1.Clarithromycin Susceptibility Testing of Mycobacterium avium Complex Using 2,3-Diphenyl-5-thienyl-(2)-tetrazolium Chloride Microplate Assay with Middlebrook 7H9 Broth.
Young Kil PARK ; Won Jung KOH ; Shin Ok KIM ; Sonya SHIN ; Bum Joon KIM ; Sang Nae CHO ; Sun Min LEE ; Chulhun L CHANG
Journal of Korean Medical Science 2009;24(3):511-512
A series of 119 Mycobacterium avium complex isolates were subjected to clarithromycin susceptibility testing using microplates containing 2,3-diphenyl-5-thienyl-(2)-tetrazolium chloride (STC). Among 119 isolates, 114 (95.8%) were susceptible to clarithromycin and 5 were resistant according to the new and the standard method. STC counts the low cost and reduces the number of procedures needed for susceptibility testing.
Clarithromycin/*pharmacology
;
Culture Media
;
Humans
;
Microbial Sensitivity Tests/*methods
;
Mycobacterium avium Complex/*drug effects/isolation & purification
;
Tetrazolium Salts/*chemistry
2.Clarithromycin Susceptibility Testing of Mycobacterium avium Complex Using 2,3-Diphenyl-5-thienyl-(2)-tetrazolium Chloride Microplate Assay with Middlebrook 7H9 Broth.
Young Kil PARK ; Won Jung KOH ; Shin Ok KIM ; Sonya SHIN ; Bum Joon KIM ; Sang Nae CHO ; Sun Min LEE ; Chulhun L CHANG
Journal of Korean Medical Science 2009;24(3):511-512
A series of 119 Mycobacterium avium complex isolates were subjected to clarithromycin susceptibility testing using microplates containing 2,3-diphenyl-5-thienyl-(2)-tetrazolium chloride (STC). Among 119 isolates, 114 (95.8%) were susceptible to clarithromycin and 5 were resistant according to the new and the standard method. STC counts the low cost and reduces the number of procedures needed for susceptibility testing.
Clarithromycin/*pharmacology
;
Culture Media
;
Humans
;
Microbial Sensitivity Tests/*methods
;
Mycobacterium avium Complex/*drug effects/isolation & purification
;
Tetrazolium Salts/*chemistry