No abstract available.
Diagnosis* ; Mucocutaneous Lymph Node Syndrome*

No abstract available.
Diagnosis* ; Mucocutaneous Lymph Node Syndrome*

No abstract available.
Diagnosis, Differential* ; Mucocutaneous Lymph Node Syndrome*

Background:Kawasaki is acute fever disease with systematic vein infection which often seen in children under 5 years old. Objectives:Describe the clinical characteristics and laboratory, echocardiography data in children with Kawasaki between early diagnosed group and late one. Subjects and method: A descriptive, prospective study was carried out on 77 Kawasaki disease patients were selected, including 50 patients were diagnosed before day 10 of illness (group 1) and 27 patients were diagnosed on or after day 10 (group 2) in the National Pediatrics hospital from June 2004 to June 2006. Results:The mean was 13.4 months. Age under 12 months was 61 %. Male/female ratio was 1.7: 1. Fever, red lips, red eyes, skin rash, extremities edema and cervical lymphadenopathy occurred in the first week. The inflammatory response was strong (CRP: 83.6 mg/I, erythrocyte sedimentation rate (ESR) after an hour: 79.1 mm. WBC: 27800/ mm3). There were no differences between patients in the group 1 and group 2 in age, gender, time to the first medical visit, C-reactive protein (CRP) concentration, white blood cell count or erythrocyte sedimentation rate. Patients in the group 1 had significantly close clustering of symptoms onset in the first few days of illness, but patients in the group 2 had onset of symptoms scattered over 4 days. A platelet count of over 500.000/mm3 occurred more often in the group 2 (60%) than the group 1 (31.3%). Coronary involvement was observed in 23 patients (29.8%) including 17 patients who had coronary dilation and 6 patients with coronary aneurysm. Conclusion:Coronary artery abnormalities in the group 2 (48.1%) occurred significantly more than the group 1 (20%).
Mucocutaneous Lymph Node Syndrome/ diagnosis ; pathology ; Child

Background: Kawasaki is an acute fever disease with systematic vein infection and often seen in children.Objectives:This study aims to determine features and risk factors of coronary artery lesion (CAL) in Kawasaki disease in children. Subjects and method:A descriptive, prospective study was conducted on 83 patients diagnosed with Kawasaki disease whom treated at National Hospital for Pediatric from January 2005 to March 2007. They were divided into 2 groups: with and without CAL. All data from clinical characteristics, laboratory and echocardiography were analyzed to evaluate the differences between 2 groups. Univariate and multivariate analysis were used. Results: Among 83 patients diagnosed with Kawasaki disease, 27 patients (32.5%) was found with CAL. 24 patients (88.9%) had both right and left coronary artery abnormalities. The CAL in left anterior descending (LAD) and in left circumflex coronary artery (LCX) was 55.6% and 25.9% respectively. Risk level II: 7 patients (25.9%). Risk level III: 14 patients (51.9%) and risk level IV: 6 patients (22.2%). 14 patients (51.9%) with CAL were resolved at 6th month of the illness. Independent risk factors of CAL in acute stage included age under 12 months (OR = 3.97, p<0.05). IVIG treatment was within the first 10 day of the illness (OR=0.25, p<0.05). Non - responsiveness to \u03b3globulin therapy (OR=7.69, p<0.01). CRP before starting initial treatment above 90mg/1 (OR = 12.81, p<0.05). Platelets before starting \u03b3 globulin therapy ~ 557 000/ mm3 with OR=4.73 and p<0.05. Conclusion:Early detection and treatment were necessary in order to decrease CAL in patients with Kawasaki disease.
Mucocutaneous Lymph Node Syndrome/ diagnosis ; pathology ; Coronary Vessels/ pathology ; Child

Mucocutaneous Lymph Node Syndrome; disease; child; early diagnosis From July 2000 to Dec 2002, at HCM city Children Hospital N01, 17 patients aged 4 months to 4 years with Kawasaki disease were treated. All patients had had at least 5 days of fever and 4-5 associated symptoms of Kawasaki disease. Fever was treated with aspirine and gammaglobuline inravenously. Patients who began to treat since 7th day or sooner will get shorter duration of fever, reduce coronary dilation and early discharged from hospital
Mucocutaneous Lymph Node Syndrome ; disease ; child ; early diagnosis

Acute hydrops of the gallbladder is described in one patient who had mucocutaneous lymph node syndrome. During the course of her illness, acute addominal pain, vomiting and right upper guadrant tenderness were developed. Diagnosis was readily made with ultrasonography, and the patient was followed with this te-chnique. We managed her conventionally without surgical intervention. The galbladder returned to normal size within about 3 weeks. Related literatures are briefly reviewed.
Diagnosis* ; Edema* ; Gallbladder* ; Humans ; Mucocutaneous Lymph Node Syndrome* ; Ultrasonography ; Vomiting

Fever ; Humans ; Infant ; Infant, Newborn ; Mucocutaneous Lymph Node Syndrome/diagnosis*

Evidence-Based Medicine ; Humans ; Mucocutaneous Lymph Node Syndrome ; diagnosis ; therapy

We try to discuss the relationship between burn and Kawasaki disease (KD), and to study the diagnosis and treatment of KD in burn children. The medical records of one burn child with KD from our pediatric ward together with those of 5 burn children with KD retrieved from foreign literature were analyzed. The clinical features of KD, including bilateral nonexudative conjunctivitis, erythema of the lips and oral mucosa, skin rash, cervical lymphadenopathy, changes in the distal part of extremities, were enrolled in the study. Six patients were male and younger than 5 years old, with 2 suffering from mild burn, 2 with moderate burn, and 2 with severe burn. Two days after second degree burn, all burn children had fever and skin rash with 4 or 5 clinical symptoms and signs of KD. Among them, coronary artery dilatation was found in 1 case as detected by echocardiography, positive wound culture was found in 2 cases, negative blood culture was found in 6 cases. All patients were given high-dose gamma globulin or (and) aspirin within 10 days after the first fever, followed by control and amelioration of the disease. We conclude that the pathogenesis of KD may be related with burn wound and reabsorption of edema. KD may be suspected in burn children younger than 5 years when they had fever and skin rash at the same time.
Burns ; complications ; diagnosis ; therapy ; Child, Preschool ; Humans ; Male ; Mucocutaneous Lymph Node Syndrome ; diagnosis ; etiology ; therapy