BACKGROUND:Inflamed dental pulp stem cells are a new kind of dental pulp stem cells, and there is no systematic review on the cells by now. OBJECTIVE:To systematical y review the research progress in inflamed dental pulp stem cells. METHODS:A computer-based online search in PubMed, Web of Science, CNKI, WanFang and VIP databases was performed for related articles published from the establishment of the databases to February 2014. The keywords were“(pulptis or inflam*dental pulp*or human dental pulp with irreversible pulpitis) and stem cel*”in English and Chinese, respectively. Hand searching was also done to obtain further information or papers about the studies. The results were qualitatively analyzed to comprehensively summarize the progress in the research of inflamed dental pulp stem cells. RESULTS AND CONCLUSION:Total y 11 papers were involved in result analysis that comprehensively review the research progress in inflamed dental pulp stem cells at the fol owing aspects:the research of history, material origin, cellculture, cel-surface markers, proliferation ability, multi-directional differentiation potential, animal models and clinical use. Researches of inflamed dental pulp stem cells are stil in the initial stage, and cultivating conditions and the establishment of animal models are stil in the exploratory phase. Controversies stil exist in the capacity of proliferation and multi-directional differentiation of the inflamed dental pulp stem cells. And fewer studies have been done in the characteristics of immunity, subpopulation and clinical use of the inflamed dental pulp stem cells.

ObjectiveTo systematically evaluate whether Tai Chi exercise is more effective than other exercise interventions in reducing the incidence of falls, improving the balance ability and reducing the fear of falls in older adults. MethodsLiteratures about Tai Chi exercise for older healthy adults in PubMed, EMBASE, Web of Science, the Cochrane Library, CNKI, Wanfang database and VIP database were searched from establishment to September, 2021. After literature screening, data extraction and literature quality evaluation independently were conducted by two investigators, meta-analyses were performed using Review Manager 5.3. ResultsA total of twelve randomized controlled trials including 1 366 elderly patients were included in the analysis. Compared with other ecercise intervention, Tai Chi exercise reduced the rate of falls among older adults (RR = 0.54, 95%CI 0.42 to 0.68, P < 0.001). Tai Chi exercise was superior to other ecercise intervention in terms of single leg standing time (MD = 9.57, 95%CI 6.19 to 12.94, P < 0.001) and functional reach distance (MD = 2.16, 95%CI 1.31 to 3.01, P < 0.00001). However, there was no significant difference in the improvement of fear of falling, Timed 'Up and Go' Test between Tai Chi exercise and other ecercise intervention modalities (P > 0.05). ConclusionTai Chi exercise is more advantageous than other ecercise intervention modalities in reducing the rate of falls and improving static balance ability among older adults, however, there is insufficient evidence that Tai Chi exercise is more effective in reducing fear of falling and improving dynamic balance ability.

ObjectiveTo investigate the effects of different cultivation modes on the yield of Gentiana crassicaulis and its microbial diversity and secondary metabolite content in the rhizosphere soil. MethodWith G. crassicaulis of different cultivation modes and its rhizosphere soil as the research objects， the composition of bacterial and fungal communities， dominant bacteria， and differential microorganisms in the rhizosphere soil were analyzed by high-throughput sequencing technology. HPLC was used to determine the content of iridoids in G. crassicaulis with different cultivation modes. ResultCompared with plastic film mulching， planting without mulch and intercropping of peony， white kidney bean， potato， and corn increased the yield of fresh products by 16.11%-17.68%， 22.48%-26.34%， 29.37%-32.19%， 34.82%-36.57%， and 35.34%-39.71%， respectively， and increased the yield of dry products by 19.75%-23.17%， 25.86%-29.32%， 30.18%-34.94%， 35.22%-39.87%， and 39.72%-43.73%. The total content of four iridoids， including gentiopicrin， loganic acid， sweroside， and swertiamarin， increased by 10.17%-37.83%， 5.93%-47.44%， 9.09%-28.84%， and 10.71%-28.57%， respectively. The diversity of bacterial and fungal communities in the rhizosphere soil increased significantly （P<0.05）. The relative abundance of pathogenic bacteria such as Sordariomycetes， Leotiomycetes， Tremellomycetes， Eurotiomycetes， Fusarium， and Cladophialophora decreased， and the proportions of beneficial bacteria such as Proteobacteria， Acidobacteria， and Actinobacteriota increased and they gradually became the dominant bacteria. ConclusionDifferent cultivation modes can affect the yield of G. crassicaulis and its microbial diversity and iridoid content in the rhizosphere soil. Cultivation without mulch and intercropping patterns have certain advantages， which can provide theoretical references for the planting of G. crassicaulis.