Rickets is a syndrome, characterised pathophysiologically by a failure of normal mineralization of bone and epiphyseal cartilage and clinically by skeletal deformity in growing children. The four principal causes of rickets are; vitamin D deficency, renal tubular insufficiency, chronic renal insufficiency, and hypophosphatasia. Of these, vitamin D resistant rickets may result from primary defect in function of the renal tubular reabsorption for phosphorus, later accompsnied with secondary hyperparathyroidism. We experiened a rare case of hypophosphstemic vitamin D resistant rickets accompanied with secondary hyperparathyroidism in adolescence.
Adolescent ; Child ; Congenital Abnormalities ; Familial Hypophosphatemic Rickets ; Growth Plate ; Humans ; Hyperparathyroidism, Secondary ; Hypophosphatasia ; Miners ; Phosphorus ; Renal Insufficiency, Chronic ; Rickets ; Vitamin D ; Vitamins

It has been known that the obesity is one of the predisposing factors of the primary degenerative arthritis of knee. And nowadays, it seems that the number of obese person increases gradually in Korea. The authors studied 50 cases of the degenerative arthritis of knee clinically and statistically, compared with 50 cases of the control group, in the Department of Orthopedic Surgery, Seoul National University Hoispital from Jan. to Aug. 1981. The results were as follows: l. Among the degenerative arthritis of knee, the ratio of male: female was 1:9, and the age group with the highest frequency was the 5th. decade (48%). 2. Thirty-two cases (64%) was obese in the degenerative arthritis group, and 7 cases (14%) was obese in the control group. 3. The incidence of obesity in the degenerative arthritis group was 13.5 times higher than that in the control group, and it was highly significant statistically.
Causality ; Female ; Humans ; Incidence ; Knee ; Korea ; Male ; Obesity ; Orthopedics ; Osteoarthritis ; Seoul

PURPOSE: Variable modalities, with more comfortable and less incidence of post-operative complications over TURP, have been used for the treatment of benign prostatic hyperplasia(BPH) with bladder outlet obstruction. Recently, we performed Interstitial Laser Coagulation(ILC) with the 830nm diode laser, which is considered as a method of minimally invasive treatments for BPH, to assess the efficacy and safety of the device, and to evaluate its capability of replacing TURP for managing BPH. MATERIALS AND METHODS: We analysed 16 patients, who had suffered from symptomatic BPH, treated with ILC using diode laser retrospectively from April 1996 to January 1997. Mean age of the patients was 71.7(52-84) years old and mean size of prostates before the treatments was 52.2(26.8-100.7)gm. Treatment outcome was estimated by comparing IPSS, QOL, Qmax, Qave and residual urine before the operations with them of first and second month after the operations. Post-operative transrectal ultrasonography was able to several cooperative cases and they were compared with them of pre-operative volumes, too, although it was unavailable to evaluate statistically. RESULTS: The operation were performed under epidural or spinal anesthesia with average time of 62 minutes and with 10 days of post-operative catheterization. IPSS reduced from 22.25(+/-4.82), mean value before the operation, to 11.00(+/-5.58) and 5.00(+/-3.10) at first and second month after ILC. QOL was gradually decreased from 4.44(+/-0.51) to 2.31(+/-1.20) and 1.19(+/-0.91), too. In terms of Qmax, mean was 12.29(+/-5.55)ml/sec before the operation and it was increased to 15.94(+/-7.38)ml/sec and 20.75(+/-8.48)ml/sec. Average flow rate was also increased from 6.98(+/-2.05)ml/sec to 10.38(+/-3.72)ml/sec and 14.93(+/-4.37)ml/sec. Significant reduction was observed in residual urine volume from 98.13(+/-91.72)ml to 33.19(+/-36.58)ml and 9.56(+/-11.24)ml respectively. Minimal hematuria and mild bladder irritations were common symptoms after the procedure, and possible significant complications as like anemia, electrolyte imbalance(post-TUR syndrome), epididymoorchitis, erectile dysfunction, urethral stricture, retrograde ejaculation had not found in our experience, but 1 patient was retreated with TURP because of continued bladder outlet obstruction. CONCLUSIONS: Our initial results with ILC showed that it is a relatively simple and minimally invasive method with minimal occurrence of bleeding and no electrolyte imbalance. We concluded that ILC is a safe and efficacious treatment modality, and it can be used even for elder patients with co-morbidity illness as well as patients with too large prostate to perform TURP.
Anemia ; Anesthesia, Spinal ; Catheterization ; Catheters ; Ejaculation ; Erectile Dysfunction ; Hematuria ; Hemorrhage ; Humans ; Incidence ; Lasers, Semiconductor ; Male ; Prostate ; Prostatic Hyperplasia* ; Retrospective Studies ; Transurethral Resection of Prostate ; Treatment Outcome ; Ultrasonography ; Urethral Stricture ; Urinary Bladder ; Urinary Bladder Neck Obstruction

