1.Metastasis of Non-Muscle-Invasive Bladder Cancer Into the Thyroid Gland: A Literature Review Accompanied by a Rare Case.
Murat TUNCER ; Gokhan FAYDACI ; Gokhan ALTIN ; Banu Atalay ERDOGAN ; Sermin KIBAR ; Arif SANLI ; Dilek BILGICI
Korean Journal of Urology 2014;55(3):222-225
Bladder cancer is the most prevalent malignancy of the urinary tract. About 90% of bladder cancers are urothelial carcinomas. Seventy percent of cases newly diagnosed are superficial diseases; roughly 30% of newly diagnosed cases are muscle-invasive metastatic diseases. Bladder urothelial carcinoma primarily metastasizes into regional lymph nodes and then into liver, lung, mediastinum, bone, and adrenal gland. In our case, non-muscle-invasive bladder cancer metastasized into the bone, mediastinum, iliac lymph node, and adrenal and thyroid glands. This is the first reported case in the current literature in which urothelial carcinoma metastasized into the thyroid gland.
Adrenal Glands
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Liver
;
Lung
;
Lymph Nodes
;
Mediastinum
;
Neoplasm Metastasis*
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Thyroid Gland*
;
Urinary Bladder Neoplasms*
;
Urinary Bladder*
;
Urinary Tract
2.Anatomy, Variants, and Pathologies of the Superior Glenohumeral Ligament: Magnetic Resonance Imaging with Three-Dimensional Volumetric Interpolated Breath-Hold Examination Sequence and Conventional Magnetic Resonance Arthrography.
Hayri OGUL ; Leyla KARACA ; Cahit Emre CAN ; Berhan PIRIMOGLU ; Kutsi TUNCER ; Murat TOPAL ; Aylin OKUR ; Mecit KANTARCI
Korean Journal of Radiology 2014;15(4):508-522
The purpose of this review was to demonstrate magnetic resonance (MR) arthrography findings of anatomy, variants, and pathologic conditions of the superior glenohumeral ligament (SGHL). This review also demonstrates the applicability of a new MR arthrography sequence in the anterosuperior portion of the glenohumeral joint. The SGHL is a very important anatomical structure in the rotator interval that is responsible for stabilizing the long head of the biceps tendon. Therefore, a torn SGHL can result in pain and instability. Observation of the SGHL is difficult when using conventional MR imaging, because the ligament may be poorly visualized. Shoulder MR arthrography is the most accurately established imaging technique for identifying pathologies of the SGHL and associated structures. The use of three dimensional (3D) volumetric interpolated breath-hold examination (VIBE) sequences produces thinner image slices and enables a higher in-plane resolution than conventional MR arthrography sequences. Therefore, shoulder MR arthrography using 3D VIBE sequences may contribute to evaluating of the smaller intraarticular structures such as the SGHL.
