BACKGROUND: Clinical and experimental studies have suggested that brain death may cause hemodynamic, electrocardiographic, functional or histopathologic changes of the heart. METHODS: Brain death was induced by increasing intracranial pressure(ICP) abruptly by intermittent bolus injection of saline(model ) or gradually by continuous infusion of saline(model ) to the epidural catheter in 5 mongrel dogs, respectively. Hemodynamic and biochemical changes during the process of brain death and histopathologic changes of the myocardium were analyzed and compared in two brain death models, and the association of apoptosis was also evaluated. RESULTS: 1) Two predominant subsets of acute contraction band lesion were produced in both brain death models : paradiscal and holocystic contraction band lesions. Both contraction band lesions were more prevalent in brain death model . 2) The frequency of both contraction band lesions was lowest in the epicardial layer and highest in the endocardial layer in both models, but no correlation was observed between the degree of contraction band lesions and ICP, LV maximum +dp/dt or catecholamine levels. There was no statistical difference between any of the LV circumferential blocks and either type of contraction band lesion, and transaxial distribution was not also different in both models. 3) There was no remarkable histopathologic changes in the analysis of major epicardial coronary arteries. Apoptotic cells were suggested in the scattered myocytes in the light microscopy and apoptosis was detected by in situ nick end labeling method. Electron microscopy revealed a condensation of nuclear chromatin and convolution of nuclear membrane in those myocytes. CONCLUSIONS: Myocardial changes due to brain were observed frequently, and few apoptotic cells were found in the brain death heart. Studies on the treatment strategy to minimize damages of myocardial structure and function caused by brain death should be followed in the near future.
Animals ; Apoptosis ; Brain Death* ; Brain* ; Catheters ; Chromatin ; Coronary Vessels ; Dogs ; Electrocardiography ; Heart ; Hemodynamics ; In Situ Nick-End Labeling ; Microscopy ; Microscopy, Electron ; Muscle Cells ; Myocardium* ; Nuclear Envelope

PURPOSE: The purpose of this study was to analyse the level of sexual function among breast cancer survivors as compared with that among healthy women. METHOD: A total of 208 women participated in this study: 103 breast cancer survivors attending self-help group and 105 community-residing healthy women in G city. A self-reported questionnaire with the Female Sexual Function Index (FSFI) was used to obtain data. Data were analyzed using the SPSS Win 14.0 K+ for descriptive statistics, t-test, and two-way ANOVA. RESULTS: The sexual function score of breast cancer survivors was significantly lower than that of healthy women, respectively 14.9+/-9.9 and 20.6+/-11.1 (p<0.001). The sexual function of recurrent breast cancer survivors was significantly lower than that of women without recurrence. However, there were no significant differences in the sexual function score according to the cancer stage, period since diagnosis, and types of cancer treatment modality. CONCLUSION: The findings indicate the importance of sex-related counseling and educational programs to improve the quality of life of breast cancer survivors.
Breast ; Breast Neoplasms ; Counseling ; Female ; Humans ; Quality of Life ; Surveys and Questionnaires ; Recurrence ; Self-Help Groups ; Survivors

PURPOSE: The purpose of this study was to identify the effect of head nurse's emotional leadership on nurse's job satisfaction & organizational commitment. METHODS: The subjects of this study were 385 nurses from four general hospitals and one university hospital. SPSS WIN 14.0 was used for data analysis. RESULTS: Stepwise multiple regression analyses were used to examine the influences of research variables. The variable which predict nurse's job satisfaction were head nurse's emotional leadership (F=76.027, p<.01, adjusted R square=.166). The variables which predict organizational commitment were emotional leadership (F=27.839, p<.01, adjusted R square=.066), marital status (F=20.928, p<.01 adjusted R square=.03), respectively. CONCLUSIONS: As a result of this study, head nurse's emotional leadership was defined as a important influential on both job satisfaction and organizational commitment of nurses. Therefore, it is needed to develop education programs for activating head nurse's emotional leadership.
Head ; Hospitals, General ; Job Satisfaction ; Leadership ; Marital Status ; Statistics as Topic

PURPOSE: This study provides useful basic information about caring for elderly women. It also promotes understanding by confirming what can vitalize the women and improve quality of life in elderly women as they continue to become important in the society which is moving towards being an "aged society". METHOD: Grounded theory a qualitative research method, was use to develop new thesis regarding life's vitality in elderly women. Thirteen women participated in the research. They were women without any problems in perception or communication and who agreed to participate in the research. RESULT: The results, using analysis process of Strauss and Corbin (1990), showed that life's vitality in elderly women is to bring well-being through vitalization against weakness. CONCLUSION: Based on such these results, this study will be helpful to nursing mediation and policy development which will improve the quality of life of elderly women through better understanding and promotion of life's vitality.
Aged* ; Female ; Humans ; Negotiating ; Nursing ; Policy Making ; Qualitative Research ; Quality of Life

