1.Mistaken identity: Eumycetoma masquerading as Squamous cell carcinoma
Catherina Jessica Sutantoyo ; Johannes F. Dayrit ; Ma. Teresita G. Gabriel ; Glen Purnomo ; Reynaldo L. Ugalde
Journal of the Philippine Dermatological Society 2018;27(1):81-83
We report a case of eumycetoma in a Filipino patient who presented with a solitary reddish brown, moist, multinodular tumor on the
dorsum of the left foot of 2 years duration. Biopsy with Periodic acid Schiff (PAS) & Gomori methenamine silver (GMS) staining, fungal
culture, ultrasound and X-ray of the foot were done in our institution which confirmed the diagnosis of eumycetoma. The patient was
successfully treated with itraconazole 400/day for 3 months, followed by 200mg/day for the succeeding 9 months, leading to complete
resolution of the lesion leaving an atrophic hypopigmented scar. A high index of suspicion supported by diagnostic tests aided in the
early detection of the disease which also resulted to complete resolution of the disease.
Mycetoma
;
Mycoses
;
Itraconazole
2.CT and MR findings of mycotic infection of the paranasal sinus: differentiation from sinonasal neoplasm.
Kil Woo LEE ; Hyo Keun LIM ; Gwy Suk SEO ; Suk Soo BAE ; Shin Hyung LEE
Journal of the Korean Radiological Society 1992;28(2):176-181
When a soft tissue mass in the bony wall of the paranasal sinus is present, it is difficult to make a distinction between tumor and inflammatory mass on CT. Fungal sinusitis may have soft tissue attenuation on the bony wall of the sinus, bony sclerosis, focal bony destruction, and calcific area on CT. This is a report of four proven cases of fungal sinusitis, asperogillosis in 3 cases and mucormycosis in 1 case, All 4 patients had CT and one patient had MRI, On CT, bony sclerosis and destruction were well visualized in all cases. On MRI, mycetoma in the maxillary sinus was hypointense on T1 weighted images and more hypointense on T2 weighted images. Although CT appears to be the best modality for initial examination of the patient with sinusitis, the differentiation of fungal sinusitis from tumor mass or other entity may be better accomplished with MRI.
Humans
;
Magnetic Resonance Imaging
;
Maxillary Sinus
;
Mucormycosis
;
Mycetoma
;
Sclerosis
;
Sinusitis
3.Botryomycosis secondary to Staphylococcus simulans masquerading as mycetoma in a 46-year-old Filipino female.
Ysabel Regina H. ORTIZ ; Maria Christina Filomena R. BATAC
Acta Medica Philippina 2024;58(17):64-68
Botryomycosis is a rare pyogenic disease that presents with chronic suppurative and granulomatous skin lesions, commonly caused by Staphylococcus aureus. We report a case of botryomycosis presenting similarly to mycetoma, secondary to the emerging cutaneous pathogen Staphylococcus simulans. A 46â€Âyear-old female who previously worked in a wet market presented with a 13-year history of suppurative papules on a gradually enlarging right foot, and pain on ambulation. She had no systemic symptoms or co-morbidities, and does not recall preceding trauma. Physical examination showed brawny edema of the right foot with multiple sinus tracts draining purulent discharge. The clinical diagnosis at presentation was mycetoma. Magnetic resonance imaging showed a soft tissue mass involving the right foot and ankle with osseous destruction. Biopsy revealed suppurative granulomatous dermatitis; staining with Grocott methenamine silver did not highlight fungal elements. Potassium hydroxide mount of the purulent discharge did not show grains or hyphal elements. Tissue cultures showed growth of co-trimoxazole-susceptible Staphylococcus simulans. The patient was managed as a case of botryomycosis and treated with co-trimoxazole for 12 months. There was a significant decrease in right foot circumference along with scarring and resolution of associated pain. Repeat biopsy showed no evidence of infection. This is the first reported case of botryomycosis in the Philippines as well as the first report citing Staphyloccocus simulans as a causative agent. Botryomycosis is an important differential in patients clinically presenting as mycetoma. Animal pathogens may need to be considered as etiologic agents in at-risk patients with chronic subcutaneous infections.
Human ; Female ; Middle Aged: 45-64 Yrs Old ; Mycetoma
4.Localized Cutaneous Infection due to Scedosporium apiospermum.
