salivary gland tumors. Pleomorphic adenoma accounts for 60% of all parotid gland tumors, 50% of submandibular gland tumors, and only 25% of sublingual gland neoplasms. Fifty percent of all oral minor gland tumors are pleomorphic adenomas of which 55% arise in the palate, 25% in the lip, 10% in the buccal mucosa, and 10% from all other oral and oropharyngeal sites. The presence of tumors within the parapharyngeal space is rare. Some investigators have reported pleomorphic adenomas originating in the deep lobe of the parotid gland advancing to involve this region, as well as primary pleomorphic adenomas of nonparotid origin. We present a case report of pleomorphic adenoma in the parapharyngeal space with literature review. The tumor was completely removed under general anesthesia via submandibular incision with the division of mandible.]]>
Adenoma, Pleomorphic ; Anesthesia, General ; Humans ; Lip ; Mandible ; Mouth Mucosa ; Palate ; Parotid Gland ; Research Personnel ; Salivary Glands ; Sublingual Gland Neoplasms ; Submandibular Gland

Papillary cystadenocarcinoma originated from salivary gland is a lower grade neoplasm that rises most commonly in major salivary glands, although involvement of lip, palate, buccal mucosa and tongue has also been described. Papillary cystadenocarcinoma was first defined in 1991 by WHO. Until then, it was classified as an atypical type of adenocarcinoma. We experienced a case of papillary cystadenocarcinoma of the submandibular gland, so we report this case with a review of the literature.
Adenocarcinoma ; Cystadenocarcinoma, Papillary* ; Lip ; Mouth Mucosa ; Palate ; Salivary Glands ; Submandibular Gland Neoplasms ; Submandibular Gland* ; Tongue

PURPOSE: The aim of this study is to develop a salivation stimulation method and to verify the effect of a salivation stimulation method on xerostomia in colon cancer patients after surgery. METHODS: This study targeted 21 in the experimental group and 22 in the control group, who were diagnosed with colon cancer and underwent surgery at A university hospital. The salivation stimulation method consists of tongue movement for stimulating minor salivary glands in mouth and a parotid gland and submandibular gland massage with hands. The method was applied four times a day for 2 days the next day after surgery. RESULTS: On the first postoperative day, the experimental group showed a significantly larger amount of salivation than the control group (p=.010). On the second postoperative day, the experimental group showed a significantly larger amount of salivation than the control group (p<.001). On the first postoperative day, the subjective xerostomia scores in the experimental group and control group were not statistically significant (p=.165). On the second postoperative day, the experimental group showed a significantly lower subjective xerostomia score than the control group (p=.001). CONCLUSION: It is considered that providing cancer patients with this salivation stimulation method after surgery would reduce discomfort caused by xerostomia.
Colon* ; Colonic Neoplasms* ; Hand ; Humans ; Massage ; Methods* ; Mouth ; Parotid Gland ; Salivary Glands, Minor ; Salivation* ; Submandibular Gland ; Tongue ; Xerostomia*

INTRODUCTION: The objective of this research was to determine the incidence of oral cancer in Korea. MATERIALS AND METHODS: The classifications of oral and maxillofacial cancer (OMFC) that we used are based on possible locations of OMFC: lip, tongue, mouth, salivary glands, tonsil, oropharynx, nasopharynx, hypopharynx, pharynx unspecified, and nose, sinuses. RESULTS: 1) There were 2,848 OMFC cases, accounting for 1.6% of all cancers. The male to female ratio was 2.72:1. 2) The estimated crude rates (CRs) were 5.7 overall, 8.4 for males, and 3.1 for females. The age-standardized incidence rates (ASRs) were 4.6 overall, 7.3 for males and 2.3 for females. 3) The incidence of mouth cancer was highest. The mouth and salivary glands were the most frequent sites for cancer among males and females, respectively. 4) Patients who were 40 years or older accounted for 91% of OMFC cases, with the highest proportion of cases in the 60-69 year-old age group for both sexes. 5) Tongue cancer was the most prevalent OMFC overall. Nasopharyngeal cancer was highest among males, and salivary gland cancer was highest among females. 6) From 2004 to 2008, the relative 5-year survival rate of OMFC patients was 57.5%. There was a trend of increasing survival among OMFC patients during the study period. The survival rate for females (69.3%) was much higher than that for males (53.1%). CONCLUSION: Social and personal efforts should be required to increase the survival rates of OMFC patients and Korean national cancer management policy should establish new measures for economic and social management and support.
Accounting ; Female ; Humans ; Hypopharynx ; Incidence ; Korea ; Lip ; Male ; Mouth ; Mouth Neoplasms ; Nasopharyngeal Neoplasms ; Nasopharynx ; Nose ; Oropharynx ; Palatine Tonsil ; Pharynx ; Salivary Gland Neoplasms ; Salivary Glands ; Survival Rate ; Tongue ; Tongue Neoplasms

