No abstract available.
Cellulitis* ; Staphylococcus aureus* ; Staphylococcus*

Clinical and bacteriological studies were made on 168 cases of culture proved childhood shigellosis at Wallace Memorial Baptist Hospital in Busan between Aug. 1978 and July 1980. The following results were obtained. 1. Of 168 cases, 99 cases were male and 69 were female, the ratio being 1.4:1. The most frequently affected age group was between one three six years(57.7%) and the youngest was one month old infant(2 cases). 2. The peak incidence was in summer (34.5%), however it occurred throughout the year, even in winter(17.3%). 3. The most frequent symptoms on admission were diarrhea (86.9%), fever(77.4%), vomithing (36.9%), convulsion(38.7%) and abdominal pain(28.6%). 4. WBC count in peripheral blood was variable from leukocytosis to leukopenia and over 5% of band form was seen in 52.4%. 5. Sh. Flexneri was the most frequently isolated strain(86.3%) followed by Sh. Sonnei(6.5%), Sh. Boydii(4.8%) and Sh. Dysenteriae (2.4%). 6. The result of sensitivity test reveales that Oxolinic acid was the most sensitive drug(86.2%) followed by Gentamicin(83.9%) and Cefazolin(80.4%). It also revealed the high prevalence of resistance to Ampicillin(88.0%), Chloramphenicol(92.7%) and Tetracycline (95.6%). 7. 54 isolated shigellae strains were tested for Minimal Inhibitory Concentration in tube dilution method and inhibition zone diameter in single disc test (Rifampin disc 5g/ml). MIC were below 12.5g/ml in 77.7% and below 25g/ml in 90.7% and inhibition zone diameter was over 8mm in 88.7%. 8. Clinical response to antibiotic therapy revealed that clinical improvement was seen within 5 days of therapy in 48.1% of Ampicillin therapy group and 58.1% of Septrin therapy group and within 4 days of therapy in 95.7% of initial Rifampin therapy group and 97.2% of altrnative Rifampin therapy group. 9. Bacteriological response to antibiotic therapy revealed that within 4 days of Ampicillin and Septrin therapy the negative conversion rate was 49.1% and 54.4% respectively. The negative conversion within 3days of Rifampin therapy was observed in 93.4% of initial therapy group and 96.6% of alternative therapy group. 10. There was no untoward reaction of Rifampin during therapy except for the reddish discoloration of urine and stool.
Ampicillin ; Busan ; Diarrhea ; Dysentery, Bacillary* ; Female ; Humans ; Incidence ; Leukocytosis ; Leukopenia ; Male ; Oxolinic Acid ; Prevalence ; Protestantism ; Rifampin* ; Shigella ; Tetracycline ; Trimethoprim, Sulfamethoxazole Drug Combination

BACKGROUND: Recent reports suggest that Epstein-Barr virus (EBV) may play an important role in such a wide spectrum of human neoplasia. Recently, peripheral T cell lymphomas and particularly, angiocentric lymphomas (ACL), increasingly are reported to be associated with EBV.Nasal-type and nasal T/NK cell lymphoma (TNKL) have recently been reported to comprise most of ACLs. The prognosis of these tumors has been extremely poor. OBJECTIVE: The purpose of this study was to investigate EBV association in primary or secondary cutaneous T-cell lymphoproliferative disorders and to identify any prognostic association. METHODS: Thirty six patients with primary or secondary cutaneous T-cell lymphoproliferative (CTCL) disorders were examined to evaluate the presence of Epstein-Barr virus using in situ hybridization for EBV-encoded RNA (EBER). RESULTS: EBER was detected in tumor cells in one third of the total cases (13/36); 4/4 secondary skin lymphoma from nasal TNKL, 8/8 primary cutaneous nasal type TNKLs and 1/5 mycosis fungoides (MF).EBER was not detected in the following disease: 6 cases of anaplastic large cell lymphomas (ALCL) including 2 cases of probable NK-like T cell lineage, 3 lymphomatoid papulosis, 2 CD56 (-) T cell ACLs and 7 subcutaneous panniculitic T-cell lymphomas (SPTL) by Revised European-American Lymphoma (REAL) classification and recent concept of further classification into NK-cell lineage. One case of T-cell pseudolymphoma as a negative control was also negative in EBER. CONCLUSION: High incidence of EBV was observed in primary or secondary CTCLs in Koreans, with predilection for nasal and nasal type TNKL. In MFs, an erythrodermic MF with fatal outcome was associated with EBV and the EBV detection might reflect worse prognosis in MFs as seen in an aggressive course of nasal and nasal type TNKLs.
Cell Lineage ; Classification ; Fatal Outcome ; Herpesvirus 4, Human* ; Humans ; In Situ Hybridization ; Incidence ; Lymphoma ; Lymphoma, Large-Cell, Anaplastic ; Lymphoma, T-Cell ; Lymphoma, T-Cell, Peripheral ; Lymphomatoid Papulosis ; Lymphoproliferative Disorders* ; Mycosis Fungoides ; Prognosis ; Pseudolymphoma ; RNA* ; Skin ; T-Lymphocytes*

