1.Student’s satisfaction survey with implementation of the curriculum of “Biology”
Munkhjargal E ; Khishigjargal J
Mongolian Medical Sciences 2022;202(4):12-23
Background:
The purpose of this study is to investigate students' satisfaction whose were studying in the academic years 2020-2021, 2021 - 2022 with the biology curriculum at "Ach" Medical University, to evaluate the effectiveness of the teaching method, and to improve the planning and execution of future teaching and learning activities based on the students' perceptions.
Introduction:
One of the ways to evaluate the quality of services of higher education institutions is the student satisfaction survey. The satisfaction of any customer with the service that they receive depends on many factors. We conducted a survey on the satisfaction of students who are the main users of the Biology curriculum at Ach Medical University, and considered that it is necessary to pay further attention to the fact that the results taking and the requirements.
Purpose:
The purpose of this study is to take a survey of the satisfaction of the students of the biology curriculum of "Ach" Medical University based on the perceptions of the students, give an evaluation and conclusion about the teaching activities and improve the teaching quality and methodology.
Materials and Methods:
This research is based on the HEdPERF model Beaumont (2012) who has developed a model for evaluating the quality of higher education with 6 factors, each factor having 4 questions and 1-10 points. F of these factors were used in this research [12]. It includes:
1. Training-Lecture Quality, Seminar/Laboratory Quality, Teacher's Teaching Methodology, Importance of Course Content
2. Teacher-Professional knowledge and experience: Ability to support and help students, Recognize the needs of the students, Ability to attract student's attention in training, Communication skills
3. Organization and materiality of study - Organization, Management, Flexibility of the training, Quality, and Availability of training materials and equipment
In the academic year 2020-2021 and 2021-2022, students who studied biology were asked to evaluate the performance of the "Biology" curriculum by answering 30 questions with 3 groups of questions using Google form, and answering one of the points 1, 2, 3, 4, 5 for each question and collected the research material by clarifying.
General information of the research participants :
147 first-year students in "Ach" Medical University aged 17-20, 86.4% female and 13.6% male, or 29.4% of all students, participated in the survey.
:
Result
Teaching process of biology course:
The participants of the research who studied the biology course through combined online and classroom learning answered that the lecture course was conducted that explains the phenomenon broadly in a scientific unity. They answered that the method of lecturing is appropriate for explaining cases, repeating topics, clarifying interrelationships, the content and quantity of independent work, and practical importance if the tasks are completed.
Evaluation methodology of the teaching:
The participants said that the lessons are taught clearly, with real-life examples, communication between teacher and students is proper, independent work is checked promptly, the results reporting is done on time and the evaluation is as realistic.
When the teacher asks for corrections during class in the future:
The students said that if the teacher has more conversations with them, if the teacher speaks louder while taking classes, and some answered that there is nothing to correct.
Biology curriculum evaluation:
When asked about the environment for implementing the Biology curriculum and the availability of teaching materials, the students said it is moderate. In response to the question of describing the advantage and disadvantages of the Biology curriculum:
• The knowledge and skills of the teacher, as well as the opportunity to learn from other programs are an advantage
• Classrooms, equipment, and e-learning were evaluated as weaknesses.
Conclusion
1. According to the satisfaction survey results obtained from 147 students who are representatives of the students who studied Biology in the 1st year of 2021 and 2022 at "Ach" Medical University, it was concluded that the teaching process of biology is 84.8 percent or good.
2. In order to further improve the course's quality and results, and also each student's practice, it was determined that some changes to the ratio of the content of the lectures and seminars, in addition to attending practice classes regularly in the classroom and with mutual discussion, are required.
2.Insulin level and insulin resistance higher among people with metabolic syndrome
Batnaran D ; Enkhjargal A ; Munkhjargal J ; Odonguya N ; Munkhtsetseg J
Mongolian Medical Sciences 2013;163(1):7-10
IntroductionThe metabolic syndrome is a cluster of the most dangerous heart attack risk factors: diabetes andprediabetes, abdominal obesity, high cholesterol and high blood pressure. Also it is known as acluster of changes associated with resistance to insulin.There is a convincing evidence of important ethnic differences in the prevalence of metabolic syndrome,its components and sequelae. Estimates vary by country, but generally they show higher prevalenceof metabolic syndrome in non-European groups. Based on these findings, we were convinced inthe importance of studying the prevalence of metabolic syndrome and insulin resistance among thepopulation of Mongolia.Materials and MethodsThe main goal of our study was the determination of insulin level and insulin resistance in metabolicsyndrome exposed and non-exposed groups. We included 194 randomly selected people aged 20-60 years old; among them 51 had metabolic syndrome which was identified by the criteria of theInternational Diabetes Federation. All participants underwent general medical examinations andsigned a written consent paper. Fasting blood glucose, triglyceride, HDL, insulin levels were measuredin fasting blood serum and insulin resistance was calculated as a HOMA-IR model.ResultsAverage age of participants was 44,26±8,66 years, of whom 46,4% (n=90) were male, 53,6%(n=104)were female. By IDF criteria, 26,2% (n=51) of the participants had metabolic syndrome. Insulin levelwas 17,23±14,91μIu/mL in MS exposed group which was much higher than in the control group.Insulin, HOMA-IR, had direct correlation with the body mass, BMI and waist circumference andinverse correlation between HDL.Conclusions26.2% of the study participants had metabolic syndrome which was defined by IDF criteria. Insulin levelin the MS exposed group was 17,23±14,91μIu/mL, higher than in the control group by 7,53±2,21μIU/mL. Insulin, HOMA-IR, showed a direct correlation with the body mass, BMI and waist circumferenceand inverse correlation between HDL.
