1.Interrelationship among sperm motility, sperm morphology and hypoosmotic swelling test in male infertility evaluation and their usefulness in predicting male fertility potential.
Doo Seok CHOI ; Shin Yong MOON ; Yoon Seok CHANG
Korean Journal of Obstetrics and Gynecology 1993;36(7):2497-2509
No abstract available.
Fertility*
;
Humans
;
Infertility, Male*
;
Male
;
Male*
;
Sperm Motility*
;
Spermatozoa*
2.Growth promoting effect of recombinant methionyl-growth hormone in children with chronic renal failure.
Jeon Seok HAN ; Yong CHOI ; Hyung Ro MOON
Journal of the Korean Pediatric Society 1992;35(10):1355-1360
No abstract available.
Child*
;
Human Growth Hormone
;
Humans
;
Kidney Failure, Chronic*
3.A Clinical Study on the Diaphyseal Fractures Treated with Compression Plate
Jang Seok CHOI ; Moon Sik HAHN ; Jay Suk CHANG
The Journal of the Korean Orthopaedic Association 1980;15(4):675-682
Most orthopedic surgeons were aimed at the rigid internal fixation on the surgical treatment of the fracture. And the compression plate was developed and regarded as an excellent rigid internal fixation device by its advantages of accurate anatomical reduction, early joint mobilization and shortening of the duration of the fracture healing, which are chief aim of A.S.I.F. method. During the period of January 1970 to December 1979, 67 cases of diaphyseal fractures of the long bones were treated with compression plate according to A.S.I.F. method at the Department of Orthopedic Surgery, College of Medicine, Seoul National University and results were obtained as follows: 1. The age of patient was ranged from 15 to 77, and the highest incidence was in the 3rd decade male group (31.4%). 2. Old fracture cases were slightly more than fresh cases, and the fresh femur fracture was the commonest. 3. The periods of the postop immobilization of fresh fractures were 3.7 weeks in humerun fracture, 6.3 weeks in forearm fractures, 8.7 weeks in femur fracture and 7.0 week in tibia fracture, and in old fractures about 4 weeks was longer than fresh fractures. 4. The bony union was accomplished in all cases between 8 week and 24 week. 5. The complication were 4 superficial infections, 4 deep infections, 1 delayed union and 9 joint stiffnesses. 6. Compression plate fixation is considered as an excellent method for the treatment of the fractures of the long bones.
Clinical Study
;
Femur
;
Forearm
;
Fracture Healing
;
Humans
;
Immobilization
;
Incidence
;
Internal Fixators
;
Joints
;
Male
;
Methods
;
Orthopedics
;
Seoul
;
Surgeons
;
Tibia
4.Predictive value of serum beta-hCG level in pregnancies following in vitro fertilization and embryo transfer.
Seok Hyun KIM ; Chang Suk SUH ; Doo Seok CHOI ; Young Min CHOI ; Chang Jae SHIN ; Jung Gu KIM ; Shin Yong MOON ; Jin Yong LEE ; Yoon Seok CHANG
Korean Journal of Fertility and Sterility 1992;19(1):41-48
No abstract available.
Embryo Transfer*
;
Embryonic Structures*
;
Fertilization in Vitro*
;
Pregnancy*
5.A case of successfully resected retroperitoneal hemangiopericytoma.
Il Jung CHOI ; Myoung Seok HAN ; Moon Seok CHA
Korean Journal of Obstetrics and Gynecology 2009;52(7):771-775
Hemangiopericytoma is a rare mesenchymal neoplasm, accounting for about 1% of vascular tumor. Hemangiopericytoma is known to be derived from the vascular pericyte and occurs most commonly lower extremities, pelvis and retroperitoneum. Surgical radical excision is the treatment of choice. Because of malignant features of hemangiopericytoma, long term and close follow-up is important. We report a case of successfully resected retroperitoneal hemangiopericytoma.
Accounting
;
Follow-Up Studies
;
Hemangiopericytoma
;
Lower Extremity
;
Pelvis
;
Pericytes
6.The Effect of Sex Steroid Hormone on the Expression of Insulin-Like Growth Factor Binding Preteins mRNA in the Explant Cultured from Human Uterine Myoma and Adjacent Normal Myometrium.