Adult
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*Breath Holding
;
Female
;
Humans
;
Imaging, Three-Dimensional/*methods
;
Ligaments, Articular/*anatomy & histology/pathology
;
Magnetic Resonance Imaging/*methods
;
Male
;
Middle Aged
;
Shoulder Impingement Syndrome/*diagnosis
;
*Shoulder Joint/injuries
;
Tendon Injuries/diagnosis
3.Molecular epidemiology of HIV-1 strains in the south-east and east of Turkey
elen Kemal Mustafa ; Sayan Murat ; Dal Tuba ; Ayaz Celal ; Tekin Alicem ; zekinci Tuncer ; Koruk Tekin Suda ; Barcin Tunga ; Tekin Recep ; Dal Sinan Mehmet ; Kalkanl Sevgi
Asian Pacific Journal of Tropical Biomedicine 2015;(9):743-747
To detect the subtype characterization and drug-resistant mutations in HIV-1 strains after the refugee movement from Syria to Turkey between 2011 and 2014 in south east border lines. Methods: A total of 65 patients were included in this study, of which 57 (88%) patients were antiretroviral therapy-naive patients. HIV-1 RNA was detected and quantified by real-time PCR assay. HIV-1 subtypes and circulating recombinant forms (CRFs) were identified by phylogenetic analysis (neighbor-joining method), and drug-resistant mutations were analyzed. Results: Three major HIV groups were indicated. Two of these groups were located in subtype B. The other group showed heterogeneity. Subtype B (48/65, 73.8%), followed by CRFs (12/65, 18.5%) was the most common strain. Subtype of CRFs consisted of CRF01_AE (9/65, 13.8%) and CRF02_AG (3/65, 4.6%). Subtype C (1/65, 1.5%), sub-subtypes A1 (2/65, 3.1%) and F1 (2/65, 3.1%) were also detected with low prevalence. The rate of overall primary antiretroviral resistance was 4.9% (3/61). Drug-resistant rate for non-nucleoside reverse transcriptase inhibitors was 4.9%. The thymidine analogue mutation rate was 13.1% (8/61). Conclusions: HIV molecular epidemiology studies are necessary to determine transmission patterns and spread. Subtype B and CRF01_AE, CRF02_AG are the most prevalent strains in the south-east of Turkey. However, subtype C, sub-subtypes A1 and F1 are of low prevalence but persist in the south-east of Turkey. In the near future, changing of HIV epidemiology will be possible in Turkey due to migration movement in border lines and resistance testing will play an important role in HIV management.
4. Molecular epidemiology of HIV-1 strains in the south-east and east of Turkey
Mustafa Kemal ÇELEN ; Celal AYAZ ; Alicem TEKIN ; Tuncer ÖZEKINCI ; Suda Tekin KORUK ; Recep TEKIN ; Sevgi KALKANLI ; Murat SAYAN ; Murat SAYAN ; Tuba DAL ; Tunga BARCIN ; Mehmet Sinan DAL
Asian Pacific Journal of Tropical Biomedicine 2015;5(9):773-777
OBJECTIVE: To detect the subtype characterization and drug-resistant mutations in HIV-1 strains after the refugee movement from Syria to Turkey between 2011 and 2014 in south east border lines. METHODS: A total of 65 patients were included in this study, of which 57 (88%) patients were antiretroviral therapy-naive patients. HIV-1 RNA was detected and quantified by real-time PCR assay. HIV-1 subtypes and circulating recombinant forms (CRFs) were identified by phylogenetic analysis (neighbor-joining method), and drug-resistant mutations were analyzed. RESULTS: Three major HIV groups were indicated. Two of these groups were located in subtype B. The other group showed heterogeneity. Subtype B (48/65, 73.8%), followed by CRFs (12/65, 18.5%) was the most common strain. Subtype of CRFs consisted of CRF01_AE (9/65, 13.8%) and CRF02_AG (3/65, 4.6%). Subtype C (1/65, 1.5%), sub-subtypes A1 (2/65, 3.1%) and F1 (2/65, 3.1%) were also detected with low prevalence. The rate of overall primary antiretroviral resistance was 4.9% (3/61). Drug-resistant rate for non-nucleoside reverse transcriptase inhibitors was 4.9%. The thymidine analogue mutation rate was 13.1% (8/61). CONCLUSIONS: HIV molecular epidemiology studies are necessary to determine transmission patterns and spread. Subtype B and CRF01_AE, CRF02_AG are the most prevalent strains in the south-east of Turkey. However, subtype C, sub-subtypes A1 and F1 are of low prevalence but persist in the south-east of Turkey. In the near future, changing of HIV epidemiology will be possible in Turkey due to migration movement in border lines and resistance testing will play an important role in HIV management.
5.Increase in transaminase levels during COVID-19 infection and its association with poor prognosis.
Oguz Kagan BAKKALOGLU ; Ugur ONAL ; Tugce ESKAZAN ; Enes Ali KURT ; Selcuk CANDAN ; Ridvan KARAALI ; Sermin BOREKCI ; Seval URKMEZ ; Yalim DIKMEN ; Fehmi TABAK ; Murat TUNCER ; Ibrahim HATEMI
Singapore medical journal 2023;64(10):640-644