 22.4%, respectively.CONCLUSION: Although case-fatality continuously decreased from 2007 to 2016, hospitalized AMI incidence decreased from 2007 to 2011 and gradually increased from 2011 to 2016, with marked disparity between regions. Effective preventive strategies to decrease AMI incidence are required to decrease cardiovascular disease mortality in Korea.]]>
Cardiovascular Diseases ; Cohort Studies ; Daegu ; Diagnosis ; Humans ; Incidence ; Korea ; Mortality ; Myocardial Infarction ; Myocardial Ischemia

Aged ; Biomarkers ; blood ; Cobalt ; Female ; Humans ; Male ; Middle Aged ; Myocardial Infarction ; diagnosis ; Myocardial Ischemia ; diagnosis ; Serum Albumin ; metabolism ; Spectrophotometry