PURPOSE: The purpose of this study was to analyse the level of sexual function among breast cancer survivors as compared with that among healthy women. METHOD: A total of 208 women participated in this study: 103 breast cancer survivors attending self-help group and 105 community-residing healthy women in G city. A self-reported questionnaire with the Female Sexual Function Index (FSFI) was used to obtain data. Data were analyzed using the SPSS Win 14.0 K+ for descriptive statistics, t-test, and two-way ANOVA. RESULTS: The sexual function score of breast cancer survivors was significantly lower than that of healthy women, respectively 14.9+/-9.9 and 20.6+/-11.1 (p<0.001). The sexual function of recurrent breast cancer survivors was significantly lower than that of women without recurrence. However, there were no significant differences in the sexual function score according to the cancer stage, period since diagnosis, and types of cancer treatment modality. CONCLUSION: The findings indicate the importance of sex-related counseling and educational programs to improve the quality of life of breast cancer survivors.
Breast ; Breast Neoplasms ; Counseling ; Female ; Humans ; Quality of Life ; Surveys and Questionnaires ; Recurrence ; Self-Help Groups ; Survivors

PURPOSE: The purpose of this study was to identify relationships between quality of sleep, symptom cluster, depression, environmental disorder, and quality of life among hospitalized cancer patients. METHODS: The subjects were 114 patients who underwent chemotherapy for colon cancer, gastric cancer, gynecologic cancer and breast cancer. They were recruited from the cancer center of a university hospital. Data were collected from August 4th to 30th, 2011. The questionnaires included the Korean sleep scale A (quality of sleep), MDASI-K (symptom cluster), the environmental sleep disturbing scale, Zung's depression scale, and the Korean version of EORTC QLQ-C30. The collected data was analyzed by t-test, ANOVA, multiple regression analysis using the SPSS 19.0 program. RESULTS: Functional QOL was negatively associated with symptom QOL (r=-.798, p<.001). Symptom cluster, depression, & spouse (46.3%) were the most powerful predictors for functional QOL (46.3%) and symptom QOL (53.4%). CONCLUSION: It is evident that oncology nurses need to evaluate two dimensions of quality of life for cancer patients, for example, functional and symptom QOL. We recommend nurses develop specific protocols for relieving physical symptoms and alleviating depression, and furthermore test the effectiveness of them.
Breast Neoplasms ; Colonic Neoplasms ; Depression ; Humans ; Quality of Life ; Spouses ; Stomach Neoplasms ; Surveys and Questionnaires

PURPOSE: This study was conducted to examine the effects of a multicultural course on nursing students' multicultural acceptability and competency. METHODS: The research design for this study was a non-equivalent control group, non-synchronized pre- and post-test. The experimental group (n=28) took 13 weeks of the multicultural course, while the control group (n=28) received only regular classes over the same period. Pre- and post-tests were done to identify the effects of the program. The data were collected using self-administered questionnaires and analyzed using the PASW 18.0 program. RESULTS: All indices of multicultural acceptability and competency in the experimental group were significantly higher than that of control group after the program, except for two: universality (a measure of multicultural acceptability) and multicultural awareness (a measure of multicultural competency). CONCLUSION: These results suggest that the multicultural course was effective in elevating the level of multicultural acceptability and competency among nursing students.
Cultural Competency ; Humans ; Nursing* ; Research Design ; Students, Nursing*

PURPOSE: This study was to compare quality of life, sexual function, and depression between a group with sexually active women and the other with sexually inactive women who undertaken mastectomy. METHODS: Participants were 106 breast cancer patients who had spouse and participated in self-help group in Gwangju, Korea. The questionnaires were consisted of Quality of Life Index-Cancer Version (Q.L.I.-C), self-rating depression scale, and Female Sexual Function Index (FSFI). Data were analyzed using the SPSS Win 14.0 K+ for descriptive statistics, t-test, ANCOVA, and MANOVA. RESULTS: There were no homogeneity at age, job, educational years between sexually active vs. inactive groups. In sexually active group, mean age was 46.1, having job 34.5%, bachelor's degree 38.2%, and pre-menopause 79.2%; for the inactive group 49.6, 10.4%, 12.5%, and 52.7% seperately. There were significant differences in quality of life, sexual function, and depression between two groups when four covariates were controlled. The quality of life and sexual function in sexually active group were significantly higher than inactive group(p<0.001). The depression in sexually active group was significantly lower than inactive group(p<0.001). CONCLUSION: This study indicates that nurses are needed to counsel and intervene psychosexual approach especially sexually inactive women with breast cancer during the recovery period.
Breast Neoplasms ; Depression ; Female ; Humans ; Korea ; Mastectomy ; Premenopause ; Quality of Life ; Surveys and Questionnaires ; Self-Help Groups ; Sexual Behavior ; Spouses

PURPOSE: This study was conducted to evaluate clinical competency of nursing students and to examine the validity and reliability of the scale. METHODS: The Clinical Competency Scale was formed through modification of Lee's Clinical Competency Scale that was originally developed in 1990. The Clinical Competency Scale was applied to 203 nursing students. Construct validity, item convergent and discriminant validity, concurrent validity, and internal consistency reliability of the scale were evaluated. RESULTS: Exploratory factor analysis supported the construct validity with a five factor solution; that explained 63.6% of the total variance. Concurrent validity was demonstrated with the Nursing Competence Scale (r=.78, p < .001). Cronbach's α coefficient for the scale was .96. CONCLUSION: The results of this study suggest that the Clinical Competency Scale has relatively acceptable reliability and validity and can be used in clinical research to assess clinical competency for nursing students.
Clinical Competence ; Humans ; Mental Competency ; Nursing ; Psychometrics ; Reproducibility of Results ; Students, Nursing

