Squamous cell carcinoma(SCC) is a recognized late complication of chronic discoid lupus erythematosus(CDLE). There are many case reports of SCC in white patients with chronic DLE. However, it is uncommon in blacks and Asians. The etiology of squamous cell carcinoma is multifactorial. The predisposing factors for the development of SCC in these patients include actinic keratosis, Bowen's disease, burn scars, arsenic keratosis, and chronic discoid lupus erythematosus. Of these causes, SCC developing in the lesions of CDLE is very rare. We report a patient who has been evaluated for ten years with a diagnosis of discoid lupus erythematosus and has squamous cell carcinoma.
African Continental Ancestry Group ; Arsenic ; Asian Continental Ancestry Group ; Bowen's Disease ; Burns ; Carcinoma, Squamous Cell* ; Causality ; Cicatrix ; Diagnosis ; Humans ; Keratosis ; Keratosis, Actinic ; Lupus Erythematosus, Discoid*

No abstract available.
Diagnosis* ; Polycystic Kidney Diseases*

Bleomycin, an antitumor antibiotic, has several dose-related skin toxicities, including hyperpigmentation, sclerosis, gangrenes, nail changes, and erythema in certain selected skin sites. A case of hyperpigmentation in a linear pattern due to in tavenous injection of bleomycin in a 37-year-old man with squamous cell carcinoma at nasopharynx is described. After 9 months since bleomycin chemotherapy started, dark brownish colored linear hyperpigmentation developed along veins of the skin of both arms.
Adult ; Arm ; Bleomycin* ; Carcinoma, Squamous Cell ; Drug Therapy ; Erythema ; Gangrene ; Humans ; Hyperpigmentation* ; Nasopharynx ; Sclerosis ; Skin ; Veins

A 30-year-old man presented with several intensely prurutic erythematous serpiginous thread-like skin lesions which began as a small papule on the upper back 2 weeks prior to his visit and was migrating to the lower back and buttock area. The laboratory examination showed non-specific findings. Histopathologic examination revealed a pustular burrow containing numerous eosinophils in the epidermis. In the dermis, there was a diffuse and occasionally dense perivascular inflammatory cell inflammation consisting of eosinophils and some lymphocytes. The patient was treated with oral albendazole, antihistamine and topical corticosteroid for 2 weeks without recurrence for 6 months up to now. Multiple histologic sections were made without success in demonstrating parasitic tissue in the epidermis, however, the clinical and histopathologic features were consistent with cutaneous larva migrans.
Adult ; Albendazole ; Buttocks ; Dermis ; Eosinophils ; Epidermis ; Humans ; Inflammation ; Larva Migrans* ; Lymphocytes ; Recurrence ; Skin

Kerion celsi is an inflammatory type of tinea capitis and presents an inflammatory, boggy mass studded with broken hairs, oozing purulent material from follicular orifices. But it occurs usually in children and rarely in normal, healthy adults. We present an unusual case of kerion celsi caused by M. canis in a 69-year-old woman.
Adult* ; Aged ; Child ; Female ; Hair ; Humans ; Microsporum* ; Tinea Capitis*

Subungual exostosis is an uncommon benign tumor of cartilaginous bone arsing adjacent to the distal phalanx of a digit. It is usually a solitary lesion that develops most often in substance of the great toe and less frequently in other toes. The rare presentation of subungual exostosis in a finger usually stimulates an extensive differential diagnosis. We present a case of subungual exostosis of the finger in a 54-year-old female. Roentgenographic findings showed stick-like calcified density on the tip of the distal phalanx of the left 5th finger. Histopathologic findings showed enchondral bone structure and surroundung cartilaginous tissues in the dermis. At 6-month follow-up, the result was excellent, with no sign of recurrence.
Dermis ; Diagnosis, Differential ; Exostoses* ; Female ; Fingers* ; Follow-Up Studies ; Humans ; Middle Aged ; Recurrence ; Toes

Microsporum canis is one of the zoophiles and pets(especially dogs and cats) play a role as a source of this organism. M. canis is most likely transmitted by contact of these animal hosts with humans. We report on 16 foreigners who are infected with M. canis transmitted from a show tiger. Fourteen of the patients had directly contact with a show tiger on occasion. Patients showed typical tinea corporis lesions on the extremities, and the tiger showed hairless patches on the abdomen. The culture and microscopic findings from patients' lesions revealed M. canis as the causative fungus.
Abdomen ; Animals ; Dogs ; Emigrants and Immigrants ; Extremities ; Fungi ; Humans ; Microsporum* ; Tigers* ; Tinea

We report a case of type IIb hyperlipoproteinemia associated with xanthoma tuberosum, xanthoma planum and xanthoma striatum. Serum lipoprotein electrophoresis showed increased beta fraction and pre-beta fraction, suggesting type IIb hyperlipoproteinemia.
Electrophoresis ; Hyperlipoproteinemias* ; Lipoproteins ; Temazepam* ; Xanthomatosis*

BACKGROUND: To clarify the clinicoradiological correlation and prognosis of acute ischemic stroke involving para-median territory of pons. METHODS: We studied 37 patients with first-ever ischemic stroke involving paramedian terri-tory of pons and divided them based on the shape and level of lesion shown in their MRI. The clinical features, MRI findings, and prognosis were assessed. RESULTS: The paramedian infarctions extending to the basal surface were found in 28 patients (76%), and small infarctions separated from the basal surface were found in 9 patients (24%). In patients with infarction extending to the basal surface, 23 patients (82%) had progressive or fluctuating onset, whereas all patients with small infarction separated from the basal surface had non-progressive onset. In the group with upper pon-tine lesion (14 patients), dysarthria-clumsy hand syndrome was found in 4 patients, ataxic hemiparesis (AH) in 3, pure motor hemiparesis (PMH) in 2, and pure sensory stroke in 1. In the group with middle and lower pontine lesion (22 patients), PMH was found in 9, AH in 3, and sensory motor stroke in 2. The mean Modified Rankin Disability Scale scores on admission and after follow-up (mean 29 months) of the group with upper pontine lesion were 2.36 +/-0.50 and 1 . 0 0 +/-0.55, those with mid-lower pontine lesions, 3.48 +/-0.51 and 1.17 +/-0.49 (P<0.01 and P>0.05 respectively). CONCLUSIONS: Paramedian pontine infarction extending to the basal surface usually presents with progressive onset. Paramedian pontine infarction most often produces classic lacune syndrome of which PMH is the most common. In our study, patients with mid-lower paramedian pontine infarction had more severe initial neurological deficits than those with upper paramedian pontine infarction. However, a late outcome was found to be favorable in both groups.
Follow-Up Studies ; Hand ; Humans ; Infarction* ; Magnetic Resonance Imaging ; Paresis ; Pons ; Prognosis* ; Stroke

We describe an 11-year-old male who developed recurrent pyogenic granuloma with satellitosis in the scapular region after surgical excision of a solitary pyogenic granuloma. This is a well-recognized but rare event. Histologic findings showed many newly formed capillaries that had prominent endothelial cells, and varying degrees of dilation without appearance of epidermal collarette sign. We report a case that the satellite lesions were removed by carbon-dioxide laser excision.
Capillaries ; Child ; Endothelial Cells ; Granuloma, Pyogenic* ; Humans ; Male