1.A Cytogenetic Study of Amenorrhea.
Kyung Soon LEE ; Jung Ho HAN ; Shin Yong MOON
Korean Journal of Fertility and Sterility 1999;26(3):467-474
OBJECTIVEs: Cytogenetic investigations were carried out on 770 women with primary (n=560) and secondary amenorrhea (n=210) to determine the frequency of chromosomal or genetic causes of amenorrhea. MATERIALS AND METHODS: In 770 women with primary amenorrhea (n=560) and secondary amenorrhea (n=210), chromosomal analysis were performed. RESULTS: 1) The most prevalent age group is 16-20 years of age group with primary amenorrhea and 26-30 years of age group with secondary amenorrhea. 2) Out of 560 cases of primary amenorrhea, 343 cases (61.3%) had the normal chromosome constitution and 217 cases (38.7%) had the abnormal chromosome constitution including 46,XY. 3) In 217 cases of abnormal chromosome of primary amenorrhea, 57 cases (26.3%) had 45,X and 34 cases (15.8%) had the 46,XY, 24 cases (11.0%) had 45,X/46,X,i (Xq), 23 cases (10.6%) had 45,X/46,X,+mar and 14 cases (6.6%) had 45,X/46,XY. 4) Out of 210 cases of secondary amenorrhea, 181 cases (86.2%) had the normal chromosome constitution and 29 cases (13.8%) had 45,X/46,XX. CONCLUSION: High percentage of chromosomal abnormalities was diagnosed in primary amenorrhea and most of them were sex chromosome anomalies. In secondary amenorrhea, the prevalence was lower than primary amenorrhea, so a preselection of patients with secondary amenorrhea for cytogenetic investigations seems to be necessary.
Amenorrhea*
;
Chromosome Aberrations
;
Constitution and Bylaws
;
Cytogenetics*
;
Female
;
Humans
;
Prevalence
;
Sex Chromosomes
2.Aspiration Biopsy Cytology of Malignant Fibrous Histiocytoma.
Moon Hyang PARK ; Eun Kyung HONG ; Jung Dal LEE
Korean Journal of Pathology 1986;20(3):332-335
Cytologic findings of malignant cells obtained by fine needle aspiration from a huge retroperitoneal malignant fibrous histiocytoma were described. The smears contained numerous malignant cells, isolated or in clusters, in a bloody background. The malignant cells had abundant pleomorphic foamy or acidophilic cytoplasm with occasional multilobated vesicular nuclei and prominent nucleoli. Dual differentiation, both histiocytic and fibroblastic types, and neutrophilic inflammatory background were diagnostic of this neoplasm. The report indicated that study of aspiration cytology specimen from a soft tissue tumor was a valuable adjunct to histologic examination.
Biopsy
3.Pulmonary lymphangioleiomyomatosis: high-resolution CT findings.
Woo Kyung MOON ; Jung Gi IM ; Man Chung HAN
Journal of the Korean Radiological Society 1991;27(4):543-546
No abstract available.
Lymphangioleiomyomatosis*
4.The clinical significance of serum CA125 and CA19-9 levels in endometriosis.
Tae Jung KANG ; Hye Sung MOON ; Kyung Ah JEONG ; Hye Won JUNG ; Jung Ja AHN
Korean Journal of Obstetrics and Gynecology 2000;43(7):1181-1188
OBJECTIVE: Because endometriosis is difficult to diagnose and has a high recurrence rate after treatment, a reliable serum marker of endometriosis is necessary. Therefore, the aim of this study is to measure the serum levels of CA125 and CA19-9 in patients with endometriosis before and after treatment and during recurrence, and to assess the usefulness of these levels in the diagnosis, clinical follow up and prediction of recurrence in endometriosis. METHODS: Eighty-eight patients who visited the department of Obstetrics and Gynecology of Ewha Mokdong Hospital from January 1994 to December 1998 and were diagnosed as endometriosis by laparoscopy or explo-laparotomy were enrolled as subjects. A retrospective analysis of serum CA125 and CA19-9 levels at 1 month before and 3 to 6 months after initiation of treatment was done. RESULTS: The serum CA125 and CA19-9 levels of endometriosis group(81.0+/-252.5, 36.6+/-53.4 ; mean+/-2SD, U/ml) before treatment was significantly higher than control group(11.6+/-12.8, 9.4+/-8.6)(p<0.05). Overall sensitivity rate for CA125, CA19-9 levels and both was 53.4%, 42.9% and 64.3% respectively. The sensitivity rate for endometriosis, stage 3 and 4(85.4%, 55.0%) was significantly higher than that, stage 1 and 2(p<0.05). The serum CA125 level in endometriosis group showed a significant increment according to stages(p<0.05) while the serum CA19-9 level showed an increasing trend(p=0.055) and both levels decreased significantly after treatment(p<0.05). The serum CA125 level was also higher at recurrence after treatment(p<0.05). CONCLUSIONS: The serum CA125 and CA19-9 levels are a useful marker for diagnosing severity of disease, monitoring efficacy of treatment and predicting recurrence in endometriosis.
Biomarkers
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Diagnosis
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Endometriosis*
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Female
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Follow-Up Studies
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Gynecology
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Humans
;
Laparoscopy
;
Obstetrics
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Recurrence
;
Retrospective Studies
5.A modified elution method for determining the presence of fetal red blood cells.
