Acquired Immunodeficiency Syndrome ; microbiology ; Female ; Humans ; Mycoses ; diagnosis ; Young Adult

Adult ; Diagnostic Errors ; Female ; Humans ; Laryngitis ; diagnosis ; microbiology ; Male ; Middle Aged ; Mycoses ; diagnosis ; Pharyngitis ; diagnosis ; microbiology

Adult ; Granuloma, Respiratory Tract ; microbiology ; Humans ; Male ; Mycoses ; diagnosis ; therapy ; Pharyngeal Diseases ; diagnosis ; microbiology ; therapy

OBJECTIVE: The study was to evaluate the quality of life in patients with fungal rhino-sinusitis(FRS) and to investigate the relationship between different subjective tests.objective measures and that between subjective tests and objective measures. METHOD: Quantitative data of 18 preoperative recruits with FRS were collected by using sino-nasal outcome test-20 (SNOT-20) and then the SNOT-20 items were categorized into five domains, a visual analogue scale (VAS). Lund-Kennedy endoscopy staging system and the Lund-Mackay CT staging system. Correlation among these data was analyzed. RESULT: The six highest score items in SNOT-20 were Facial pain/pressure, Thick nasal discharge, Need to blow nose, Sneezing, Fatigue, and Frustrated/restless/irritable. The total SNOT-20 score was not correlated with the other objective or subjective tests(P > 0.05). However, there was significant correlation between SNOT-20 nasal symptom domain and Lund-Mackay T score( r = 0.605, P < 0.01), as well as between SNOT-20 sleep related symptom domain and VAS (r = 0.605, P = 0.008). Significant correlation was found between the Lund-Mackay CT staging and the VAS (r = 0.6150, P < 0.01), as well as between the Lund-Mackay CT staging and the Lund-Kennedy endoscopy staging (r = 0.5001 P < 0.05). There was no significant correlation between Lund Kennedy endoscopy staging and the patient-based questionnaires (P > 0.05). CONCLUSION The objective measures were correlated well with each other and CT staging had significant correlation with the SNOT-20 nasal symptom domain and VAS. There was also significant correlation between SNOT-20 sleep related symptom domain and VAS.
Female ; Humans ; Male ; Middle Aged ; Mycoses ; diagnosis ; Quality of Life ; Sinusitis ; diagnosis ; microbiology ; Surveys and Questionnaires

Humans ; Infant, Newborn ; Infant, Premature ; Infant, Premature, Diseases ; diagnosis ; microbiology ; prevention & control ; Mycoses ; diagnosis ; prevention & control

A 70 years old male patient complained a sense of swelling on right facial, mild pain, and the obstruction of right nasal, no complain of facial numbness and toothache. Physical examination showed the slight bulging on right facial with mild tenderness, purulent nasal secretions on the right middle nasal meatus, and no significant neoplasm. CT scan showed that soft density tissue in the right maxillary sinus,and the high density tissue in some period. Postoperative diagnosis: carcinoma of maxillary sinus with fungal sinusitis.
Aged ; Carcinoma ; complications ; diagnosis ; Humans ; Male ; Maxillary Sinus ; microbiology ; pathology ; Mycoses ; complications ; Nose Neoplasms ; complications ; diagnosis ; Sinusitis ; microbiology

Antifungal Agents ; therapeutic use ; Humans ; Male ; Mycoses ; diagnosis ; drug therapy ; Near Drowning ; microbiology ; Scedosporium ; pathogenicity

A young female complained repeated nasal discharge for over three months with discomfort of right cheek, and oral antibiotics had less effect. She has a history of "root canal therapy" five years before. Physical examination found purulent secretion in the right middle nasal meatus, and light tenderness in the right side of the maxillary sinus area. The CT scan of paranasal sinus shown possible fungal infection of right maxillary sinus. Finally the nasal endoscopic surgery confirmed the fungus ball of right maxillary sinus with foreign body (the root canal filling material).
Endoscopy ; Female ; Foreign Bodies ; diagnosis ; Humans ; Maxillary Sinus ; microbiology ; Maxillary Sinusitis ; microbiology ; Mycoses ; diagnosis ; Respiratory Tract Infections ; microbiology ; Tomography, X-Ray Computed

OBJECTIVE: To investigate the presentation and the management of allergic fungal rhinosinusitis (AFRS). METHOD: One case of AFRS was reported and the relevant literatures were reviewed. CT scan showed high-attenuation like "cloud and mist", Charcot-Leyden crystals and fungal hyphae were found in nasal smear. RESULT: The patient removed after a combined therapy of endoscopic sinus surgery, steroids and local antifungal drugs. CONCLUSION The diagnosis of AFRS depends on history, the characteristics of CT scanning, pathology, mycologic and immunologic test. The management of surgery, systemic immunotherapy, local antifungal drugs and longer follow up is very important.
Fungi ; isolation & purification ; pathogenicity ; Humans ; Male ; Mycoses ; diagnosis ; therapy ; Rhinitis, Allergic, Perennial ; diagnosis ; microbiology ; therapy ; Young Adult

OBJECTIVE: To analyze the clinical characteristics, diagnosis and treatment course and clinical effect of non-invasive fungal rhino-sinusitis, and to investigate the diagnostic and treating methods and factors affecting the clinical outcome. METHOD: A retrospective study was conducted on 111 patients who were diagnosed with noninvasive fungal rhino-sinusitis from 2005 to 2009 in our department. Clinical symptoms, endoscopic and CT examinations, surgical methods, surgical outcomes and the treatment of the recurrent cases were reviewed. RESULT: Eighty-six cases were reassured of the non-invasive fungal rhino-sinusitis by means of clinical symptoms, endoscopic and CT examinations. All the patients who underwent functional endoscopic sinus surgery showed satisfying clinical effect and no complications occurred. During the follow-up, recurrence was found in 12 cases 1 to 5 years postoperatively, and 7 were cured after medication and debridement under endoscope in outpatient department while the clinical outcome of the other 5 was unsatisfactory. CONCLUSION Non-invasive fungal rhino-sinusitis is distinctive in endoscopic and CT examination which is different from common chronic rhino-sinusitis, and endoscopic sinus surgery is an effective treatment for the disease. Radical debridement and successful drainage of the nasal sinus is the key factor affecting the effect of the treatment and clinical outcome.
Adolescent ; Adult ; Aged ; Female ; Fungi ; Humans ; Male ; Middle Aged ; Mycoses ; diagnosis ; Retrospective Studies ; Rhinitis ; classification ; diagnosis ; microbiology ; Sinusitis ; classification ; diagnosis ; microbiology ; Young Adult