Humans ; Myelodysplastic Syndromes ; diagnosis ; Prognosis

Humans ; Myelodysplastic Syndromes ; diagnosis ; therapy

Humans ; Myelodysplastic Syndromes ; diagnosis ; therapy

A total of 30 myelodysplastic syndromes (MDS) patients was analyzed to determine the clinical aspects and erythroid morphology in peripheral blood and bone marrow. The results are summarized as follows: 63.3% of patients was (50 years old. Male/Female ratio: 0.8. 46.7% were with lonely anemia and the rest were anemia combined with hemorrhages, infections, hepatosplenomegaly and lymphadenopathy. In peripheral blood: 63.4% of patients was with Hb<60g/l. 50% had normocrom - normocytic erythrocyte 96.7% of patients had dysmorphologic erythrocyte. In bone marrow: 46.6% were with hyperplasia of erythroid lineage, 33.6% were with hypoplasia of erythroid lineage, the rest (20%) were with normoplasia of erythroid lineage, 63.4% had dysmorphologic erythroblast, in which 36.7% was with ringed syderoblast
Myelodysplastic Syndromes ; blood ; diagnosis ; cytology ; Erythrocytes ; anemia

Humans ; Myelodysplastic Syndromes ; classification ; diagnosis ; Reference Standards

China ; Humans ; Myelodysplastic Syndromes ; diagnosis ; therapy

Child ; Humans ; Myelodysplastic Syndromes ; diagnosis ; Prognosis

Animals ; Humans ; Myelodysplastic Syndromes ; diagnosis ; genetics ; therapy

Anemia, Aplastic ; diagnosis ; Diagnosis, Differential ; Humans ; Myelodysplastic Syndromes ; diagnosis

Anemia in myelodysplastic syndrome (MDS) is accompanied by reticulocytopenia in most patients. Reticulocytosis, when present, is generally less than appropriate to the degree of anemia and rarely exceeds 10%. In this report, three patients with MDS with persistent reticulocytosis are presented. In vitro reticulocyte survival studies have suggested that the reticulocytosis was caused by delay in maturation of the reticulocytes. Anemia with reticulocytosis, mimicking hemolytic disease, may be an unusual presentation of myelodysplastic syndrome, but, we emphasize that MDS should be included in the differential diagnosis of every patient presenting with anemia and high reticulocyte count. In vitro reticulotye survival study is easy to assess and valuable to diagnose this disease entity.
Anemia ; Diagnosis, Differential ; Humans ; Myelodysplastic Syndromes* ; Reticulocyte Count ; Reticulocytes* ; Reticulocytosis