Objective: To explore the association between preeclampsia/eclampsia and maternal and fetal angiotensinogen SNPs. Methods: From January 2008 to October 2015, a case-parents/mother-control designed study was conducted among 347 preeclampsia/eclampsia cases and 700 controls to collect related information on their demographic characteristics and to detect the related angiotensinogen SNPs’ genotypes. Both log-linear and unconditional logistic regression methods were employed to investigate the genetic effects of maternal/fetal angiotensinogen SNPs on preeclampsia/eclampsia. Multivariate binary unconditional logistic regression model and covariance were used to analyze the relationship between BMI before pregnancy, weight gain during pregnancy and overweight and obesity in preschool children. Results: Both fetal angiotensinogen rs3789679 GA and AA genotype were associated with the reduced risks of preeclampsia/eclampsia, with ORs as 0.73 (95%CI: 0.55-0.96) and 0.62 (95%CI: 0.39-0.98), respectively. For fetal angiotensinogen rs2493132, individuals that carrying the TT genotype, presented a positive association with the risk of preeclampsia/eclampsia, with OR as 1.60 (95%CI: 1.08-2.37). However, these associations were not statistically significant after the correction of the false discovery rate. It was observed that fetal rs3789679 could reduce the risk of preeclampsia/eclampsia (OR=0.73, 95%CI: 0.55-0.96) under the dominant model (GA+AA/GG) while fetal rs2493132 increased the risk of preeclampsia/eclampsia (OR=1.66, 95%CI: 1.13-2.44) under the recessive model (TT/CC+CT). Maternal rs5051 presented an association with preeclampsia/eclampsia (OR=1.33, 95%CI: 1.01-1.76) under the dominant model (TC+CC/TT). Conclusions Results from the dominant model showed that both fetal rs3789679 GA and AA genotype reduced the risk of preeclampsia/eclampsia and maternal rs5051 TC while CC genotype increased the risk of preeclampsia/eclampsia. Fetal rs2493132 TT genotype seemed to be associated with the risk of preeclampsia/eclampsia under the recessive model.

Objective To investigate prevalence and influencing factors of post-traumatic stress disorder (PTSD) and anxiety of soldiers to provide clinical evidences in improving their psychological health. Methods A total of 168 soldiers from Inner Mongolia Autonomous Region in November 2016 were selected using cluster sampling. PTSD was assessed by Post-Traumatic Stress Disorder Scale (PCL-C). Anxiety was assessed by Self-Rating Anxiety Scale (SAS). Related factors of PTSD and anxiety were analyzed by correlation analysis. Multiple regression analysis was used to explore predictive indexes of anxiety. Results A total of 155 vulid samples were selected amung 168 soldiers in total in this study. Among 155 soldiers, the positive rate of PTSD was 14.2%; the positive rate of anxiety was 16.1%, and 36.4% of PTSD patients were accompanied with anxiety. PTSD and anxiety symptoms were positively associated with age (P<0.05), and negatively associated with objective support, support utilization, relationship with family and relationship with others (P< 0.05). Multiple regression analysis showed that support utilization, relationship with family and relationship with others could predict the severity of anxiety (F=14.895, P<0.01). Conclusions The occurrence of PTSD and anxiety are higher in soldiers. PTSD is more likely to be accompanied with anxiety, and the related factors of PTSD and anxiety are the same. The higher comorbidity of these two diseases may be due to the shared related factors of them, which emphasizes the importance of assessing and treating anxiety and PTSD at the same time to achieve better outcomes.

Objective To investigate the prevalence of post-traumatic stress disorder (PTSD) in the army and the effects of social support and interpersonal relationship on PTSD, so as to provide basis for understanding the mental health level of the army and further interventions.Methods Purposive sampling was performed to select the soldiers of one field army in Inner Mongolia Province from July to August 2016. According to the post-traumatic stress disorder scale civilian version (PCL-C), the soldiers were divided into experimental group and control group. Social support rating scale (SSRS) and self-made demographic questionnaire were used for evaluation in the study.Results The scores of objective support, support utilization, family relationship and relationship with others in the soldiers in the experimental group decreased compared to the control group, whereas statistically significant difference was observed (t=2.235,3.544,2.477,2.485;P<0.05). The severity of PTSD was significantly negatively correlated with the scores of relationship with others (r=-0.458, P=0.032), but not correlated with objective support, support utilization and family relationship (P>0.05). Conclusions Low objective support and support utilization, poor family relationship and relationship with others can result in a higher prevalence of PTSD,but the severity of PTSD is only negatively related to the scores of relationship with others.