Objective:To observe the clinical effect of injecting hyaluronic acid fillers and Poly (p-dioxanone) (PPDO) absorption line in improving periorbital aging.Methods:From May 2017 to May 2019, 104 patients aged 20-55 (36±5) years were treated with combination of injection and PPDO; a score scale was developed based on the tear ditch aging, and beauty seekers were divided into two groups, 48 in mild and 56 in moderate, and followed up for 6-12 months after treatment.Results:Immediately postoperative satisfaction in the mild group was significantly higher than that in the moderate group, and ideal within 6 months. For 6 months after surgery, satifactoty score was (7.48±1.29) in the mild group and (6.32±1.03) in the moderate group; the treatment effect decreased over time.Conclusions:Based on the rheological characteristics of sodium hyaluronic acid gel and the anatomical characteristics of tear ditch formation, multi-point injection filling technique combined with small line to treat light and moderate orbital aging can achieve good clinical results.