No abstract available.
Bipolar Disorder*

No abstract available.
Child* ; Human Growth Hormone ; Humans ; Kidney Failure, Chronic*

PURPOSE: To evaluate the diagnostic accuracy of T-tube cholangiography(TTC), selective cholangiography (SC) and noncontrast CT(NCT) in the evaluation of intrahepatic stone disease. MATERIALS AND METHODS: We retrospectively analyzed the radiological findings of these methods in thirty patients with intrahepatic stones proved by percutaneous removal. Findings of each procedure were reviewed and correlated with findings of stone removal procedure. RESULTS: Detection of stones was possible in 87. 0% for TTC, 90. 0% for SC, 96. 7% for NCT(p > 0.05). Selective cholangiography was as good as or superior to 1-I'C in determining the presence and extent of the stones in all patients(p < 0. 01). NCT was better than SC in 9;as good as SC in 18;inferior to SC in 3 patients in determining the extent and location of the stones(p > 0.05). Of 12 patients who had additional findings such as biliary cirrhosis or accompanied cholangiocarcinomas, only NCT could detect the lesions in 11 patients. CONCLUSION: Although there was no statistically significant difference between NCT and SC, one procedure sometimes gave valuable informations for interventional procedure which the other could not. Thus we conclude that both procedures are complementary studies and should be done in all patients who are subjected to biliary intervention.
Cholangiocarcinoma ; Cholangiography* ; Humans ; Liver Cirrhosis, Biliary ; Retrospective Studies

PURPOSE: The purpose of this study is to find helpful MR findings for predicting a naplastic oligodendrogl lomas. MATERIALS AND METHODS: Retrospective analysis of 46 MR images and 37 CT scans was performed for 46 patients with pathologically-proven cerebral oligodendrogliomas. A neuropathologist graded the tumors as one of low-grade (n=16), intermediate-grade (n=l2), or anaplastic oligodendroglioma (n=18). MR imaging features were retrospectively analysed with respect to histologic grading of the tumors. RESULTS: Contrast enhancement was observed always in anaplastic group (17 /17), in a portion of intermediate-grade group (4/10) but not in low-grade group (0/14). Peritumoral edema was observed infrequently in anaplastic group (4/18) or intermediate-grade group (1/12). Cystic changes (25/46) or calcifications on CT Scans (14/37) were not related with histologic grading. Grossly identifiable hemorrhage was rare in this series (2/46). Among the various imaging features, only tumor enhancement and peritumoral edema were statistically significant for trend test (p<0.05). CONCLUSION: When considering the diagnosis of oligodendrogliomas, the presence of contrast enhancement or peritumoral edema is a helpful features suggesting anaplastic oligodendrogliomas.
Diagnosis ; Edema ; Hemorrhage ; Humans ; Loma ; Magnetic Resonance Imaging ; Oligodendroglioma* ; Retrospective Studies ; Tomography, X-Ray Computed

It is important to predict the prognosis of patient with cancer. Well known parameters predicting the prognosis are staged and degree of differentiation. Recently, the prognostic and diagnostic significance of silver-stained nucleolar organizer regions(Ag-NORs) and flow cytometric DNA analysis are introduced. This study aims to detect the diagnostic significance of Ag-NORs in breast lesions, and to correlate the number of Ag-NORs and cellular ploidies in breast carcinoma. In addition, the existence of heterogeneity according to the sample in the same patient is studied Sixty six paraffin blocks(two primary lesions and the two metastatic lymph nodes in 13 patients, and one primary lesion and one metastatic lymph node I 10 patients) of breast carcinoma, 30 paraffin blocks of fibroadenoma and 23 paraffin blocks of normal breast are studied. The numbe of Ag-NORs increase from normal breast(mean 1.45) through fibroadenoma(mean 1.60) to carcinoma(mean 2.43). It was significantly different between each lsions(P<0.0005). The number of Ag-NORs increased in the aneuploidy carcinoma than that in the euploidy one(P<0.05). But, there was difference between the number of Ag-NORs and DNA index according to the sample area in the same patient with carcinoma. In conclusion, the number of Ag-NORs is diagnostically significant in breast lesions and is correlated with cellular ploidies in breast carcinoma. In addition, Ag-NORs and cellular ploidies are heterogenous in the same patient.
Neoplasm Metastasis

No abstract available.