Jin Yong LEE ; Jung Koo KIM ; Chang Seok SEO ; Seok Hyun KIM ; Young Min CHOI ; Shin Yong MOON
Journal of Korean Society of Endocrinology 1998;13(1):34-44
BACKGROUND: Sex steroid hormones are believed to play an important role in the genesis and growth of uterine myoma. Several studies suggest a possible role of insulin-like growth factor(IGF) as a mediator of estradiol in uterine myama. We have recently demonstrated that some IGF binding proteins(IGFRPs) messenger ribonucleic acid(mRNA) expressions in myoma are dependent on the in vivo esttogen status. The purposes of this study are to evaluate the in vitro effects of sex steroid hormones including estrogen on the IGFBPs gene expression in tissues from uterine myoma and adjacent normal myometrium. METHODS: Tissues from myoma and adjacent normal myometrium of patients with uterine myoma during early proliferative phase of menstrual cycle were cultured in the absence(control) and presence of 17b-estradiol(10M/L) or/and progesterone(10M/L) for 3 days. The IGFBPs mRNA expressions in these explants were analyzed by Nothern blot using specific human complementary deoxyribonucleic acid(cDNA) probes. RESULTS: The addition of 17b-estradiol, progesterone alone and in combination to conditioned media of explants from myoma and adjacent normal myornetrium did not result in any changes in the expression of IGFBP-2, IGFBP-4, IGFBP-5, and IGFBP-6 mRNA. With progesterone addtion, lGFBP-3 rnRNA expression was significantly reduced in myoma explant but not in adjacent ncemal myometrium explant. There was no significant change in the IGFBP-3 mRNA expression with 17b-estradiol and with the combination of both 17b-estradiol and progesterone. CONCLUSION: 17b-estradiol does not affect IGFBPs gene expression in the myoma and adjacent normal myometrium explant regardless of the presence of progesterone in vitro. However progesterone alone induces a decrease in IGFBP-3 synthesis in myoma explant.
Animals
;
Culture Media, Conditioned
;
Estradiol
;
Estrogens
;
Female
;
Gene Expression
;
Gonadal Steroid Hormones
;
Humans*
;
Insulin-Like Growth Factor Binding Protein 2
;
Insulin-Like Growth Factor Binding Protein 3
;
Insulin-Like Growth Factor Binding Protein 4
;
Insulin-Like Growth Factor Binding Protein 5
;
Insulin-Like Growth Factor Binding Protein 6
;
Insulin-Like Growth Factor Binding Proteins
;
Leiomyoma*
;
Menstrual Cycle
;
Mice
;
Myoma
;
Myometrium*
;
Progesterone
;
RNA, Messenger*
7.Effects of Insulin-like Growth Factor in Peritoneal Fluid of Patients with Endometriosis on the Proliferation of Endometrial Stromal Cells.
Jung Gu KIM ; Chang Seok SUH ; Seok Hyun KIM ; Young Min CHOI ; Shin Yong MOON ; Jin Yong LEE
Korean Journal of Fertility and Sterility 1999;26(3):331-338
The purposes of this study were to evaluate the effects of insulin-like growth factor (IGF)s in peritoneal fluid (PF) from patients with and without endometriosis on the proliferation of endometrial stromal cells and to investigate the effects of type I IGF receptor antibody on the response of endometrial stromal cells to PF from patients with endometriosis. IGFs in PF from patients with endometriosis (n=14) and without endometriosis (n=10) were measured by immunoradiometric assay and PF samples were divided into low IGF-I PF group (less than 85 ng/ml) and high IGF-I PF group (more than 85 ng/ml). Endometrial stromal cells from patients without endometriosis were cultured in serum free media in the presence or absence of 1% PF and thymidine incorporation test were used to evaluate the proliferation of endometrial stromal cells. Also cultures were incubated with type I IGF receptor monoclonal antibody (alpha IR3) before adding PF. PF from patients with endometriosis and without endometriosis increased thymidine incorporation in endometrial stromal cells. In patients with endometriosis, high IGF-I PF group had high IGF-II levels and resulted in higher thymidine incorporation than low IGF-I PE and low IGF-I PF group was noted in patients without endometriosis. There was not a significant correlation between increase in thymidine incorporation and IGF-I levels in PF from patients without endometriosis but in PF from patients with endometriosis. Preincubation with alphaIR3 significantly inhibited the mitogenic response of endometrial stromal cells to PF. Our data indicate that IGF-I in PF may be involved in the growth of ectopic endometrium in patients with endometriosis.
