1.Skin Findings in Newborns and Their Relationship with Maternal Factors: Observational Research.
Ozlem EKIZ ; Ulker GUL ; Leyla MOLLAMAHMUTOGLU ; Muzeyyen GONUL
Annals of Dermatology 2013;25(1):1-4
BACKGROUND: Cutaneous lesions are commonly seen in the newborn period and exhibit inconsistency from the skin lesions of an adult. OBJECTIVE: The present study was carried out with an aim to determine the frequency of physiologic and pathologic cutaneous findings in newborns. METHODS: Typically, 1234 newborns were included in this study. A questionnaire about maternal gestational history, maternal and family history was issued to the parents of each newborn. The presence of cutaneous lesions was recorded. RESULTS: Overall, 642 (52%) of the newborns were male and 592 (48%) were female. Typically, 831 newborns (67.3%) had at least one cutaneous lesion. The prevalence of genital hyperpigmentation and milia was significantly higher in males. In premature newborns, the pervasiveness of cutis marmorata and genital hyperpigmentation was found to be significantly higher. Caput succedaneum, transient neonatal pustular melanosis and cyanosis appeared predominantly in vaginally born infants. Erythema toxicum neonatorum was seen in infants, who were born by cesarean section. The predominance of Mongolian spots and erythema toxicum neonatorum were significantly higher in the newborns of the multiparous mothers; however, caput succedaneum was significantly higher in newborns of the primiparous mothers. CONCLUSION: A number of studies about neonatal dermatoses have been carried out involving different methods in various countries. We consider that our study may be useful in literature, as it has been carried out involving large number of maternal parameters.
Cesarean Section
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Cyanosis
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Erythema
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Female
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Humans
;
Hyperpigmentation
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Infant
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Infant, Newborn
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Male
;
Melanosis
;
Mongolian Spot
;
Parents
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Pregnancy
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Prevalence
;
Skin
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Skin Diseases
;
Surveys and Questionnaires
2.Two Cases of Unilateral Lichen Planus Following the Lines of Blaschko.
Derya YAYLA ; Seray KULCU CAKMAK ; Isil Deniz OGUZ ; Muzeyyen GONUL ; Esra OZHAMAM ; Aysel COLAK ; Ulker GUL
Annals of Dermatology 2014;26(5):636-638
A 50-year-old man and 71-year-old woman presented to our clinic with unilateral, linear, erythematous, pruritic lesions along the lines of Blaschko. On the basis of clinical and histopathological findings, the lesions were diagnosed as lichen planus with a Blaschkoian distribution, which is a rare form of lichen planus. The patients were treated with topical corticosteroids and antihistamines.
Adrenal Cortex Hormones
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Aged
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Female
;
Histamine Antagonists
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Humans
;
Lichen Planus*
;
Middle Aged
3.Clinical and Laboratory Findings of Pigmented Purpuric Dermatoses.
Muzeyyen GONUL ; Seray KULCU CAKMAK ; Nimet OZCAN ; Isil Deniz OGUZ ; Ulker GUL ; Zeynep BIYIKLI
Annals of Dermatology 2014;26(5):610-614
BACKGROUND: Pigmented purpuric dermatoses (PPD) are chronic, recurrent group of disorders characterized by petechial and pigmentary macules usually localized on the lower limbs. Its etiopathogenesis is unknown. There are very few clinical and etiological studies on PPD in the literature. OBJECTIVE: We aim to examine the etiopathogenetic factors of PPD retrospectively. METHODS: Demographic characteristics, history of co-morbid disorders and drug usage, hepatitis markers, levels of serum lipids, findings of Doppler ultrasonography in lower extremities, and patch test results of the 24 patients of PPD were examined retrospectively. The patch test results, history of drug use, and co-morbid disorders of the patients were compared with those of the control groups. RESULTS: The male-to-female ratio was 1 : 2, and 83.3% of the patients had Schamberg disease. Seventeen patients had co-morbid disorders and 16 used various drugs, but there was no statistically significant difference between the controls and patients. One patient was positive for hepatitis B surface antigen and 1, for anti-hepatitis C virus antibody. Nine had elevated total cholesterol levels, and 5 had elevated triglyceride levels. Further, 30% of them were positive for at least 1 allergen, while 16% of the control subjects were positive for at least 1 allergen, but statistically significant difference was not found between the 2 groups. Variable degrees of venous insufficiency were detected in 75% of the patients on Doppler ultrasonography of the lower extremities. CONCLUSION: Venous insufficiency and hypercholesterolemia might be the basic predisposing factors for PPD. Further studies are needed to show if diabetes mellitus and hypertension may cause perivascular inflammation in PPD.
Causality
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Cholesterol
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Diabetes Mellitus
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Hepatitis
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Hepatitis B Surface Antigens
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Humans
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Hypercholesterolemia
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Hypertension
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Inflammation
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Lower Extremity
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Patch Tests
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Pigmentation Disorders
;
Retrospective Studies
;
Skin Diseases*
;
Triglycerides
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Ultrasonography, Doppler
;
Vascular Diseases
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Venous Insufficiency