The therapeutic applications of Soft Contact Lenses including its optical use are most popular, devices in Ophthalmological field. The presoaked soft contact lenses (Bionite Lens) by 1% pilocarpine,10% phenylnephrine. 1% homatropine, and 1% atropine for 4 minutes are inserted into the albino rabbit and the size of pupil was measured using mm. caliper under the dim red light in the dark room. Hourly measurements were carried out and were stopped in each subject when the pupil size of both eyes had returned to normal. The pupil size of control group, which only the above drug were instilled into the conjunctival cuI de sac, was also measured as the same method. As conclusion using soft contact lens in the therapeutic purpose, it potentiate the effect of medication and prolong the time of drug effect compared with the control groups.
Atropine ; Contact Lenses, Hydrophilic* ; Miotics* ; Mydriatics* ; Pupil

PURPOSE: We tried to evaluate the reliablility of refractive measurement by hand-held autorefractor (HHAR). METHODS: Ninety patients (180 eyes) with simple refractive error were divided into three groups (30 patients each) according to their ages. Group I is under 6 years old; group II, from 7 to 15 years old; and group 3, over 16 years old. Under cycloplegics, three measuring methods of refraction using table top autorefractor (Model 599, Zeiss Humphrey, USA), hand-held autorefractor (Retinomax K-plus, Nikon, Japan) and skiascope (Heine beta 200, Germany) were performed and we compared each spherical and cylindrical value in 3 groups. RESULTS: There was no significant difference in both spherical and cylindrical value between HH-AR and skiascope in all groups (PI, sph=0.579, PI, cyl=0.708, PII, sph=0.801, PII , cyl=0.730, PIII , sph=0.816, PIII, cyl=0.754) . But there was significant difference in both spherical and cylindrical value between table top autorefractor and skiascope in group I (PI,sph=0.019, PI,cyl=0.030, PII,sph=0.405, PII,cyl=0.392, PIII,sph=0.876, PIII,cyl=0.747). CONCLUSIONS: We believe that hand-held autorefractor can be a useful instrument to measure refractive power without serious error, especially in patients who have difficulty with table top autorefractor.
Adolescent ; Child ; Humans ; Mydriatics ; Refractive Errors

Usual managements of flat anterior chamber following filtering surgery are deepening of anterior chamber using cycloplegics and mydriatics, and pressure patch technique compressing the fistula. But the pressure patch technique may worsen chamber depth problem because exact compression on the filtering area is difficult by pressure patching. Prolonged pressure patching may also cause deterioration of filtering function. The tampon with glaucoma shell provides enough resistance to excessive outflow, allows the anterior chamber to reform promptly, and can prevent choroidal separation. We treated the flat anterior chamber following trabeculectomy using glaucoma shell in 7 eyes. The anterior chamber in each eye was restored promptly within 2-4 days after the placement of glaucoma shell. Glaucoma shell is easy to handle, gives minimal discomfort to patient, and may need less time to restore flat anterior chamber than pressure patching.
Anterior Chamber* ; Choroid ; Filtering Surgery ; Fistula ; Glaucoma* ; Humans ; Mydriatics ; Trabeculectomy*

The hypotony with cyclodialysis after blunt trauma to the eye rarely happens and the cyclodialysis is diagnosed by finding the cleft in the anterior chamber anglel It is treated with cycloplegics conservatively or with surgery. In this study, the authors reviewed the hyphema, the onset of hypotony, the size of cyclodialysis cleft and transient scleral buckling that is one of the surgery in 7 eyes of 7 patients . The hyphema was seen in all cases after blunt trauma to the eyes and the duration between the trauma and the onset of hypotony was average 7.2 days. The traumatic cyclodialyses clefts were half an clock hour in 3 patients and 1 to 4 clock hours in 4 patients . Six patients had an initial conservative treatment, 3 patients required surgical treatment, scleral buckling, for 3 weeks for the full recovery of intraocular pressure.
Anterior Chamber ; Humans ; Hyphema ; Intraocular Pressure ; Mydriatics ; Scleral Buckling

We compared the differences of the intraocular pressure measured by the applanation and the Schiotz tonometer according to the ocular rigidity and its changes. We also did it by sex difference, age and the ocular rigidity range. The Korean 254 normal eyes, 12 aphakic eyes, 32 mydriatics treated eyes and 102 myopic eyes were examined. The intraocular perssure was measured by Goldmann applanation tonometer and Schiotz indentation tonometer using the 5.5 gram and 10.0 gram plunger load successively. The ocular rigidity was estimated from the Moses and Becker table. The results were as follows: 1. The mean ocular rigidity of the male and the female Korean was 0.0157 and 0.0195, respectively. There was no significant differences between the two tonometric values. 2. There was no significant ocular rigidity changes according to ages, and there was no statistically significant differences between the two tonometric values, 3. There was no statistically significant differences between the two tonometric values according to the ocular rigidity range. 4. The mean ocular rigidity of normal eyes, aphakic eyes. mydriatics treated eyes and myopic eyes was 0.0183 0.0166, 0.0164 and 0.0170, respectively, and there was no significant differences between the two tonometric values in each groups.
Female ; Humans ; Intraocular Pressure ; Male ; Manometry* ; Mydriatics ; Sex Characteristics

