4.Some clinical and cytologic features of erythrocyte in peripheral blood and marrow of patients with myelodysplastic syndrome type persistent anemia
Journal of Vietnamese Medicine 2001;267(12):42-46
A total of 30 myelodysplastic syndromes (MDS) patients was analyzed to determine the clinical aspects and erythroid morphology in peripheral blood and bone marrow. The results are summarized as follows: 63.3% of patients was (50 years old. Male/Female ratio: 0.8. 46.7% were with lonely anemia and the rest were anemia combined with hemorrhages, infections, hepatosplenomegaly and lymphadenopathy. In peripheral blood: 63.4% of patients was with Hb<60g/l. 50% had normocrom - normocytic erythrocyte 96.7% of patients had dysmorphologic erythrocyte. In bone marrow: 46.6% were with hyperplasia of erythroid lineage, 33.6% were with hypoplasia of erythroid lineage, the rest (20%) were with normoplasia of erythroid lineage, 63.4% had dysmorphologic erythroblast, in which 36.7% was with ringed syderoblast
Myelodysplastic Syndromes
;
blood
;
diagnosis
;
cytology
;
Erythrocytes
;
anemia
10.Myelodysplastic Syndrome with Delayed Maturation of Reticulocytes: A Report of Three Cases.
Sung Eun YANG ; Joon Seok PARK ; Eul Zu SEO ; Hyun Sook CHI
Korean Journal of Clinical Pathology 1998;18(2):126-129
Anemia in myelodysplastic syndrome (MDS) is accompanied by reticulocytopenia in most patients. Reticulocytosis, when present, is generally less than appropriate to the degree of anemia and rarely exceeds 10%. In this report, three patients with MDS with persistent reticulocytosis are presented. In vitro reticulocyte survival studies have suggested that the reticulocytosis was caused by delay in maturation of the reticulocytes. Anemia with reticulocytosis, mimicking hemolytic disease, may be an unusual presentation of myelodysplastic syndrome, but, we emphasize that MDS should be included in the differential diagnosis of every patient presenting with anemia and high reticulocyte count. In vitro reticulotye survival study is easy to assess and valuable to diagnose this disease entity.
Anemia
;
Diagnosis, Differential
;
Humans
;
Myelodysplastic Syndromes*
;
Reticulocyte Count
;
Reticulocytes*
;
Reticulocytosis