The purpose of this study was to examine the effects of bisphosphonate and indomethacin, blockers of bone resorption with different mechanisms, on alveolar bone remodeling. Male rats were divided into control, bisphosphonate and indomethacin groups, and then each group was divided into an experimental side and a control side according to the force application. Bisphosphonate(6.3/kg, 2.52x10(-2)mol/L) and indomethacin (9mg/kg, 2.52x10(-2)mol/L) were injected 6 hours and 1 hour before or 24 hours after the force application. The rats were killed 72 hours after the force application and histologic examination was performed. The values of serum acid phosphatase and lactate dehydrogenase were also measured in the control and experimental groups treated with bisphosphonate or indomethacin 1 hour before the force application. In the experimental side, the least number of osteoclasts was noted in the groups treated 1 hour before the force application with indomethacin or bisphosphonate, while there were no differences between the control and the groups treated with drugs 6 hours before or 24 hours after the force application. In the control side, the number of osteoclasts was not inecreased with no differences among the groups. Histologic examination revealed a severe alveolar bone resorption in the control group and the groups treated with indomethacin 6 hours before or 24 hours after the force application. Indomethacin treatment 1 hour before the force application and bisphosphonate treatment at any time significantly attenuated the bone resorption. Electron microscopically, ruffled border and clear zone of osteoclasts were observed in the control and indomethacin groups, while some osteoclasts were detached from the bone surface and exhibited dull cellular projections in the bisphosphonate groups. The bisphosphonate and indomethacin groups showed lower values of acid phosphatase and lactate dehydrogenase than the control group. The acid phosphatase value in the bisphosphonate group was lower than that in the indomethacin group, whereas there was no difference in the lactate dehydrogenase value between the groups. These results suggest that bisphosphonate reduces the activity of osteoclasts as well as the number of osteoclasts and that indomethacin reduces the number of osteoclasts without affecting the activity of osteoclasts. Bisphosphonate has a larger inhibitory effect on bone resorption and thus less limitation in the application time than indomethacin.
Acid Phosphatase ; Animals ; Bone Remodeling* ; Bone Resorption ; Humans ; Indomethacin* ; L-Lactate Dehydrogenase ; Male ; Osteoclasts ; Rats* ; Tooth Movement

The causes of the missing teeth are classified as congenital missing, trauma and extraction due to dental caries, variable problems are occured clinically by the missing teeth. The missing of the upper incisors especially would assume a serious aspect, and could be treated by three methods of orthodontic treatment, prosthodontic treatment and autotransplantation of the premolar teeth. The patient of this report had the skeletal class II malocclusion with the left upper central incisor missing, and have been treated with the fixed appliance after extraction of the right upper central incisor and both lower second premolars. The results were obtained as follows: 1. Treatment was done for 1 year 6 months. 2. Normal overbite and overjet were achieved. 3. Cuspal interdigitation was obtained normally. 4. Space problem was resolved with resin restoration of the upper lateral incisors. 5. The upper canines were used as the upper laterals after cuspal contouring. 6. Retention would be required with adequate retainers for a long time to prevent relapsing after treatment.
Autografts ; Bicuspid ; Dental Caries ; Humans ; Incisor* ; Malocclusion* ; Overbite ; Prosthodontics ; Tooth

Tooth movement would be impeded by frictional force arised between archwire and tube, bracket or elastics in the fixed orthodontic appliances, which could be changed variably by such several factors as the contact area, normal (perpendicular) force and the condition of contact surface. There were many literatures about frictional force in the orthodontic region, but different results were obtained from little controlled research so that was very difficult in clinical application. Therefore we have reviewed comprehensively previous literatures about frictional force and thus several results were obtained as follows: 1. For use species of the orthodontic wire, frictional force was influenced mainly by surface roughness of wire in the absence of binding, while that was influenced mainly by normal force in high binding angulation. 2. For the cross-section and diameter of the wire, the contact area influenced mainly on frictional force in the absence of binding, while wire stiffness influenced mainly on frictional force in high binding angulation. 3. The greater the bracket width, the greater frictional force, and frictional force of the plastic bracket was larger than that of the metal bracket. 4. For ligation type, frictional force of the stainless steel ligation was larger than that of the elastic ligation, and frictional force was directly proportional to ligation force. 5. Variable frictional force were occured from the saliva combined with such another factors as normal force and mode of surface oxide et al.
Friction* ; Ligation ; Orthodontic Appliances* ; Orthodontic Wires ; Plastics ; Saliva ; Stainless Steel ; Tooth Movement* ; Tooth*

