A characteristic dermatosis of infancy and childhood has recently been reported as many names, called juvenile plsntar dermatoais, recurrent juvenile eezema of hands and feet, and atopic winter feet in children. However, the clinicsl and epidemiological features of the published cases are strikingly the same The etiology of the diseaee remains unclear. The role of atopy appears to be highly controversial. We have observed 11 patients with juvenile plantar dermatosis and sumrnarized the results as followa: 1. The disease was found mainly in female children (3 boys, 8 girls) between 1 and 18 years old. Duration of the disease ranged from 1 month to 10 years. 2. The lesions occured or were exacerbated dunng the winter in 9 of them. 3. The disease affected symmetrically on the pressure areas of the feet, mainly the forefeet and toes, the lateral margins of the soles, and the heels. Five of our patients also showed the lesions on the hands simultaneously. 4. We have found a high incidence of atopy among the patients or close relative. Nine patients had a personal history of atopy and 5 gatients also had a history of atopy in the first degree relatives. 5. The serum IgE value increased in one of 6 patients determined. From the above clinical findinge, it is evident that juvenile plantar dermatosis is a true localized atopic dermatitis but also a primary irritant contact derrnatitis to which atopics are prone but which may occur in susceptible non-atopics.
Adolescent ; Child ; Dermatitis, Atopic ; Female ; Foot ; Hand ; Heel ; Humans ; Immunoglobulin E ; Incidence ; Skin Diseases* ; Toes

We described here a case of hyperkeratosis of the nipple and areola. A 23-year- old woman had a verrucous thickening and brownish discoloration on her right nipple and areola that had been present for 4 yeare. The only symptom was an intermittent mild itching sensation. The patient had no other additioa.al hyperkeratotic conditians. She was not married and had never had a pregnancy. Riopsy spccimen showed papillomatous elongation of the epidermis and edema, of the underlying papillary eonnective tissue. The epidermis was parakeratotic and hyperpigmented, and showed focal intercellular and intracellular edema. The present case seems to be the nevoid form by the Levy-Franckel classification. The world literature was briefly reviewed.
Classification ; Edema ; Epidermis ; Female ; Humans ; Nipples* ; Pregnancy ; Pruritus ; Sensation

No abstract available.
Humans ; Infant, Newborn*

A case of hereditary papulotranslucent acrokeratoderma, a variant of familiaI punctate keratoderma, is presented. A 20-year-old female patient had a five-year history of persistent, asymptomatic, yellowish-white translucent papules and plaques on the thenar and hypothenar eminences and knuckles of both hands, and on the dorsa of proximal interphalangeal joints of both feet. She also had a vitiligo lesion on the left side of the face of 1.5 years duration. Her elder brother also had similar papular skin lesions on both hands and feet. Histologic section of a papule from the right thenar eminence showed marked hyperkeratosis, hypergranulosis, and acanthosis of the epidermis.
Female ; Humans

No abstract available.
Cervix Uteri* ; Female ; Fibrin Tissue Adhesive*

No abstract available.
Erythrocytes*

Gross deciduosis in pregnancy is rare. A case of disseminated deciduosis peritonei studied by light and transmission electron microscopy is reported. The pathogenesis of deciduosis peritonei and relationship with leiomyomatosis peritonealis disseminata are discussed in view of the present findings and those previously reported.
Pregnancy ; Female ; Humans

OBJECTIVEs: Cytogenetic investigations were carried out on 770 women with primary (n=560) and secondary amenorrhea (n=210) to determine the frequency of chromosomal or genetic causes of amenorrhea. MATERIALS AND METHODS: In 770 women with primary amenorrhea (n=560) and secondary amenorrhea (n=210), chromosomal analysis were performed. RESULTS: 1) The most prevalent age group is 16-20 years of age group with primary amenorrhea and 26-30 years of age group with secondary amenorrhea. 2) Out of 560 cases of primary amenorrhea, 343 cases (61.3%) had the normal chromosome constitution and 217 cases (38.7%) had the abnormal chromosome constitution including 46,XY. 3) In 217 cases of abnormal chromosome of primary amenorrhea, 57 cases (26.3%) had 45,X and 34 cases (15.8%) had the 46,XY, 24 cases (11.0%) had 45,X/46,X,i (Xq), 23 cases (10.6%) had 45,X/46,X,+mar and 14 cases (6.6%) had 45,X/46,XY. 4) Out of 210 cases of secondary amenorrhea, 181 cases (86.2%) had the normal chromosome constitution and 29 cases (13.8%) had 45,X/46,XX. CONCLUSION: High percentage of chromosomal abnormalities was diagnosed in primary amenorrhea and most of them were sex chromosome anomalies. In secondary amenorrhea, the prevalence was lower than primary amenorrhea, so a preselection of patients with secondary amenorrhea for cytogenetic investigations seems to be necessary.
Amenorrhea* ; Chromosome Aberrations ; Constitution and Bylaws ; Cytogenetics* ; Female ; Humans ; Prevalence ; Sex Chromosomes

Cytologic findings of malignant cells obtained by fine needle aspiration from a huge retroperitoneal malignant fibrous histiocytoma were described. The smears contained numerous malignant cells, isolated or in clusters, in a bloody background. The malignant cells had abundant pleomorphic foamy or acidophilic cytoplasm with occasional multilobated vesicular nuclei and prominent nucleoli. Dual differentiation, both histiocytic and fibroblastic types, and neutrophilic inflammatory background were diagnostic of this neoplasm. The report indicated that study of aspiration cytology specimen from a soft tissue tumor was a valuable adjunct to histologic examination.
Biopsy

Two cases of carcinoid tumor of the uterine cervix were reported with emphasis on the histologic, cytologic, histochemical and electron microscopic appearance of tumor cells. Based on the light microscopic findings, one case was a well differentiated carcinoid with acinus formation, and the other was a poorly differentiated anaplastic type, being composed of small cells similar to those of oat cell carcinoma of the lung. Both tumors demonstrated scattered argyrophilic cells on Grimelius stain, and contained neurosecretory granules on electron microscopy. They were in stages II b and IV, respectively, at the time of presentation. The latter patient was treated with vinblastin, platinol and bleomycin, but died in 9 months after the initial diagnosis. The former was lost to follow-up study. Importance of distinction between this highly malignant tumor and other varieties of cervical cancer was emphasized.
Follow-Up Studies