Ascitic Fluid*
;
Culture Media, Serum-Free
;
Endometriosis*
;
Endometrium
;
Female
;
Humans
;
Immunoradiometric Assay
;
Insulin-Like Growth Factor I
;
Insulin-Like Growth Factor II
;
Stromal Cells*
;
Thymidine
8.The Effect of Finasteride, Tamsulosin and Doxazosin Therapy on Sexual Function in Patients with Benign Prostatic Hyperplasia.
Korean Journal of Urology 2004;45(8):777-782
Purpose: The aim of this study was to evaluate the effect on sexual function after finasteride, tamsulosin, doxazosin single or combination therapy according the sexual function state before these therapies. Materials and Methods: This study included 192 men with benign prostatic hyperplasia (BPH) who had neither diabetes mellitus nor hypertension. All patients were classified into 2 groups according to their erectile dysfunction (ED) severity based on IIEF-5 before treatment; the above mild ED group (severe + moderate + mild to moderate) and mild or no ED group. The patients were assessed by IIEF inventory at the baseline and 1, 3 and 6 months after finasteride, tamsulosin, doxazosin single or combination therapies, respectively. Results: In the above mild erectile dysfunction group the mean IIEF score was significantly decreased at 3 and 6 months with finasteride single therapy, at 6 months with finasteride-tamsulosin combination therapy and at 3 and 6 months with finasteride-doxazosin combination therapy (p<0.05). In the mild or no erectile dysfunction group the mean IIEF score did not change significantly with any of the medications. Conclusions: Sexual function tended to decrease in the above mild ED group with finasteride single or combination therapy. Therefore, the patients in this group should be treated carefully at the beginning of these therapies.
Diabetes Mellitus
;
Doxazosin*
;
Erectile Dysfunction
;
Finasteride*
;
Humans
;
Hypertension
;
Male
;
Prostatic Hyperplasia*
9.Medical Management of Acute Liver Failure associated with Hepatitis B Virus Infection.
Korean Journal of Hepato-Biliary-Pancreatic Surgery 2009;13(1):13-16
No abstract available.
Hepatitis
;
Hepatitis B
;
Hepatitis B virus
;
Liver Failure, Acute
10.A case of malignant Mixed Germ Cell-Sex Cord stromal Tumor of the Ovary in a Normal Female Adult.
Korean Journal of Obstetrics and Gynecology 1997;40(4):907-913
The authors observed a case of malignant mixed germ cell-sex cord stromal tumor occuring in a 43-year-old woman. A laparotomy perfomed on August 3, 1994, revealed a large roughly round, partially ruptured tumor in the right ovary. The tumor mass weighed 330 gm and its dimensions were 11X9X8 cm. Tumors composed of germ cells and sex cord stroma intimately associated togther are very rare. Interest in these gonadal tumors that are distinct from gonadoblastoma has mouted in recent years. The tumor behaves in a benign clinical course and occurs predominantly in female infats and children with normal 46.XX karyoytype. This tumor differs from gonadobalstoma in its histologic pattern, absence of regresive changes, lack of association with other neoplastic germ cell elements, and occurrence in normal gonads.Histologically, the mass was characterized by an intimate admixutr of germ cells and sex cord stromal cells. The lesion had many predominant setoli tuble formations and lipid cell changes. But it lacked Call-Exner like bodies, calcification and byalinization that charaterize gonadoblastomas. Typical areas of dysgemonoma and endodermal sinus tumor were also present the patient subsequelty received chemotherapy(blemycin,etoposied, and cisplatin administered in 5cycles), The patient was symptom free two yares after surgery and chemotherapy.
Adult*
;
Child
;
Cisplatin
;
Drug Therapy
;
Endodermal Sinus Tumor
;
Female
;
Female*
;
Germ Cells
;
Gonadoblastoma
;
Gonads
;
Humans
;
Laparotomy
;
Ovary*
;
Stromal Cells