PURPOSE: To evaluate the changes of higher-order aberrations of the eye with the application of various mydriatics. METHODS: Higher-order aberrations were measured in 18 eyes of 11 subjects (ages 26 to 37 years; 9 males, 2 females) without any ocular diseases except refractive errors. Repeated measurements were conducted before and after instillation of 1 drop of three different mydriatics: 10% phenylephrine, a combination of 0.5% tropicamide and 0.5% phenylephrine (Mydrin(R)-P), and 1% cyclopentolate. The data from 6 mm pupil size were calculated and analyzed. RESULTS: Average root mean square of higher-order (HO-RMS) aberrations was 0.39 in undilated eyes. The averages HO-RMS after instillation of phenylephrine, Mydrin(R)-P, and cyclopentolate was 0.40, 0.41, and 0.42, respectively. There was no statistically significant difference among the four HO-RMS conditions. The spherical aberration of undilated or phenylephrine-instilled condition was different from that of Mydrin(R)-P or cyclopentolate condition (p<0.05). CONCLUSIONS: The application of mydriatics affected the higher-order aberrations of eyes. These findings should be considered when performing wavefront-guided refractive surgery.
Cyclopentolate ; Humans ; Male ; Mydriatics* ; Phenylephrine ; Pupil ; Refractive Errors ; Refractive Surgical Procedures ; Tropicamide

As the number of diabetic patient increases, it is important to manage diabetic retinopathy. Clinically sufficient pupillary dilatation should be obtained for fundoscopic examination and laser photocoagulation theraphy of diabetic patient but we experienced insufficient and delayed pupillary dilatation after instillation of mydriatics. In order to examine abnormality of pupillary dilatation and its relationship to the stage of diabetic retiniopathy, the course of pupillary diameter was measured with Haab's pupillometer after instillation of one drop of 1% Mydriacyl(R) and 2.5% Mydfrin(R) in 72 patients with diabetes mellitus (40-69 years old) and 11 normal controls (40-69 years old). The following results were obtained. After instillation of 1% Mydracy(R), the maximum pupillary diameter was smaller in diabetic retinopathy group than in controls. As the severity of diabetic retinopathy was increased, maximum pupillary diameter was decreased. After instillation of 2.5% Mydfrin(R), the delay of the average time to reach maximal mydriasis in diabetic group was larger than that in controls. This delay was proportional to the severity of diabetic retinopathy. Therefore it was considered that the abservation of the course of pupillary diameter after instillation of mydriatics would be useful for diagnosis of the severity of diabetic retinopathy.
Diabetes Mellitus ; Diabetic Retinopathy* ; Diagnosis ; Dilatation* ; Humans ; Light Coagulation ; Mydriasis ; Mydriatics*

PURPOSE: To evaluate the efficacy of 3 cycloplegic regimens in adults with myopia. METHODS: Refraction, accommodation amplitude, residual accommodation and biometric findings were assessed before and after instillation of regimen I (tropicamide 0.5% and phenylephrine 0.5%), regimen II (cyclopentolate 1.0%), and regimen III (combination of regimen I and II). RESULTS: In myopic adults aged 22 to 26 years, cycloplegic refraction revealed less myopia than manifested refraction. Although there was no difference in residual accommodation among the 3 regimens, regimen II and III were more effective in reducing myopia, accommodation, and axial length. The difference in cycloplegic refraction between regimen I and II was more prominent in patients who had larger amplitude of accommodation and residual accommodation with regimen I. CONCLUSIONS: Cycloplegic refraction should be used even in adult myopes. For patients with stronger accommodation and larger residual accommodation with tropicamide, cycloplegic refraction with cyclopentolate may be used to ensure relaxation.
Adult ; Aged ; Cyclopentolate ; Dietary Sucrose ; Humans ; Mydriatics ; Myopia ; Phenylephrine ; Refractive Errors ; Relaxation ; Tropicamide

The authors have experienced two cases of malignant glaucoma which were developed after a fistulizing procedure for subacute angle closure glaucoma. At first we tried to treat malignant glaucoma with conventional methods, such as mydriatics, diamox, hyperosmotic agents and posterior sclerotomy with air injection into the anterior chamber. But we failed to lower the intraocular pressure and reform the anterior chamber. Finally, combined trabeculectomy with lens extraction relieved the ocular pain and normalized intraocular pressure and obtained good visual acuity.
Acetazolamide ; Anterior Chamber ; Glaucoma* ; Glaucoma, Angle-Closure ; Intraocular Pressure ; Mydriatics ; Trabeculectomy* ; Visual Acuity

We studied the effect of MS-15, a new ophthalmic non steroidal antiinflammatory agent (Indomethacin), on reducing pupillary constriction during cataract surgery. Prior to surgery 0.5% of ibuprofen lysinate or a placebo was instilled 7 times and the surgeon's normal regimen of mydriatics and cycloplegics was used. MS(R) 15(0.5% ibuprofen lysinate) was far more effective than the placebo in maintaining dilated pupil during the cataract surgery. The change of the pupillary diameter from the conjunctival incision to after lens cortex aspiration averaged 0.42mm in MS-15 treatment group and 0.98 mm in placebo group. The difference between two groups was statistically significant(0.001 Cataract Extraction* ; Cataract* ; Constriction ; Double-Blind Method* ; Ibuprofen ; Mydriasis* ; Mydriatics ; Pupil