1.Some result of the study of relationship between spread of animals containing of plague and climate change at the ugalz mountains
Sumiyabazar N ; Munkhbat O ; Batjav D ; Delgermaa T
Mongolian Medical Sciences 2013;164(2):11-18
Climate: Studies show that it is get warmer 2.10C in Mongolia in last 40 years. It influences ecology and decreased ecology event, succession action in ecosystem. It is interesting to study how climate change damage animal’s biology and ecology. The survey on changing ecology is rare conducted in Mongolia. Year average air temperature in Govi-Altai province got warmer 1.20C in last 30 years. Monitoring agency for meteorology and environment of Govi-Altai aimag summarized air temperature 1980-2009 (4-9 months) and it is got warmer 2.00C in Tonkhil soum.Plants: According to our research, at the above sea level around 2229-2600m dry steppe, at a.s.l 2601-2800m in steppe and water-meadow steppe at a.s.l 2801m high mountain steppe, zone plants grow. At the report of research for motion and episodic in epicenter of the marmot plague (1987-1991) aspect of plants figure by J.Batbold warm weather influence plants grow at around 100m.Animal spreading: In 1987-1991 M.sibirica spread almost part, S.erythrogenus above sea level 2300m in Ugalz mountains. Places where marmots live don’t have any marmots such as Alagiin hooloi, number of marmot is dramatically decreasing last years. It is related to climate change and hunting. Plants are changed due to influence climate animals in desert, dry steppe spread in Ugalz mountains and above sea level 2550m S.erythrogenus are according to the research, E.luteuse are spreading in front area of the Ugalz mountains, S.erythrogenus are spreading back of the Ugalz mountains.
2.Risk factors for ischemic stroke among Mongolian population
Gansuvd O ; Chimeglham B ; Oyungerel B ; Punsaldulam B ; Khandsuren B ; Sarantsetseg T ; Bolormaa D ; Erdenechimeg Ya ; Munkhbat B ; Baasanjav D
Mongolian Medical Sciences 2018;186(4):23-30
Background:
Stroke is a leading cause of death and disability, especially in low-income and middle-income countries and it impacts a tremendous medical, emotional and fiscal burden on society. Due to advances in Western healthcare, the prevalence of stroke since 1970 has decreased by 42%, whereas it has more than doubled in low-income to middle-income countries.
Stroke is a heterogeneous, multifactorial disease regulated by modifiable and nonmodifiable risk factors. Approximately 80% of stroke events could be prevented by making simple lifestyle modifications. In fact, nationwide characterization of well-known stroke factors in all social backgrounds is essential, however; populations can differ significantly not only in their socio-behavioral, legal, and geographical conditions, but also from other, historically understudied. Therefore, it is crucial to determine characterization of risk factors for ischemic stroke among Mongolian population.
Objective:
To determine etiology and risk factors for ischemic stroke among Mongolian population
Material and methods:
Our study was conducted by case-control study design. Cases were patients with acute first stroke; controls were matched with cases, recruited in a 1.2:1 ratio, for age and sex. The case series study was conducted in Stroke center of Third State Central hospital from January 2017 to December 2017. Structured questionnaires were administered and physical examinations were done in the same manner in cases and controls. Self-reported history of hypertension and diabetes mellitus or blood pressure of 140/90 mm Hg and blood sugar 6.4 mmol/L or higher was used to hypertension
and diabetes mellitus, respectively. Smoking status was defined as never, former, or current smoker. Alcohol use was categorized into never or former, low intake, moderate intake, and high or episodic heavy intake. Atrial fibrillation was based on previous history, review of baseline electrocardiograph results (for cases and controls). Odds ratios (OR) and logistic regression were calculated, with 95% confidence intervals.
Results:
In total, 173 patients with ischemic stroke and 146 controls were included. The patients’ age ranged from 17 to 92, the mean age was 61.2. Ischemic stroke more frequent in man than women by 27.4%. Previous history of hypertension or blood pressure of 140/90 mm Hg or higher (OR 2.40, 95% CI 1.48-3.88), diabetes mellitus (OR 3.08, 95% CI 1.44-6.57), hyperlipidemia (OR 5.09, 95% CI 2.64-9.82) atrial fibrillation (OR 8.70, 95% CI 2.01-37.64 ), current smoking (OR 2.07, 95% CI 1.26-3.40), alcohol consumption (OR 4.75, 95% CI 2.58-8.73) were all significantly associated with ischemic stroke. The mean age was lower in patients with stroke of other determined etiology. The frequency of hypertension was higher in patients with lacunar infarct than other subtypes. Smoking was high frequent in patients with large artery atherosclerosis.
Conclusion
6 potentially modifiable risk factors were collectively associated with ischemic stroke and were different among ischemic stroke subtypes. The odds ratios of these risk factors are higher than other countries’ study.
3.Significance of evaluation of D-dimer in COVID-19 patient: Case report
Bayarjavkhlan Ch ; Battulga Ch ; Buyanjargal E ; Byambalkham B ; Jargal-Erdene B ; Naranmandakh D ; Munkhsaikhan B ; Munkhbat T ; Oyungerel S ; Enkhnomin O ; Gantuya L ; Ulziitsetseg Ts
Health Laboratory 2021;14(2):23-32
Introduction:
Coronavirus infection 2019 (Ковид-19) is an infection caused by a novel virus and induces severe ARDS. КОВИД-19 pandemic has rapidly spreaded in 221 countries, 245,373,039 cases and 4,979,421 mortalities have been reported. Pulmonary and renal thrombotic angiopathy occur in patients with complications of ARDS, sepsis, and multi-organ failure. Elevated D-dimer in КОВИД-19 patients has been reported firstly by doctors in Wuhan, China. In addition, many studies have revealed that elevated D-dimer has been associated with the severity of the diseases, an increased rate of poor prognosis.
Objective:
We aim to determine D-dimer in КОВИД-19 patients, and patient condition a decrease of D-dimer level after administration of anticoagulant therapy.
Case report:
We introduce a rare case of КОВИД-19. Laboratory test results and the effect of anticoagulant therapy have been evaluated during the infection. 85 aged women were admitted with a diagnosis other than КОВИД-19. PCR for SARS-Cov-2 was negative on the previous day of admission, and Sars-Cov-2 Ag rapid test was also negative on the admission day. However, the D-dimer test result was much higher with 7120 ng/мл and X-ray and CT revealed a similar pattern to the КОВИД-19 patient. Then anti-Sars-Cov-2 test was positive with 4,08 COI. Based on laboratory test results of D-dimer, LDH, CRP, and CT pattern the patient was diagnosed with post-КОВИД-19 pneumonia, and anticoagulant therapy was initiated additionally to prevent hypercoagulation induced by КОВИД-19. D-dimer test taken before administration of anticoagulant therapy increased more to 10910 ng/мл. 3 days later D-dimer level decreased to 8180ng/мл and the patient’s condition was improved.
Conclusion
The evaluation of D-dimer of the patients with КОВИД-19 is highly significant. Anticoagulant therapy might be necessary for КОВИД-19 patients with high D-dimer level in serum. Further studies are needed to assess the long-term outcome of the illness and mortality.