No abstract available.
Lung* ; Thorax*

Decreased tear production may occur with aging and dry eye is a common ocular disorder in the aged population, especially for postmenopausal women. The thickness of the lacrimal gland was measured by the orbital computed tomography to identify morphologic changes of the lacrimal gland in relation to age and sex. The measurements of thickness of the lacrimal glands of 238 eyes by orbital computed tomography showed a statistically significant decrease in relation to age in females, but no significant change in males. The change of the lacrimal gland in relation to aged population, especially for postmenopausal women, showed a statistically significant. I suggest that the result of the study is cause of dry eye for postmenopausal women.
Aging* ; Female ; Humans ; Lacrimal Apparatus* ; Male ; Orbit*

Extramammary Paget disease (EMPD) is a rare cutaneous neoplasm. Perianal Paget disease (PPD) is a subset of EMPD manifesting perianal lesions. Two cases of PPD in Severance Hospital are described in this article. A 65-year-old female and 78-year-old male patients visited our institution because of an unhealed perianal skin lesion despite treatment for a long period with topical agents. PPD was diagnosed by skin biopsies in both cases, and the patients underwent surgical treatment. Clinical manifestations, preoperative work-ups, and surgical treatments including different reconstruction methods are described in detail. As only sporadic PPD cases have been reported and no standard treatment has been established, we hope that our experience could contribute to improving the diagnosis and treatment of PPD patients.
Aged ; Biopsy ; Diagnosis ; Female ; Hope ; Humans ; Male ; Paget Disease, Extramammary ; Skin

Extramammary Paget disease (EMPD) is a rare cutaneous neoplasm. Perianal Paget disease (PPD) is a subset of EMPD manifesting perianal lesions. Two cases of PPD in Severance Hospital are described in this article. A 65-year-old female and 78-year-old male patients visited our institution because of an unhealed perianal skin lesion despite treatment for a long period with topical agents. PPD was diagnosed by skin biopsies in both cases, and the patients underwent surgical treatment. Clinical manifestations, preoperative work-ups, and surgical treatments including different reconstruction methods are described in detail. As only sporadic PPD cases have been reported and no standard treatment has been established, we hope that our experience could contribute to improving the diagnosis and treatment of PPD patients.
Aged ; Biopsy ; Diagnosis ; Female ; Hope ; Humans ; Male ; Paget Disease, Extramammary ; Skin