No abstract available.
Cervix Uteri* ; Embryo Transfer* ; Embryonic Structures* ; Female ; Fertilization in Vitro* ; Follicular Fluid* ; Humans* ; Spermatozoa* ; Spouses*

Intussusception in Schoenlein-Henoch Vasculitis is of interest because of its rarity & the importance of making what may be a difficult diagnosis. We recently experienced one case of Intussusception in Schoenlein-Henoch Vasculitis, who was a 3 year-old girl treated with mannual reduction following surgical operation & we reviewed some literature.
Child, Preschool ; Diagnosis ; Female ; Humans ; Intussusception ; Vasculitis*

STATEMENT OF PROBLEM: Peri-implant marginal bone loss is an important factor that affects the success of implants in esthetics and function. Various efforts have been made to reduce this bone loss by improving implant design and surface texture. Previous studies have shown that early marginal bone loss is affected by implant neck designs. PURPOSE: The purpose of this study was to examine the influence of laser microtexturing of implant collar on peri-implant marginal bone loss. MATERIALS AND METHODS: Radiographical marginal bone loss was examined in patients treated with implant-supported fixed partial dentures. Marginal bone level was examined with 101 implant fixtures installed in 53 patients at three periods(at the time of implantation, prosthetic treatment and 6-month after loading). Four types of implants were examined. The differences of bone loss between implants(ITI standard) with enough biologic width and implants(ITI esthetic plus, Silhouette IC, Silhouette IC Laser-Lok(TM)) with insufficient biologic width have been compared. Resorption angles were examined at the time of prosthetic delivery and 6-month after loading. RESULTS AND CONCLUSION: Within the limitation of this study, the following results were drawn. 1. The marginal bone loss of ITI standard and Silhouette IC Laser-Lok(TM) was less than that of ITI esthetic plus and Silhouette IC(P<0.05). The marginal bone loss between ITI standard and Silhouette IC Laser-Lok(TM) had no significant statistical difference(P>0.05). There was no significant statistical difference between marginal bone loss of ITI esthetic plus and Silhouette IC(P>0.05). 2. There was no significant difference in marginal bone loss between maxilla and mandible(P>0.05). 3. There was no significant difference in resorption angle among four types of implants(P>0.05). The marginal bone of implants with supracrestal collar design of less than that of biologic width had resorbed more than those with sufficient collar length. The roughness and laser microtexturing of implant neck seem to affect these results. If an implant with collar length of biologic width, exposure of fixture is a possible complication especially in the anterior regions of dentition that demand high esthetics. Short smooth neck implant are often recommended in these areas which may lack the distance between microgap and the marginal bone level. In these cases, the preservation of marginal bone must be put into consideration. From the result of this study, it may be concluded that laser microtexturing of implant neck is helpful in the preservation of marginal bone.
Bone and Bones ; Dental Implants ; Dentition ; Denture, Partial, Fixed ; Esthetics ; Humans ; Maxilla ; Neck

PURPOSE: Intrathecal morphine pump (ITMP) infusion therapy is efficient in managing malignant and nonmalignant chronic pain refractory to standard treatment. However, the high cost of an ITMP is the greatest barrier for starting a patient on ITMP infusion therapy. Using the revised Korean reimbursement guidelines, we investigated the cost effectiveness of ITMP infusion therapy and conducted a patient survey. MATERIALS AND METHODS: A retrospective chart review of 12 patients who underwent ITMP implantation was performed. Morphine dose escalation rates were calculated, and numeric rating scale (NRS) scores were compared before and after ITMP implantation. We surveyed patients who were already using an ITMP as well as those who were candidates for an ITMP. All survey data were collected through in-person interviews over 3 months. Data on the cost of medical treatment were collected and projected over time. RESULTS: The NRS score decreased during the follow-up period. The median morphine dose increased by 36.9% over the first year, and the median time required to reach a financial break-even point was 24.2 months. Patients were more satisfied with the efficacy of ITMP infusion therapy than with conventional therapy. The expected cost of ITMP implantation was KRW 4000000-5000000 in more than half of ITMP candidates scheduled to undergo implantation. CONCLUSION: The high cost of initiating ITMP infusion therapy is challenging; however, the present results may encourage more patients to consider ITMP therapy.
Adult ; Aged ; Analgesics, Opioid/*administration & dosage/economics/therapeutic use ; Chronic Pain/*drug therapy ; Cost-Benefit Analysis ; Female ; Humans ; Infusion Pumps, Implantable/*economics ; Injections, Spinal ; Male ; Middle Aged ; Morphine/*administration & dosage/economics/therapeutic use ; Pain Management/*methods/trends ; Patient Satisfaction ; Republic of Korea ; Retrospective Studies ; Surveys and Questionnaires ; Treatment Outcome

