1.Retrospective Analysis of the Serovars and Antibiogram of Vibrio cholerae Isolates of the 2017 Ilorin Cholera Outbreak, Nigeria
Dele Ohinoyi AMADU ; Idris Nasir ABDULLAHI ; Ezekiel SEIBU ; Abayomi FADEYI ; Khadeejah KAMALDEEN ; Aliu Ajibola AKANBI ; Chukwudi Crescent OKWUME ; Motunrayo Bukola AMADU ; Charles NWABUISI
Infection and Chemotherapy 2021;53(2):368-373
In this retrospective study, we determined the incidence, serovars, and antibiogram of Vibrio cholerae isolated from 102 clinical stool samples collected from rice water diarrheic patients during an outbreak (May - July 2017) in Ilorin metropolis, Nigeria. The culture positive rate of the V. cholerae isolates was 41.2%, with 41 and 1 isolates from O1 (Inaba) and non-O1/O139 serogroups, respectively. The isolates were the most susceptible to ciprofloxacin (76.2%) followed by amoxicillin-clavulanate (71.4%). However, all isolates were resistant to ampicillin and tetracycline. In conclusion, V. cholerae O1 was the predominant circulating serogroup exhibiting multi-drug resistance during the outbreak.
2.Retrospective Analysis of the Serovars and Antibiogram of Vibrio cholerae Isolates of the 2017 Ilorin Cholera Outbreak, Nigeria
Dele Ohinoyi AMADU ; Idris Nasir ABDULLAHI ; Ezekiel SEIBU ; Abayomi FADEYI ; Khadeejah KAMALDEEN ; Aliu Ajibola AKANBI ; Chukwudi Crescent OKWUME ; Motunrayo Bukola AMADU ; Charles NWABUISI
Infection and Chemotherapy 2021;53(2):368-373
In this retrospective study, we determined the incidence, serovars, and antibiogram of Vibrio cholerae isolated from 102 clinical stool samples collected from rice water diarrheic patients during an outbreak (May - July 2017) in Ilorin metropolis, Nigeria. The culture positive rate of the V. cholerae isolates was 41.2%, with 41 and 1 isolates from O1 (Inaba) and non-O1/O139 serogroups, respectively. The isolates were the most susceptible to ciprofloxacin (76.2%) followed by amoxicillin-clavulanate (71.4%). However, all isolates were resistant to ampicillin and tetracycline. In conclusion, V. cholerae O1 was the predominant circulating serogroup exhibiting multi-drug resistance during the outbreak.