Benzoyl peroxide has been known to have bacteriostatic activity against Corynebacterium acnes and to have comedolytic action in patients with acne vulgaris. The present study was undertaken to evaluate the therapeutic effect of Renoxal, a 5% benzoyl peroxide lotion, in patients with acne vulgaris. A total of 35 patients entered this study at the Department of Dermatology, Seoul National University Hospital during the five months period from March to July, 1978. All patients were instructed to apply Benoxal on their affected sites once or twice daily; and the number of lesions on three fixed areas were counted before and every week for four weeks after the treatrnent. Two female patients stopped the application due to developrnent of contact dermatitis to Benoxal The results observed in the 33 patients were as follows: 1. The percentage decrease in total number of lesions in four weeks after treatment was 51.1% 2. Closed and open comedones were gradually eliminated; and their numbers were decreased in four weeks after treatment by 45. 8% and 55. 3% respectively. The papules were decreased. by 59. 1 @2 after the first week of treatment, but showed. a transient lag around tbe second week and then marked 61. 5% in four weeks after treatment. 3. Observed side effects included burning sensation,(3 cases), tightness (3 cases), itching sensation (2 cases) and scaling (1 case). All were tolerable without any specific measure or discontinuance of the application. The authors concluded througb this experiment that Benoxal (5% benzoyl peroxide lotion) is a very effective local therapeutic agent in the treatment of acne vulgaris patients.
Acne Vulgaris* ; Benzoyl Peroxide ; Burns ; Dermatitis, Contact ; Dermatology ; Female ; Humans ; Propionibacterium acnes ; Pruritus ; Sensation ; Seoul ; Thiram

Most of the malignant tumors of the pancreas are adenocarcinomas arising from the ductal epithelium. Primary leiomyosarcoma of the pancreas, even though it is the most common sarcoma of the pancreas, is very rare. We present a case of leiomyosarcoma of the pancreas, probably primary, with metastases to the stomach, lymph nodes, and abdominal wall. A 52-year-old woman visited the hospital with vague right upper abdominal pain and weigh loss of 6 kg for 2 months. The radiological and endoscopic examination revealed that she had a large heterogeneous mass, 11 cm in size, in the pancreatic body and tail, a 4 cm-sized mass in the paraaortic area, and a 3 cm-sized polypoid mass in the stomach. Histologically, they were all similar to one another and composed of markedly pleomorphic cells. Immunohistochemical and electron microscopic studies showed definite smooth muscle differentiation of the tumor cells. Two months later, the patient underwent an excision of a new 3 cm mass in the right lower abdominal wall, showing features of well differentiated leiomyosarcoma.
Abdominal Pain ; Abdominal Wall ; Adenocarcinoma ; Epithelium ; Female ; Humans ; Leiomyosarcoma* ; Lymph Nodes ; Middle Aged ; Muscle, Smooth ; Neoplasm Metastasis ; Pancreas* ; Sarcoma ; Stomach

No abstract available.
Acne Vulgaris*

No abstract available.
Prune Belly Syndrome*

No abstract available.
Prune Belly Syndrome*

By implementing epoch-making policies for industrial promotion, the national economy has made a remarkable development. As a result of such economic growth, industrial accidents and occupational diseases have become a serious problem in Korean society. In the presidential order for the execution of the Korean Labor Standard Law, neuritis and other diseases stemming from health impairments due to vibrations in industrial processes are designated to be dealt with as vibration diseases. In the case of vibration disease, industrial accident compensation is not effectively paid. In order to investigate the vibration hazards of rock-drill operation, the authors studied the subjective symptoms and performed physical function tests on a total of 79 persons (vibration exposed group) who used rock-drills, and 39 persons (control group) who did not use rock-drills at anthracite mines. The results of the physical function test were as follows : 1. The right hand was more affected by white finger than the left hand. 2. Independent variables such as duration of rock-drill operation, age, drinking and smoking were identified as statistically significant factors for the occurrence of white finger. 3. In the pain sense threshold, the group with Raynaud's phenomenon showed a statistically higher level than that of the control group. 4. The skin temperature of the group with Raynaud's phenomenon was lower than that of the control group. The recovery time of skin temperature after cooling was delayed compared with the value of the control group.
Accidents, Occupational ; Coal* ; Compensation and Redress ; Drinking ; Economic Development ; Fingers ; Hand ; Humans ; Jurisprudence ; Neuritis ; Occupational Diseases ; Skin Temperature* ; Skin* ; Smoke ; Smoking ; Vibration

PURPOSE: The purpose of this study was to identify the level of knowledge about dementia and to find the related factors in middle-aged adults. METHOD: The research design was a descriptive study by using a constructive self-report questionnaire with 34 items. Data were collected from 397 middle-aged adults using structured questionnaire. Data analysis was done by SPSS/WIN Programs using frequency, range from minimum to maximum, percentage, mean, SD, chi-square-test, t-test, ANOVA, and Duncan's Multiple Range test. RESULTS: The rate of correct answer of middle-aged adults was 68.7%, showing the mid-level of knowledge about dementia. There were significant differences according to age, education, marital status, job, income, information and information sources for dementia in middle-aged adults. CONCLUSION: These results indicate that Korean middle-aged adults need more education and counseling on dementia. Further studies are needed to overcome regionalism in sampling of this study and to develop standard measuring tools for the level of knowledge about dementia.
Adult* ; Counseling ; Dementia* ; Education ; Humans ; Marital Status ; Research Design ; Statistics as Topic ; Surveys and Questionnaires

No abstract available.
Acromegaly* ; Hydroxymethylglutaryl-CoA Reductase Inhibitors*

No absract available.
Diet* ; Humans

We have reported general principles of low vision aid prescription. But, we have not reported near vision aid prescription only. So, we analyse prescriptions of near low vision aid(diagnosis, type, magnification, etc) and present new near low vision aids that patients feels comfortable. We reviewed the clinical records of 100 patients who visited our low vision clinic more than twice and was prescribed near low vision aid for low vision. According to the data analysed, optic nerve atrophy was the most common etiology for low vision. Illuminated hand held magnifier(31.3%), telemicroscope with plus cap(27.7%), aspheric doublet sens(Clear Image II)(24.1%) were low vision aids most commonly used for near vision, but we knew new trend that newly prescribed aids(telemicroscope with plus cap, aspheric doublet lens) were prescribed more than illuminated hand held magnifier. After prescription of the low vision aid, visual acuity improved significantly (p<0.05). We examined contrast sensitivity test to measure the functional acuity and predict the visual prognosis after prescription of low visio aid.In addition,we studied the relationship between reading speed and the degree of contrast sensitivity and we knew that the relationship between degree of contrast sensitivity and reading speed was associated(p<0.05). Majority of patients(89%) were benefited from prescribed low vision aids.
Atrophy ; Audiovisual Aids ; Contrast Sensitivity ; Hand ; Humans ; Optic Nerve ; Prescriptions* ; Prognosis ; Vision, Low*