No Bum LEE ; Hye Kyung LEE ; Jung Hwan SHIN ; Moon Il PARK ; Sung Ro CHUNG ; Hyung MOON
Korean Journal of Perinatology 1992;3(2):72-76
No abstract available.
Erythrocytes*
6.A Cytogenetic Study of Recurrent Spontaneous Abortion.
Kyung Soon LEE ; Jung Ho HAN ; Sun Kyung OH ; Shin Yong MOON
Korean Journal of Fertility and Sterility 1999;26(3):475-481
OBJECTIVE: The purpose of this investigation is to determine the frequency of chromosomal or genetic causes of recurrent spontaneous abortion. METHODS : A cytogenetic study was made in of 921 couples for 13 years from January 1984 to December 1997 in which the woman was ascertained to have had two or more spontaneous abortions at our Cytogenetic Laboratory, Institute of Reproductive Medicine and Population, Seoul National University. RESULTS : The overall incidence of chromosome anomaly was 80 out of 921 (8.7%). There were 34 cases (3.69%) of reciprocal balanced translocation and 13 cases (1.41%) of Robertsonian translocation. Also 17 cases (1.85%) of inversion and 5 cases (0.54%) of X chromosome mosiacism was observed. In the case of reciprocal balanced translocation, chromosome 8,6,7,13 were preferentially involved over others. And in the case of Robertsonian translocation, chromosome 13 was preferentially involved. CONCLUSION: Our study demonstrates that cytogenetic analysis is indicated in couples with 2 or more spontaneous abortion and about half of these disorders are reciprocal balanced or Robertsonian translocations.
Abortion, Spontaneous*
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Chromosomes, Human, Pair 13
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Cytogenetic Analysis
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Cytogenetics*
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Family Characteristics
;
Female
;
Humans
;
Incidence
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Pregnancy
;
Reproductive Medicine
;
Seoul
;
X Chromosome
7.Clear Cell Basal Cell Carcinoma Arising in Pre-existing Nevus Sebaceus.
Chae Young WON ; Hanmi JUNG ; Ji Hae LEE ; Jung Min BAE ; Kyung Moon KIM
Korean Journal of Dermatology 2016;54(10):836-837
No abstract available.
Carcinoma, Basal Cell*
;
Nevus*
8.A Case of Borst-Jadassohn Pheonomenon Represented in Bowen Disease.
Hanmi JUNG ; Chae Young WON ; Hyerim KO ; Ji Hae LEE ; Jung Min BAE ; Kyung Moon KIM
Korean Journal of Dermatology 2016;54(2):162-163
No abstract available.
Bowen's Disease*
9.Giant Extra-Capsular Synovial Chondroma of the knee joint: A Case Report
Yak Woo ROH ; Byung Ki MOON ; Jung Il OH ; Kyung Chan LEE ; Woo Koo JUNG
The Journal of the Korean Orthopaedic Association 1981;16(1):178-181
Extra-capsular synovial chondroma is a rare condition in which metaplastic cartilaginous mass is formed by the cartilage nodule within the synovial connective tissue break through the joint capsule and continue to proliferate. The authors have experienced a case of giant extracapsular synovial chondroma, affecting the knee joint of 54 years old woman. A case of giant extra-capsular synovial chondroma is reported with brief review of literature.
Cartilage
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Chondroma
;
Connective Tissue
;
Female
;
Humans
;
Joint Capsule
;
Knee Joint
;
Knee
10.Choledocal Cyst Diagnosed by Endoscopic Retrograde Cholangiopancreatography.
Seung Jung BARK ; Jai Bock JUNG ; Young Myung MOON ; Jin Kyung KANG ; In Suh PARK ; Heung Jai CHOI ; Kyung Sik LEE
Korean Journal of Gastrointestinal Endoscopy 1981;1(1):33-40
Choledochal cyst of the common bile duct is usually considered to be large cystic dilatation that extends from the wall of the common bile duct. Choledochal cyst is a very rare cond.ition in adult, These cysts are commonly distinctive in childran under the age of ten. Even in this age group they are considered rare. The classicajl triad of a choledochal cyst inclule pain, jaundice and a palpable right upper quadrant mass. This triad was found in only 21~63% and the most common finding is jaundice. Diagnoais of choledochal cyst usually is made during laparotomy, In nonjaundiced patients, oral cholangiogram and/or intravenous cholangiogram may yield the diagnosis. In jaundiced patiente where the diagnosis may be more difficult to make, one may consider doing ERCP and/or percutaneous transhepatic cholangiogram. The percutaneous transhepatic cholangiogram seems to be very helpful in diagnosing jaundiced patients. It is being used more and more in recent years but this method is not without complication. With advent of ERCP, visualization of the biliary tree has become a simple procedure when performed by expert endoscopists. To our knowlege, no previous case of choledochal cyst diagnosed by ERCP has been reported. yet in our country This paper reports 4 cases of choledochal cyst diagnosed by ERCP.
Adult
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Biliary Tract
;
Cholangiopancreatography, Endoscopic Retrograde*
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Choledochal Cyst
;
Common Bile Duct
;
Diagnosis
;
Dilatation
;
Humans
;
Jaundice
;
Laparotomy