Objective:To explore the effect of independent E purchasing skill training on social function rehabilitation of long-term inpatients with schizophrenia.Methods:A total of 42 inpatients with schizophrenia was divided into control group (22 cases) and experimental group (20 cases) by the random number table method. The control group was treated with traditional routine nursing and drug therapy, while the experimental group was treated with independent E purchasing skills training and drug therapy. The curative effect was evaluated by the Positive and Negative Syndrome Scale (PANSS), General Self-Efficacy Scale (GSES), Scale of Social function in Psychosis Inpatients (SSPI) before the intervention and at the end of the 12th week of intervention.Results:After 12 weeks intervention, the total score of PANSS in the experimental group was (44.60 ± 5.68), of which the positive symptom was (8.50 ± 1.47), the negative symptom was (11.90 ± 2.79) and the general psychopathology was (24.05 ± 3.02). In the control group, the scores of each type were (58.95 ± 9.62), (10.36 ± 3.67), (18.00 ± 4.67) and (30.59 ± 5.13). The difference between the two groups were statistically significant ( t values were -5.810- - 2.119, P<0.05). After 12 weeks intervention, the score of GSES in experimental group was (3.45 ± 0.48) and in control group (2.29± 0.69), the difference was statistically significant ( t value was 6.256, P<0.05). After 12 weeks intervention, the total score of SSPI was (38.90 ± 2.72), the score of the subjects' ability of daily living was (10.95 ± 1.19), the mobility and communication (15.45 ± 1.57), social activity skills (12.00 ± 1.34) in the experimental group. The scores of each type were (25.32 ± 6.36), (8.36 ± 1.59), (9.95 ± 2.75) and (7.00 ± 2.56) in the control group, the differences were statistically significant ( t values were 5.918-8.513, P<0.05). Conclusions:Independent E-purchasing skills training can improve the mental symptoms of long-term inpatients with schizophrenia, improve the self-efficacy and social function of inpatients with schizophrenia, and promote the rehabilitation of social function.