1.Elevated Monocyte to High-density Lipoprotein Ratios as an Inflammation Markers for Schizophrenia Patients
Musa SAHPOLAT ; Duygu AYAR ; Mustafa ARI ; Mehmet Akif KARAMAN
Clinical Psychopharmacology and Neuroscience 2021;19(1):112-116
Objective:
Monocyte to high density lipoprotein ratio (MHR) is a new instrument for giving notice inflammation, which plays a main role in schizophrenia. Thus, in this study, our goal was to investigate the possible association between MHR and schizophrenia.
Methods:
The participants of this study consisted of 75 schizophrenia patients and 74 healthy individuals (control group).The Positive and Negative Syndrome Scale was used to collect data from the patient group. Complete blood count parameters and lipid profile were analyzed in all study participants.
Results:
The patients with schizophrenia had higher MHR values (15.04 ± 3.31 in schizophrenia patients and 12.62 ± 2.99 in controls; p = 0.001). Monocyte counts and MHR of the schizophrenia patients were significantly higher than the control group. There was a significant and positive correlation between age, body mass index, severity of disease and MHR.
Conclusion
To our knowledge, this study was the first to demonstrate inflammatory markers such as MHR levels in schizophrenia patients. Both monocyte counts and MHR values in schizophrenia patients were higher than the control group. MHR might be an available and useful inflammatory marker to evaluate inflammation in schizophrenia patients.
2.Diprosopus, craniorachischisis, arthrogryposis, and other associated anomalies in a stillborn lamb.
Cihan KACR ; Kadir OZCAN ; Ismet TAKCI ; Kutlay GURBULAK ; Hasan OZEN ; Musa KARAMAN
Journal of Veterinary Science 2008;9(4):429-431
Congenital malformations with multiple anomalies have been described infrequently in the veterinary literature. A stillborn male crossbred lamb with diprosopus, craniorachischisis, and arthrogryposis was examined macroscopically and histopathologically in this study. The left head was smaller than the right head. Micrencephaly, agnathia, and a rudimentary tongue, which was adherent to the palate, were present in the left head. Micrencephaly, brachygnathia superior, and cleft palate were present in the right head. Cerebellar agenesis and spinal cord hypoplasia were observed. The cerebrums and the spinal cord were covered with a tapering membranous structure. Neural and dermal tissues were noted to intervene upon microscopic examination of this structure. Disorganization of neurons was observed in both cerebrums, though it was more severe in the left one. This case demonstrates many congenital defects occurring together in a lamb.
Animals
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Congenital Abnormalities/pathology/*veterinary
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Male
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Sheep
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Sheep Diseases/*congenital/pathology
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Stillbirth