3.Effects of ketogenic diet on some metabolic parameters
Munkhtsetseg J ; Munkhjargal J
Mongolian Medical Sciences 2020;192(2):66-71
Diets, boosting circulating ketones are used to use for treating some neurological disease. But recent
years it’s usage in coordinating the weight is becoming more popular among overweight population.
Weight loss is being offered as a therapy is aimed to reduce some risk factors of metabolic syndrome.
Ketogenic diet offers high amount of fat in food composition and very low amount of carbohydrate.
Results regarding the impact of ketogenic diet on cardiovascular risk factors and metabolic parameters
are controversial and seem to be limited in time, which means it depends on lasting time of ketogenic
diet. Ketogenic diet is not totally safe and can be associated with some beneficial and adverse effects
on metabolism.
4.Utilizing lactic acid bacteria for the cultivation of health-safe vegetables
Anuujin G ; Munkhjargal B ; Tsend-Ayush D ; Gerelmaa E ; Baigalmaa J
Mongolian Journal of Health Sciences 2025;88(4):67-70
Background:
Research on lactic acid bacteria has confirmed how specific strains possess probiotic properties and impart unique sensory characteristics to food products. The use of probiotic lactic acid bacteria in many food products, thus confers various health benefits to humans when they are frequently consumed in adequate amounts.
Aim:
To determine the effect of lactic acid bacteria on the growth of tomatoes.
Materials and Methods:
The lactic acid bacteria were cultured using the Lactobacillus medium from whipping cream
and Dandelion (Taraxacum mongolicum) and identified using the MALDI-TOF MS automated microbial identification
analyzer. A solution was prepared using Lactobacillus delbrueckii isolated from whipping cream and Lactobacillus gasseri isolated from Dandelion (10^7CFU/ml), and sterilized tomato seeds were watered for 10 days with the solution, while
sterilized distilled water was used as a control. The germination rate of the seeds and the root length were measured and
recorded every day.
Results:
The solution of L.delbrueckii bacteria isolated from cream germinated 100% of the seeds, which is 4% higher
than the control seeds, while the solution of L.gasseri bacteria isolated from Dandelion germinated 100%, supporting 4%
higher than the control seeds. Seedlings irrigated with the L.delbrueckii bacterial solution exhibited an average length of
10.3cm, which was 1.3cm longer than the control (P=0.003), indicating a statistically significant difference. Similarly,
those treated with the L.gasseri solution had an average length of 11.5cm, 2.5cm longer than the control (P=0.005), also
demonstrating statistical significance.
Conclusion
The application of the lactic acid bacterial solution significantly enhanced both the germination of tomato
seeds and the growth of the plants compared to the control solution.
5.Assessment of Prebiotic Activity of Xylooligosaccharides Extracted from Food Industry By-Products via Microwave assisted enzymatic hydrolysis
Odgerel Ch ; Purevdulam E ; Anuujin G ; Buyankhuu T ; Munkhjargal B ; Battogtokh Ch ; Munkhtsetseg J
Mongolian Journal of Health Sciences 2025;86(2):183-190
Background:
This study explores the potential of food industry by-products, such as plant peels, stems, and slags, as
valuable sources of lignocellulosic material (LCM), which contains 25-40% xylan. These underutilized resources, often
discarded as waste, hold the promise of sustainable applications in biotechnology. By safely extracting xylooligosaccharides
(XOS) from LCM biomass, the value of these materials can be significantly enhanced, contributing to green production
and supporting sustainable development. XOS, recognized for its prebiotic activity, has been shown to promote the
growth of beneficial gut bacteria, making it a vital research area in the fields of food science, medicine, and technology.
Aim:
To extract and characterize oligosaccharides derived from by-products of the food industry, evaluate their physicochemical
properties, and investigate selected biological activities.