PURPOSE: During stimulated in vitro fertilization (IVF) cycle, up to 30% of the recovered oocytes are immature ones which have poor fertilization capacity; however, the precise influencing factors are largely unknown. Here, we analyzed the association of oocyte immaturity with woman's age in IVF cycles stimulated by single regimen. MATERIALS AND METHODS: A total of one-hundred ninety five IVF cycles stimulated by recombinant FSH and GnRH antagonist protocol between 2003 and 2009 were analyzed retrospectively. The mean age of women was 34.2+/-4.0 (26-45 years). After triggering by exogenous hCG, an ultrasound-guided retrieval of oocytes was performed 35-36 hours later. All clinical data were stratified by woman's age; group I: < or =30 (n=36), II: 31-35 (n=83), III: 36-40 (n=57), and IV: > or =41 (n=19). RESULTS: The total retrieved oocytes, as well as immature oocytes, were significantly lower in group IV, however, the mean % of immature oocytes was significantly higher in group IV than other age groups. Oocyte immaturity tended to decrease as increasing age in women aged 40 years or less. CONCLUSION: In stimulated IVF cycle, much higher oocyte immaturity was noted in women aged 41 years or more.
Adult ; Age Factors ; Female ; Fertilization in Vitro/*methods ; Follicle Stimulating Hormone/therapeutic use ; Gonadotropin-Releasing Hormone/therapeutic use ; Humans ; Middle Aged ; Oocyte Retrieval/*methods ; Oocytes/*cytology/*physiology ; Ovulation Induction/*methods ; Pregnancy ; *Pregnancy Rate ; Retrospective Studies

PURPOSE: To investigate the direct relationship between the follicular fluid (FF) level of soluble human leukocyte antigen G (HLA-G) and fertilizability of the corresponding oocyte as well as the morphological quality of the corresponding embryo. MATERIALS AND METHODS: Sixty-three patients were stimulated with recombinant FSH combined with gonadotropin-releasing hormone (GnRH) agonist long (n=5) or antagonist protocol (n=58) for standard in vitro fertilization (IVF). At the time oocyte retrieval, follicular fluid was obtained from single dominant follicle in 63 patients, and the level of soluble HLA-G was measured by sandwich enzyme-liked immunosorbent assay (ELISA). Normal fertilization and individual embryo quality were evaluated, and were graded to four categories by morphological criteria (the embryo with symmetrical blastomeres and no fragmentation were assigned as grade A). Good-quality embryo was defined as those with grade A or B. RESULTS: Soluble HLA-G was not detected in 15 FF samples. In the group with positive FF soluble HLA-G (sHLA-G) (n=48), high levels of sHLA-G (>117.758 U/mL) could predict the failure of fertilization with statistical significance {area under the curve (AUC) 0.676, 95% confidence interval (CI) 0.525-0.804}. However, the FF sHLA-G level was not related with the formation of good-quality embryo. CONCLUSION: High level of FF sHLA-G could predict the fertilization failure of the corresponding oocyte, but was not related with the formation of good-quality embryo.
Adult ; Enzyme-Linked Immunosorbent Assay ; Female ; Follicular Fluid/*metabolism ; HLA-G Antigens/*metabolism ; Humans ; Oocytes/*cytology/physiology ; Ovarian Follicle/*cytology/physiology

OBJECTIVE: This study was performed to assess whether uterine intraendometrial or intramyometrial arterial blood flow impedance in Doppler sonography is related to the outcomes of IVF-ET cycles. METHODS: A total of 24 patients undergoing IVF-ET was recruited for the study. All patients received controlled ovarian hyperstimulation(COH) with GnRH agonist and gonadotropins. Doppler sonographic examinations were performed by using Combison 530(Medison) with 5.5 MHz transvaginal probe. Pulsatility index(PI) was evaluated for uterine, radial, and spiral arteries on the days of hCG administration, oocyte retrieval, and embryo transfer(ET). Serum E2 level was assayed on the hCG day. RESULTS: The overall pregnancy rate after IVF-ET was 29.2%(7/24). There was no significant difference in PI of uterine artery between pregnant and nonpregnant groups, No pregnancy occurred in 4(16.7%) patients without intraendometrial or subendometrial blood flow. Compared with nonpregnant group, PI of radial artery on the hCG day and PI of spiral artery on the hCG and oocyte retrieval days were significantly lower in pregnant group. There were no significant correlations between Serum E level on the hCG day and Pl of any three arteries. CONCLUSION: This study suggests that the Doppler sonographic parameter, PI, of intraendometrial and intramyometrial arteries are more useful than that of uterine artery not only in predicting the success of IVF-ET, but also in assessing the endometrial receptivity.
Arteries* ; Electric Impedance ; Embryo Transfer* ; Embryonic Structures* ; Fertilization in Vitro* ; Gonadotropin-Releasing Hormone ; Gonadotropins ; Humans ; Oocyte Retrieval ; Pregnancy Rate ; Pregnancy* ; Radial Artery ; Serum ; Ultrasonography ; Ultrasonography, Doppler* ; Uterine Artery