Hyun Min NAM ; Sun Yong KWON ; Ui Kyung KIM ; Kun PARK ; Seok Don PARK
Korean Journal of Medical Mycology 2011;16(4):196-200
Scedosporium(S) apiospermum is the asexual stage of Pseudallescheria boydii. The organism has been isolated from polluted water, soil, sewage and potted plants in a hospital with low virulence. This ubiquitous fungus causes not only mycetoma, but also infections of variety of body sites including the skin. Localized skin infection without grain production due to this organism is much rarer than mycetoma. Infection may occur via direct inoculation and usually affects the extremities. We report a case of localized cutaneous infection due to S. apiospermum which occurred in a 79-year old female. She presented multiple erythematous papulopustules on the right wrist. Culture isolation for definitive diagnosis showed S. apiospermum. The patient was treated successfully with oral itraconazole 200 mg daily for 4 weeks.
Edible Grain
;
Extremities
;
Female
;
Fungi
;
Humans
;
Itraconazole
;
Mycetoma
;
Pseudallescheria
;
Scedosporium
;
Sewage
;
Skin
;
Soil
;
Wrist
5.A Case of Localized Skin Infection Due to Scedosporium Apiospermum.
Myung IM ; Hyun Woong KIM ; Young June SEO ; Jeung Hoon LEE ; Jang Kyu PARK ; Moo Kyu SUH
Korean Journal of Dermatology 2004;42(11):1505-1507
Scedosporium(S). apiospermum is the asexual stage of Pseudallescheria boydii. This ubiquitous fungus causes not only mycetoma but also infection of a variety of body sites including the skin. Localized skin infection without grain production due to this organism is much rarer than mycetoma. We report a case of cutaneous S. apiospermum infection which occured in a 75-year old female. She had multiple suppurative nodules with pustules on a dark red plaque at the dorsum of the right forearm. Cultural isolation for definitive diagnosis showed typical S. apiospermum. The patient was treated successfully with oral terbinafine 250mg daily for 1 week and oral itraconazole 200mg daily for 3 weeks.
Aged
;
Edible Grain
;
Diagnosis
;
Female
;
Forearm
;
Fungi
;
Humans
;
Itraconazole
;
Mycetoma
;
Pseudallescheria
;
Scedosporium*
;
Skin*
6.A Case of Cutaneous Scedosporium apiospermum Infection Successfully Treated with Voriconazole.
Hong Ki CHO ; Han Eul LEE ; Young Jin CHOI ; Sang Hoon LEE ; Kyu Uang WHANG ; Jong Suk LEE ; Sung Yul LEE
Korean Journal of Dermatology 2013;51(2):135-139
Scedosporium apiospermum, an asexual state of Pseudallescheria boydii, is a widely distributed mould that can be found in the soil, manure, stagnant water and decaying vegetation. It has become an emerging pathogen among immunosuppressed patients but it can also cause infections in immunocompetent patients by penetrating trauma. This fungus is a classical cause of mycetoma and the localized skin infections caused by this mould are much rarer than mycetoma. We report a case of cutaneous S. apiospermum infection in a 79-year-old woman. She had erythematous plaque with crust and violaceous supprative nodules on the right forearm. The culture from pus showed typical white to gray colored cottony colonies of S. apiospermum. Treatment was started with voriconazole effectively. Skin lesions completely cured with no reccurence. Thus, voriconazole shows to be an effective treatment for Scedosporium infection.
Female
;
Forearm
;
Fungi
;
Humans
;
Manure
;
Mycetoma
;
Pseudallescheria
;
Pyrimidines
;
Scedosporium
;
Skin
;
Soil
;
Suppuration
;
Triazoles
7.Infections Caused by Dematiaceous Fungi.
Korean Journal of Medical Mycology 2005;10(3):77-82
The dematiaceous fungi, characterized by having melanin in their cell walls, have become significant due to an increasing cause of human skin disease in Korea. The disease caused by dematiaceous fungi contain pityriasis (tinea) nigra, onychomycosis (in part), black piedra, keratomycosis (in part), chromoblastomycosis, phaeohyphomycosis, and eumycotic mycetoma (in part). Chromoblastomycosis is subcutaneous mycotic disease that contain sclerotic cells and histologically show pseudoepitheliomatous hyperplasia with microabscess, and phaeohyphomycosis is a group of mycotic infections that contain dematiaceous yeast-like cells, pseudohypae-like elements, hyphae or combination of these form in tissue.