As an uncommon, malignant salivary gland tumor with female predominance, hyalinizing clear cell carcinoma (HCCC) is regarded as an indolent tumor. The diagnosis of this rare tumor is challenging, and it depends on microscopic and immunohistochemical (IHC) studies. Although it is regarded as an indolent tumor, there are reports of unconventional forms with aggressive clinical courses. We report an atypical case of this rare tumor, HCCC, in a male patient who had a relatively large-sized mass (3.8x3.0 cm) on the right mouth floor with ipsilateral neck node metastasis. The clinical, radiological, pathological, and IHC features together with the clinical course are described.
Adenocarcinoma ; Diagnosis ; Female ; Head and Neck Neoplasms ; Humans ; Hyalin* ; Male ; Mouth Floor ; Neck ; Neoplasm Metastasis ; Salivary Glands ; Sublingual Gland

Salivary duct carcinoma is a distinctive salivary gland neoplasm, morphologically characterized by intraductal and infiltrating components. It is an uncommon malignant tumor that occurs in the major salivary glands and its biological behaviour is highly aggressive. Therefore, a salivary duct carcinoma is regarded as a high-grade malignancy. We experienced two cases of salivary duct carcinoma in parotid gland and submandibular gland. The clinicopathologic features of these tumors are presented with a review of literature.
Parotid Gland ; Salivary Ducts* ; Salivary Gland Neoplasms ; Salivary Glands ; Submandibular Gland

Metastasizing pleomorphic adenomas without histological evidence of malignancy have rarely been reported. A case of 30-year-old woman with a mass which showed a benign pleomorphic adenoma appearanced histologically in the left submandibular gland and right supercollarbone respectively was described. Eight years ago, the patient suffered from pleomorphic adenoma of the left submandibular gland. It revealed histopathologic features consistent with the recurrent and metastasizing tumor. The clinic pathological features, possible mechanism and prevention approach of metastasizing pleomorphic adenoma were discussed based on previously reports in the literature.
Adenoma, Pleomorphic ; Female ; Humans ; Parotid Neoplasms ; Salivary Gland Neoplasms ; Submandibular Gland

BACKGROUND: Core needle biopsy is a relatively new technique used to diagnose salivary gland lesions, and its role in comparison with fine needle aspiration cytology needs to be refined. METHODS: We compared the results of 228 ultrasound-guided core needle biopsy and 371 fine needle aspiration procedures performed on major salivary gland tumors with their postoperative histological diagnoses. RESULTS: Core needle biopsy resulted in significantly higher sensitivity and more accurate tumor subtyping, especially for malignant tumors, than fine needle aspiration. No patient developed major complications after core needle biopsy. CONCLUSIONS: We recommend ultrasoundguided core needle biopsy as the primary diagnostic tool for the preoperative evaluation of patients with salivary gland lesions, especially when malignancy is suspected.
Biopsy, Fine-Needle* ; Biopsy, Large-Core Needle* ; Diagnosis ; Humans ; Parotid Gland ; Salivary Gland Neoplasms ; Salivary Glands* ; Submandibular Gland

Sialolipoma, a rare tumor of the salivary gland, is a recently described variant of salivary gland lipoma. Oncocytic sialolipoma was first described by Pusiol et al. in 2009. We report the case of an oncocytic sialolipoma of the submandibular gland in a 43-year-old female. Excision of the tumor was performed with preservation of the submandibular gland. The tumor had a thin, fibrous capsule and consisted of abundant adipose tissue, an oncocytic nodule, and scattered normal glandular structures surrounded by adipose tissue. Four cases of sialolipoma of the submandibular gland, including the present case, were reviewed. All 4 tumors were developed on the right submandibular glands, with a composition of adipose tissue as high as that of sialolipoma of the parotid gland; in contrast to previous reports, three cases were in females. As newly described tumor type, care should be taken to distinguish oncocytic sialolipoma from other salivary gland neoplasms such as simple lipoma, pleomorphic adenoma, or oncocytoma.
Adenoma ; Adenoma, Oxyphilic ; Adipose Tissue ; Adult ; Female ; Humans ; Lipoma ; Parotid Gland ; Salivary Gland Neoplasms ; Salivary Glands ; Submandibular Gland*

Sebaceous carcinoma of the salivary gland is an extremely unordinary malignancy occurring mainly in the parotid gland. Sebaceous carcinoma arising in the submandibular gland is exceptional and only three cases have been reported in the literature. We herein present a unique case of sebaceous carcinoma of the submandibular gland, the first to be reported in literature in South Korea. An 85-year-old man visited our hospital complaining of a progressively enlarging submandibular mass with tenderness and ipsilateral facial palsy. We performed a wide excision of the mass with superficial parotidectomy and modified neck dissection. Microscopic and immunohistochemical examinations demonstrated sebaceous carcinoma of low grade differentiation. Further adjuvant radiotherapy was rejected and the patient was followed up for five months. The optimal treatment of sebaceous carcinoma of the salivary gland is still not established due to the rarity of the disease. When more cases are reported, the clinicopathologic characteristics will be better understood.
Aged, 80 and over ; Facial Paralysis ; Humans ; Korea ; Neck Dissection ; Parotid Gland ; Radiotherapy, Adjuvant ; Salivary Gland Neoplasms ; Salivary Glands ; Submandibular Gland Neoplasms ; Submandibular Gland*