1.Spinal Intradural Hematoma and Permanent Paraparesis after a Lumboperitoneal Shunt Operation: An Unusual Complication.
Recep BASARAN ; Mustafa EFENDIOGLU ; Fatih Han BOLUKBASI ; Sahin ASLAN ; Nejat ISIK ; Tuncay KANER
Asian Spine Journal 2014;8(4):516-520
Pseudotumor cerebri is a condition of increased intracranial pressure in the absence of clinical, laboratory or radiological pathology. Spinal intradural hematoma formation after lumboperitoneal shunt (LPS) implantation is very rare, but it can cause sudden and serious deterioration. In this report, we present a patient who developed an intradural hematoma following LPS operation. A 27-year-old male patient suffering from headaches and progressive vision loss was diagnosed with pseudotumor cerebri. He underwent LPS operation in January 2009. Four hours after the operation, he developed urinary and fecal incontinence with paraparesis (1/5). Lumbar magnetic resonance imaging identified an intradural hematoma at the level of L2-L3, and he was reoperated. The intradural hematoma was removed. Physical therapy was started because of paraparesis. Two months later, the patient's muscle strength had increased to 3/5. Surgeons must remember that, LPS implantation can cause a spinal intradural hematoma in a small percentage of patients, with catastrophic results.
Adult
;
Fecal Incontinence
;
Headache
;
Hematoma*
;
Humans
;
Intracranial Pressure
;
Magnetic Resonance Imaging
;
Male
;
Muscle Strength
;
Paraparesis*
;
Pathology
;
Polyradiculopathy
;
Pseudotumor Cerebri
2.Spinal Intradural Hematoma and Permanent Paraparesis after a Lumboperitoneal Shunt Operation: An Unusual Complication.
Recep BASARAN ; Mustafa EFENDIOGLU ; Fatih Han BOLUKBASI ; Sahin ASLAN ; Nejat ISIK ; Tuncay KANER
Asian Spine Journal 2014;8(4):516-520
Pseudotumor cerebri is a condition of increased intracranial pressure in the absence of clinical, laboratory or radiological pathology. Spinal intradural hematoma formation after lumboperitoneal shunt (LPS) implantation is very rare, but it can cause sudden and serious deterioration. In this report, we present a patient who developed an intradural hematoma following LPS operation. A 27-year-old male patient suffering from headaches and progressive vision loss was diagnosed with pseudotumor cerebri. He underwent LPS operation in January 2009. Four hours after the operation, he developed urinary and fecal incontinence with paraparesis (1/5). Lumbar magnetic resonance imaging identified an intradural hematoma at the level of L2-L3, and he was reoperated. The intradural hematoma was removed. Physical therapy was started because of paraparesis. Two months later, the patient's muscle strength had increased to 3/5. Surgeons must remember that, LPS implantation can cause a spinal intradural hematoma in a small percentage of patients, with catastrophic results.
Adult
;
Fecal Incontinence
;
Headache
;
Hematoma*
;
Humans
;
Intracranial Pressure
;
Magnetic Resonance Imaging
;
Male
;
Muscle Strength
;
Paraparesis*
;
Pathology
;
Polyradiculopathy
;
Pseudotumor Cerebri
3.Effect of Maternal Depression on Brain-derived Neurotrophic Factor Levels in Fetal Cord Blood
Erdem Onder SONMEZ ; Faruk UGUZ ; Mine SAHINGOZ ; Gulsum SONMEZ ; Nazmiye KAYA ; Mehmet Akif CAMKURT ; Zeynel GOKMEN ; Mustafa BASARAN ; Kazim GEZGINC ; Sami Sait ERDEM ; Hasan Haluk DULGER ; Erkan TASYUREK
Clinical Psychopharmacology and Neuroscience 2019;17(2):308-313
OBJECTIVE: We aimed to assess the association between cord blood brain-derived neurotrophic factor (BDNF) concentration and maternal depression during pregnancy. METHODS: A total of 48 pregnant women, admitted for elective caesarean section to Department of Obstetrics and Gynecology, The Konya Research and Training Hospital and Konya Necmettin Erbakan University Meram Medical Faculty, were included in this study. The study group included 23 women diagnosed as having depression during pregnancy and the control group included 25 pregnant women who did not experience depression during pregnancy. RESULTS: The groups had similar sociodemographic characteristics. Cord blood BDNF concentration was significantly lower in babies born to mothers with major depression as compared with those in the control group. We didn't find any correlation between the umbilical cord blood BDNF levels and BDI scores. CONCLUSION: The results suggest that the existence of major depression in pregnant women may negatively affect fetal circulating BDNF levels.
Brain-Derived Neurotrophic Factor
;
Cesarean Section
;
Depression
;
Faculty, Medical
;
Female
;
Fetal Blood
;
Gynecology
;
Humans
;
Mothers
;
Obstetrics
;
Pregnancy
;
Pregnant Women