Cell Wall
;
Chromoblastomycosis
;
Fungi*
;
Humans
;
Hyperplasia
;
Hyphae
;
Korea
;
Melanins
;
Mycetoma
;
Onychomycosis
;
Phaeohyphomycosis
;
Piedra
;
Pityriasis
;
Skin Diseases
8.A Case of Candida albicans Pneumonia Diagnosed by Endobronchial Biopsy.
Yerim PARK ; Eun Hee SONG ; Yoon Kyou PARK ; Haksoo KIM ; Jaemin LIM ; Gilhyun KANG ; Jun Hee WOO
Korean Journal of Medical Mycology 2015;20(3):76-81
Candida species is indigenous fungus of healthy individuals, and frequently found in sputum culture. Candida isolation from the respiratory tract is not generally considered as a marker of lung infection, and definitive diagnosis of Candida pneumonia is confirmed by tissue biopsy. A few cases of Candida pneumonia pathologically confirmed by transthoracic needle aspiration of mycetoma have been reported. In Korea, a case of Candida pneumonia diagnosed by bronchial washing and blood culture was reported, but there is no case report diagnosed by biopsy. We report a case of Candida pneumonia diagnosed by endobronchial biopsy, and antifungal therapy resulted in successful resolution of the pneumonia.
Biopsy*
;
Candida albicans*
;
Candida*
;
Diagnosis
;
Fungi
;
Korea
;
Lung
;
Mycetoma
;
Needles
;
Pneumonia*
;
Respiratory System
;
Sputum
9.Pseudomycetoma Due to Trichophyton schoenleinii Occurring in Two Brothers.
Kwang Hoon LEE ; Ki Bum MYUNG ; Sungnack LEE
Annals of Dermatology 1989;1(2):102-106
A 14-year-old boy and his 16-year-old elder brother, who had generalized tinea corporis for 1 and 3 years respectively, developed multiple discrete, non tender soft tumors on the scalp, forehead, neck and extremities. The boys were well nourished and had no systemic diseases. Histopathologic examination of the subcutaneous nodules revealed a well encapsulated granuloma containing lobulated granules characteristic of mycetoma; these granules consisted of septated fungal hyphae with vesicles. The dermatophyte isolated from the tumors was identified as Trichophyton schoenleinii.
Adolescent
;
Arthrodermataceae
;
Extremities
;
Forehead
;
Granuloma
;
Humans
;
Hyphae
;
Male
;
Mycetoma
;
Neck
;
Scalp
;
Siblings*
;
Tinea
;
Trichophyton*
10.Allergic Fungal Sinusitis: A Report of Two Cases.
Sea Yuong JEON ; Jong Pil BYUN ; Jae Yong KANG ; Jae Hong CHON
Journal of Rhinology 1998;5(2):155-159
Allergic fungal sinusitis (AFS) is a benign, noninvasive form of fungal sinusitis. Histologically, AFS is characterized by allergic mucin, which consists of eosinophilic mucinous material with occasional laminar deposits of eosinophils. A diagnosis of AFS can be made when there is a demonstration of characteristic allergic mucin and an appearance of fungal hypae scattered within the mucin with no evidence of tissue invasion, or when fungi cultures yield positive results. Until now, no cases of AFS have been reported in Korea, though there have been many cases of mycetomas and a few cases of invasive fungal sinusitis. We present the first two cases of AFS in Korea. The patients demonstrated characteristic allergic mucin, fungal hypae scattered within the mucin, and no evidence of tissue invasion on histopathology. Nasal polyps, involvement of the unilateral sinuses, peripheral eosinophilia, an elevated total IgE, and hyperattenuated masses observed in the CT supported the diagnosis of AFS. The patients recovered and did not display recurrence after surgery and treatment with topical steroids and saline irrigation.
Diagnosis
;
Eosinophilia
;
Eosinophils
;
Fungi
;
Humans
;
Immunoglobulin E
;
Korea
;
Mucins
;
Mycetoma
;
Nasal Polyps
;
Recurrence
;
Sinusitis*
;
Steroids