Public attitudes and awareness toward epilepsy were surveyed in Kwang-ju area. A representative population of 587 persons aged over 18 years was selected in a systematic sampling procedure from the Kwang-ju telephone directory published in 1991. The social background of the respondents did not deviated significantly from that of the general population in this age range. The questionnaire consisted of 34 guestions designed to determine the respondent's social background, acquaintance with epileptic patients, awareness of epilepsy, and opinions and attitudes about the disorder. The result from this survey was as follows; 1) The prejudice and misunderstanding toward epilepsy in our society were much more serious than those in other societies reviewed in this study, which may be due to our own peculiar cultural background. 2) Although social discrimination against persons with epilepsy was due mainly to social stigma on epilepsy based on extra-ordinary misunderstanding of people, a very passive and pessimistic attitude of the patient himself may be contributed to it considerably. 3) Even if the epileptic seizure was well controlled with appropriate antiepileptic drugs, the social attitude toward occupational activity of persons with epilepsy was very negative. 4) The negative attitude toward epilepsy in our society was closely correlated to the level of education and age of respondents; the older or less educated they were, the more objections they had.
Anticonvulsants ; Surveys and Questionnaires ; Education ; Epilepsy* ; Gwangju* ; Humans ; Prejudice ; Social Discrimination ; Social Stigma ; Telephone

PURPOSE: This study was to compare quality of life, sexual function, and depression between a group with sexually active women and the other with sexually inactive women who undertaken mastectomy. METHODS: Participants were 106 breast cancer patients who had spouse and participated in self-help group in Gwangju, Korea. The questionnaires were consisted of Quality of Life Index-Cancer Version (Q.L.I.-C), self-rating depression scale, and Female Sexual Function Index (FSFI). Data were analyzed using the SPSS Win 14.0 K+ for descriptive statistics, t-test, ANCOVA, and MANOVA. RESULTS: There were no homogeneity at age, job, educational years between sexually active vs. inactive groups. In sexually active group, mean age was 46.1, having job 34.5%, bachelor's degree 38.2%, and pre-menopause 79.2%; for the inactive group 49.6, 10.4%, 12.5%, and 52.7% seperately. There were significant differences in quality of life, sexual function, and depression between two groups when four covariates were controlled. The quality of life and sexual function in sexually active group were significantly higher than inactive group(p<0.001). The depression in sexually active group was significantly lower than inactive group(p<0.001). CONCLUSION: This study indicates that nurses are needed to counsel and intervene psychosexual approach especially sexually inactive women with breast cancer during the recovery period.
Breast Neoplasms ; Depression ; Female ; Humans ; Korea ; Mastectomy ; Premenopause ; Quality of Life ; Surveys and Questionnaires ; Self-Help Groups ; Sexual Behavior ; Spouses

PURPOSE: To evaluate the merits of this technique and to provide a standard for comparison with futuretreatment alternatives. MATERIALS AND METHODS: We retrospectively reviewed the records of 52 patients withdirect CCF treated at the Yonsei Medical Center between 1983 and 1997 by transarterial or transvenous embolizationusing detachable balloon(s) and/or coils. RESULTS: Among the 52 cases, 51 were traumatic in origin, while onlyone was the result of a ruptured aneurysm. The three most common presentations were chemosis, bruit, andpulsatile proptosis. Forty-five patients were successfully treated with detachable balloon(s) and/or coils andinternal carotid blood flow was preserved in 35. When coils were used (1993-7), the ICA preservation rate washigher than when they were not used (1983-92). To confirm statistical significance, however, more studies areneeded. Four patients who initially presented with incomplete occlusion showed spontaneous occlusion on follow upangiography. In two patients, surgical ligation was performed because embolization failed and there was incompleteocclusion of the fistula. We experienced complications such as transient 3rd and 6th cranial nerve palsy,migration of deflated balloons and coils to the lung, and loss of vision. CONCLUSION: Transarterial andtransvenous embolization with detachable balloon(s) and/or coils provides a high rate of fistula obliteration withlow morbidity. In particular, the use of coils led to an increased rate of ICA preservation, thus and isconsidered as a good treatment modality for CCF obliteration.
Aneurysm, Ruptured ; Cranial Nerves ; Exophthalmos ; Fistula* ; Humans ; Ligation ; Lung ; Retrospective Studies