56 patients with sulfamide-related allergy were involved in this study. The results showed that almost members of sulfamide family that are used on clinical can cause allergic reactions. Among these, Biseptol and Trimazon are most common. Allergic reactions with sulfamides are delayed. Clinical manifestations of sulfamide allergy are severe with erythroderma, Stevens-Johnson and Lyell syndromes. Elevation of ESR, SGOT and SGPT levels is main laboratory findings. It is taken a long time to treat and solutions of glucocorticoid, Demerol, ascorbic acid are common medications.
Drug Hypersensitivity ; Pharmaceutical Preparations