In order to investigate the occurrence characteristics of cancer in terms of industry in Kwangju-Chonnam area, medical utilization records of industrial medical insurance corporations during the period of 1987 to 1988 were reviewed for the identification of neoplastic disease. The cases obtained from the medical records were followed up for the verification and to get additional information. Standardized incidence data were compared by occupational characteristics. Multiple logistic regression analysis was applied to analyze the difference of incidence or distribution of cancer as a whole or of some selected cancer. Total cases of cancer identified were 242 during the study period. Annual incidence rate was calculated as 123.1 per 100,000 person. The frequent types of cancer were cancers of stomach, liver, lung, colon and rectum, bladder and lymphoma in descending order. Employees of mine and other sand handling industries showed significantly higher risks for cancer of stomach and cancer as a whole. Employees of the transportation industry showed the higher risk for cancer of liver. Workers in small-sized industry (< or = 100) had a higher risk for cancer than who in large-sized industry (>100). These findings suggested the effect of occupational environmental exposure to cancer development.
Colon ; Environmental Exposure ; Humans ; Incidence ; Insurance* ; Liver ; Liver Neoplasms ; Logistic Models ; Lung ; Lymphoma ; Medical Records ; Occupations ; Rectum ; Silicon Dioxide ; Stomach ; Stomach Neoplasms ; Transportation ; Urinary Bladder

Infectious process involves infrequently the posterior compartment of the vertebra. Three cases of such condition are experienced at the Dept. of Orthopedic Surgery, Seoul National University during the period of August 1962 to June 1971 Two of three cases were from pyogenic infection invoIving the spinous process of third and fourth lumbar vertebra respectively, one of which was complicated by formation of paraspinal abscess and both were treated with total laminectomy of the involved vertebrae. Thee third case was tuberculosis on the transverse process of first thoracic vertebra which was accompanied by irritating sign of left ulnar nerve, and was treated with transversectomy and partial laminectomy. Excellent results were obtained without recurrence and no deformity nor instability of the spine developed postoperativeIy.
Abscess ; Congenital Abnormalities ; Laminectomy ; Orthopedics ; Recurrence ; Seoul ; Spine ; Tuberculosis ; Ulnar Nerve

We present one case report of anterior urethral diverticulum in a male with giant calculi. The patient was a 56-year-old male with the complaints of base-ball sized palpable scrotal mass and post-void dribbling for 15-16 years. The diverticulum was filled with multiple whitish-yellow stones. The largest one was 8X7X6cm in size.
Calculi* ; Diverticulum* ; Humans ; Male* ; Middle Aged

Foreign bodies in the genitourinary tract are relatively common, and almost of them are discovered within the bladder. We had experienced a patient and report herein, who had a plastic tube in the bladder, introduced through urethra during masturbation. The size of the tube was 110cm in length and 0.5cm in diameter, and it was easily diagnosed by history, symptoms, simple KUB, cystoscopy, and was removed by foreign body forceps under the cystoscopy.
Cystoscopy ; Foreign Bodies* ; Humans ; Masturbation ; Plastics ; Surgical Instruments ; Urethra ; Urinary Bladder*

The authors experience 3 cases of angiographically occult vascular malformation(AVOM) of the brain during the last 3 months in 1990. All cases were diagnosis of either operative or pathological finding and were associated with intracerebral hemorrhage. The authors recommend that surgery should be considered even to those angiographically negative intracerebral hemorrhage cases, once clinical features are highly suggestive of AOVM. Surgery can be an effective and define therapy for these entities, which are prone to cause recurrent hemorrhage and persistent neural deficits.
Brain* ; Cerebral Hemorrhage ; Diagnosis ; Hemorrhage ; Magnetic Resonance Imaging ; Vascular Malformations*

23 eyes of 23 patients who underwent conventional vitreoretinal surgery with high specific gravity perfluorocarbon liquid, perfluorophenanthrene, for complicated retinal detachment were evaluated retrospectively. Preoperative vitreoretinal findings showed grade C2 PVR in 4 eyes and C3 in 1 eye and C4 in 10 eyes and C5 in 8 eyes. As a result, 17 eyes(74%) showed anatomical success, completely reattached in 15 eyes, partially reattached in 2 eyes, and 12 eyes(52%) showed functional success (corrected visual acuity 5/200 or better). Follow-up period was over 6 months in all cases. Postoperative complications includes keratopathy in 6 eyes, hypotony in 5 eyes, cataract in 2 eyes, transient vitreous hemorrhage in 1 eye, acute increased IOP in 1 eye, posterior synechiae in 1 eye, cystoid macular edema in 1 eye, and pupillary membrane in 1 eye. Consequently, perfluorophenanthrene can be used beneficially in yield of surgical field and mechanical stabilization of retina in complicated retinal detachment surgery.
Cataract ; Follow-Up Studies ; Humans ; Macular Edema ; Membranes ; Postoperative Complications ; Retina ; Retinal Detachment* ; Retinaldehyde* ; Retrospective Studies ; Specific Gravity ; Visual Acuity ; Vitreoretinal Surgery ; Vitreous Hemorrhage

No abstract available.
Vascular System Injuries