We report distinctive diffusion-weighted magnetic resonance image (DWI) findings in a 65-year-old man with clinically diagnosed Creutzfeldt-Jakob disease (CJD). Four weeks before admission he developed general weakness and febrile sense which were followed by progressive dementia, ataxia, and choreo-athetoid movement of the right hand. T2-weighted magnetic resonance image (MRI) showed subtle high signal intensities only in the left basal ganglia, whereas DWI demonstrated marked hyperintensities in multiple regions including the left basal ganglia and left cerebral cortex. Five weeks after the onset of symptoms, he was noted to have myoclonus and characteristic electroencephalographic changes consisting of periodic triphasic sharp waves. In our patient, high signal changes on the DWI preceded myoclonus and typical EEG findings, a result suggesting that DWI may be useful in the early premortem diagnosis of CJD.
Aged ; Ataxia ; Basal Ganglia ; Cerebral Cortex ; Creutzfeldt-Jakob Syndrome* ; Dementia ; Diagnosis ; Electroencephalography ; Hand ; Humans ; Myoclonus

PURPOSE: The purposes of this study were to investigate the effect of Korean Red Ginseng(KRG) extract on the relaxation of the clitoral corpus cavernosal smooth muscle in rabbit. MATERIALS AND METHODS: Rabbit clitoral corpus cavernosal smooth muscle strips were mounted in organ chambers to measure isometric tension. The strips were contracted with phenylephrine(5 x 10(-6) M), and the responses to KRG extract(1~20 mg/ml), nitric oxide inhibitor(N omega-nitro-L-arginine methyl ester, L-NAME), vasoactive intestinal peptide(VIP) receptor antagonist, KCl were examined. The cGMP content of the strips was measured by radioimmunoassay after various dose of KRG extract. RESULTS: The KRG extract(1~20 mg/ml) relaxed the clitoral corpus cavernosal smooth muscle in a dose-dependent manner up to 95%. The relaxation effect of KRG extract was significantly inhibited by L-NAME(10(-4) M) in clitoral corpus cavernosal smooth muscle. The KRG extract also inhibited the contraction induced by depolarization with 10, 20, 40 mM of KCl. The KRG extract(1, 5 mg/ml) increased the accumulation of cGMP in clitoral corpus cavernosal smooth muscle. CONCLUSIONS: These data suggest that KRG extract has a relaxing effect on the clitoral corpus cavernosal smooth muscle in rabbit. These effects are in part mediated by the NO-cGMP pathway and a hyperpolarizing action.
Clitoris ; Female ; Muscle, Smooth ; Nitric Oxide ; Panax* ; Rabbits ; Radioimmunoassay ; Relaxation*

BACKGROUND: A randomized, multicenter, open-label, parallel group study was performed to compare the effects of remifentanil and morphine as analgesic drugs on the duration of weaning time from mechanical ventilation (MV). METHODS: A total of 96 patients with MV in 6 medical and surgical intensive care units were randomly assigned to either, remifentanil (0.1-0.2 mcg/kg/min, n = 49) or morphine (0.8-35 mg/hr, n = 47) from the weaning start. The weaning time was defined as the total ventilation time minus the sum of controlled mode duration. RESULTS: Compared with the morphine group, the remifentanil-based analgesic group showed a tendency of shorter weaning time (mean 143.9 hr, 89.7 hr, respectively: p = 0.069). Secondary outcomes such as total ventilation time, successful weaning rate at the 7th of MV day was similar in both groups. There was also no difference in the mortality rate at the 7th and 28th hospital day. Kaplan-Meyer curve for weaning was not different between the two groups. CONCLUSIONS: Remifentanil usage during the weaning phase tended to decrease weaning time compared with morphine usage.
Analgesics ; Humans ; Critical Care ; Morphine* ; Mortality ; Respiration, Artificial* ; Ventilation ; Ventilator Weaning ; Weaning*

No abstract available.
Morphine* ; Respiration, Artificial* ; Weaning*

PURPOSE: In this study the reliability and validity of the Korean version of the Cancer Stigma Scale (KCSS) was evaluated. METHODS: The KCSS was formed through translation and modification of Cataldo Lung Cancer Stigma Scale. The KCSS, Psychological Symptom Inventory (PSI), and European Organization for Research and Treatment of Cancer Quality of Life Questionnaire - Core 30 (EORTC QLQ-C30) were administered to 247 men and women diagnosed with one of the five major cancers. Construct validity, item convergent and discriminant validity, concurrent validity, known-group validity, and internal consistency reliability of the KCSS were evaluated. RESULTS: Exploratory factor analysis supported the construct validity with a six-factor solution; that explained 65.7% of the total variance. The six-factor model was validated by confirmatory factor analysis (Q (χ2/df)= 2.28, GFI=.84, AGFI=.81, NFI=.80, TLI=.86, RMR=.03, and RMSEA=.07). Concurrent validity was demonstrated with the QLQ-C30 (global: r=-.44; functional: r=-.19; symptom: r=.42). The KCSS had known-group validity. Cronbach's alpha coefficient for the 24 items was .89. CONCLUSION: The results of this study suggest that the 24-item KCSS has relatively acceptable reliability and validity and can be used in clinical research to assess cancer stigma and its impacts on health-related quality of life in Korean cancer patients.
Female ; Humans ; Lung Neoplasms ; Male ; Quality of Life ; Reproducibility of Results* ; Social Stigma