Materials and Methods:
This study utilized microwave pretreatment and enzymatic hydrolysis to isolate and purify
XOS from wheat bran and brewers’ spent grains (BSG), provided by Altan Taria LLC and APU CoL, respectively. Microwave
irradiation at 200°C for 5 minutes was employed as a pretreatment step, followed by hydrolysis using commercial
xylanase (Thermomyces lanuginosus, recombinant Aspergillus oryzae, 2500 BXU/g) at 55°C for 24 hours. The resulting
hydrolysate underwent filtration with activated carbon and ethanol precipitation to yield purified XOS. Analytical methods,
including FTIR spectroscopy, TLC and HPLC, were used for structural and compositional analysis of the purified
oligosaccharides. In vitro tests evaluated the ability of XOS to support the growth of beneficial gut bacteria, including
Bifidobacterium spp., Lactobacillus fermentum (ATCC 9338), and Lactobacillus casei (ATCC 344), using XOS-enriched
media. Additionally, in vivo studies were conducted on rats to determine the biological effects of XOS on gut microbiota.
Results:
The results demonstrated that prolonged enzymatic hydrolysis for more than 10 hours, using 0.25 g of xylanase
per 100 g of substrate, resulted in optimal yields. XOS purity was measured at 87.6% with an 8.1 g yield from wheat bran
and 89% purity with a 7.2 g yield from brewers’ spent grains. Structural analysis confirmed the presence of xylobiose,
xylotriose, and xylotetraose, with xylotetraose being the most abundant component in WBP-XOS (47.5%), and xylobiose
dominating BGS’s derived XOS (47.8%). Biological effects revealed that wheat bran-derived XOS significantly supported
the growth of Bifidobacterium spp. and L. fermentum (ATCC 9338) in a concentration-dependent manner, whereas
no significant effect was observed on L. casei (ATCC 344). In vivo studies confirmed that XOS consumption increased
populations of Bifidobacterium spp. and Akkermansia muciniphila spp. in gut microbiota (p<0.05). Furthermore, XOS
consumption reduced plasma cholesterol, triglycerides, and LDL-C levels while increasing HDL-C levels, demonstrating
metabolic benefits.
Conclusion
This research establishes that XOS with prebiotic activity can be efficiently extracted and purified from food
industry by-products using microwave-assisted enzymatic hydrolysis. This approach highlights the potential of utilizing
agricultural and industrial waste for producing functional prebiotics, contributing to sustainable practices and offering
valuable applications in health and nutrition.
6.The evaluation of immunosuppressive regimens in kidney transplant Mongolian recipients
Sarantsetseg J ; Byambadorj B ; Byambadash B ; Munkhjargal B ; Tumurbaatar B ; Jambaljav L ; Bayan-Undur D ; Ganbold L ; Chuluunbaatar D ; Oyunbileg B ; Batbaatar G ; Munkhbat B ; Nyamsuren D
Health Laboratory 2019;9(1):21-27
Background:
However kidney transplantation has being performed in Mongolia since
2006, because of pre-transplant sensitization, ABO incompatibility, hepatitis B and C virus
activation many patients are taken kidney transplantation in abroad. The transplantation
centers use own immunosuppressive regimens.
Objective:
Our aim was to assess the immunosuppressive regimens efficacy and toxicity
in kidney transplant Mongolian recipients.
Methods:
We analyzed data from 96 adult kidney transplant recipients who had taken
kidney transplantation in different transplant centers from August 2006 through January
2014. There were 3 kinds of regimens Group I Simulect induction with standard triple
/FK506/CyA+MMF/AZA+steroid/, Group II Campath-1H induction with CNI monotherapy
and Group III Campath-1H induction with standard triple /FK506/CyA+MMF/AZA+steroid/.
We retrospectively collected the post-transplant first two years serum creatinine. The study
was performed in 2014. The questionnaire was taken and blood samples collected for
determination of tacrolimus through level and for other laboratory tests. The primary end
point was the first two years serum creatinine, the secondary end points included rejection
episodes, blood through level of tacrolimus and some laboratory findings.
Results:
The post-transplant first two years serum creatinine levels were significantly
different in 3 groups. Group III showed similar results compared to Group I. There was not
enough data of biopsy proven acute rejection episodes however group II said more
rejections occurred. However participants said that rejection occurred in 15 (15.6%) biopsy
was done only 3 (3.1%) cases. Blood through level of tacrolimus was significantly different
in three groups. Some laboratory findings showed different between three groups.
Conclusions
A regimen of Campath-1H induction with CNI monotherapy (Group II) may
be advantageous for short-term renal function and cost effective but there were more
rejection complications and increased creatinine. The regimen of Campath-1H induction
11 with standard triple (Group III) may be advantageous for long-term renal function, allograft
survival, but there should consider about infection complications and polycythemia.
Simulect induction with standard triple could be best choice but transplantations were
performed in experienced centers. The study enrolled few cases and cases which were
performed at the beginning of transplant program so many things could influence on the
result. The study was compared beginner transplant center with experienced centers.
Longitudinal cohort study needed in the future.