Aspiratian of gastric contents during anesthesia is the most common cause of maternal anesthetic death. Particularly, the parturient is predisposed to the catastrophe of aspiration for many reasons. So, the effect of cimetidine premedication on gastric pH and volume were studied. 120 ASA Class I patients scheduled for elective obstetric and gynecologic surgery were randomly divided into six groups as follows: Class A(n=80) is pregnant women scheduled for elective cesarean section. In the class A, group 1(n=20)(control group) was received no cimetidine premedication, group 2(n=20) was received cimetidine 300 mg p.o. hs. group 3(n=20) was received cimetidine 300 mg p.o. 2hrs before anesthesia, and group 4(n=20) was received cimetidine 200 mg iv 2hrs before anesthesia. Class B (n=40) is 20-40 aged non-pregnant women scheduled for elective surgery. ln the class B, group 5(n=20)(control group) was received no cimetidine premedication and group 6(n=20) was received cimetidine 200 mg iv 2hrs before anesthesia. Immediately following induction of anesthesia, the gastric fluid was obtained by suction on a nasogastric tube and its volume and pH were measured. The results were as follows: 1) When cimetidine is not premedicated, number of patient with a gastric pH less than 2,5 and gastric volume greater than 25 ml was increased in the group 1 compared with group 5. 2) In the class A, there was significant increased gastric pH and decreased gastric volume in the group 2, 3, and 4 compared with group l. 3) In the class B, there was significant increased gastric pH and decreased gastric volume in the group 6 compared with group 5. In conclusion, it would seem that the risk of aspiration pneumonitis can be increased in the pregnant women compared with nonpregnant women. The authors recommend that the incidence of severe aspiration pneumonia can be decreased by cimetidine premedication before general anesthesia even though there is any gastric aspiration.
Anesthesia ; Anesthesia, General ; Cesarean Section* ; Cimetidine* ; Female ; Gynecologic Surgical Procedures ; Humans ; Hydrogen-Ion Concentration* ; Incidence ; Pneumonia ; Pneumonia, Aspiration ; Pregnancy ; Pregnant Women ; Premedication ; Suction

PURPOSE: The authors investigated the ability of cardiac blood pool clearance rates(CBCR) of 99mTc-DiSiDA in the measure merit of functioning hepatocyte mass. MATERIALS AND METHODS: We measured the volume of Iobectomized liver after completion of postoperative scanning with CBCR of 99rnTc-DISIDA in 5 rabbits who the functional hepatic Iobectomy performed by ligation of hepatic artery, portal vein and biliary tracts. Regarding the measurement of CBCR of 99mTc-DISIDA, we set the time which was decreased to the half of the clearance amount of the cardiac radioactivity by hepatic extraction of 99mTc-DISIDA at the point of 50 sec after the renal peak of the radioactivity to prevent confusing with the blood dilution of the radioactivity, that have called DI-K50. RESULTS: The results were followed that the volumes of the functional hepatic Iobectomy in 5 rabbits were 25%, 25%, 41%, 52%, 75% and the residual functioning hepatocyte masses measured by CBCR of 99rnTc-DISIDA were preserved to 75. 1%, 70. 8%, 63. 0%, 52. 2%, 30. 8% respectively. CONCLUSION: we made decision that CBCR of 99rnTc-DISlDA was useful to evaluate the functioning hepatocyte mass.
Biliary Tract ; Hepatic Artery ; Hepatocytes* ; Ligation ; Liver ; Portal Vein ; Rabbits ; Radioactivity ; Technetium Tc 99m Disofenin*

Congenital melanocytic nevi are considered to be precursors of malignant melanoma. Although the risk of malignant melanoma with medium and small congenital melanocytic nevi is uncertain, it is important to notice the possibility of malignant transformation in those lesions. We describe a 62-year-old woman who had had a brown soft verrucous tumor on her right lower back since birth. She first noticed a black nodule in the center of the tumor 5 years before which had ulcerated 3 months prior to presentation without healing. A biopsy specimen revealed malignant melanoma arising from a congenital melanocytic nevus.
Biopsy ; Female ; Humans ; Melanoma* ; Middle Aged ; Nevus, Pigmented* ; Parturition ; Ulcer

CT scans of 21 patients(intrathoracic goiter=7. Castleman disease=6, pulmonary carcinoid tumor=3, parathyroid adenoma=1, thyroid carcinoma=1, paraganglioma=1, benign pleural mesothelioma=1, sclerosing hemangioma=1) with mediastinal tumors that are known to be enhanced with intravenous injection of contrast media, were studied retrospectively to investigate the enhancing capabilities f those tumors and to describe their CT findings. The degree of enhancement was estimated by visual inspection with a grading system. All but one case of cystic parathyroid adenoma showed enhancement on post-contrast scan. The degree of enhancement was not helpful in differentiating these tumors. Characteristic location and pattern of tumor extension were found in cases of intrathoracic goiter, parathyroid adenoma, thyroid carcinoma and paraganglioma. Calcifications were found in intrathoracic goiter(5/7). Castleman disease(2/6). Pulmonary carcinoid(1/3), thyroid carcinoma. Necrotic low-attenuation areas were in intrathoracic goiter(7/7), parathyroid adenoma, thyroid carcinoma and paraganglioma. In conclusion, mediastinal tumors that are known to be enhanced in the literature were enhanced with rare exception, and if we consider the predilection site of those tumors, the scope of differential diagnosis can reasonably be narrowed.
Carcinoid Tumor ; Contrast Media ; Diagnosis, Differential ; Goiter, Substernal ; Injections, Intravenous ; Paraganglioma ; Parathyroid Neoplasms ; Retrospective Studies ; Thyroid Gland ; Thyroid Neoplasms ; Tomography, X-Ray Computed