BACKGROUND: To highlight from the varies researches, made by global scientists, about principle for students’ studying procedure, that students get enough information from the environment, habitation, media of communication before they run into school. It’s very important that students’ occupied knowledge and practice should be based on their daily life, associated with their future job, real requirement, and interest. The learner should be not only a knowledge owner, but also a knowledge creator to have a self-educated skill based on an activity. Most medical students encounter with high pressure in their first school year, and it has a high risk to drop their school at their first year, such as in Scotland 9.9% (Scotsman, 2010), in Australia 33% (Hinde, 2008) in Southern Africa 40% (Macgregor, 2007). We chose this article in our research to study the psychology of the premedical training students and to determine if it has the relevance with educational achievement. METHODS: The research has done with instant analytical research paper sample, and got a standard survey about adaptation and psychological changes in the 1st course of premedical training of medical school. After identifying the normal distribution of variables, we considered the differences between indexes with percent variables with Chi-Square distribution method, and differences between averages with T-Test methods, and also it could have true probability statistic if the meaning of “p” reaches less than 0.05. We have sum up the quality research data by their content groups. RESULT: The overall number of students, who has been involved in our survey, has reached 106 and from the ratio of genders and 1st, 2nd term’s GPA, we can analyze that without gender differences the students’ GPA has been improved in the 2nd term. The highest value of the students’ GPA was 1.47 and increased from C (2.49) mark to A (3.22) mark. The comparison of the 106 students’ valuation of their social adaptation by themselves in the first and second term, who has been involved in our survey, has shown that the highest value of the first term was 18.85, which the question was “How many times have you missed your class in last 2 weeks?” and the answer of the same question in the end of the second term has decreased to 1.11 average meaning, which shows that the students’ attitude for missing classes has decreased. The ratio of total number of students’ evaluation of social adaptation and 1st, 2nd term’s GPA, has been shown positive ratio of the GPA to the social adaptation, which was counted by Correlation formula. CONCLUSION: According to the students, who has involved in our study, have elevated their 2nd term GPA than 1st term, The adaptation of the students, who is studying in premedical training of the medical school, have been improving in the end of the school term, It’s giving a positive relevance between social adaptation and GPА of the students, who is studying in premedical training of the medical school.