1.Overcrowding in emergency department.
Seok Joon JANG ; Moon Joon JANG ; Hahn Shick LEE
Journal of the Korean Society of Emergency Medicine 1992;3(1):71-78
No abstract available.
Emergencies*
;
Emergency Service, Hospital*
2.Rapid detection of mycobacterium tuberculosis in uncultured sputum samples by polymerase chain reaction.
Sung Joon KIM ; Jang Seong KIM ; Dahl Kyun OH ; Hae Ran MOON ; Hong Mo MOON
Journal of the Korean Society for Microbiology 1993;28(5):373-380
No abstract available.
Mycobacterium tuberculosis*
;
Mycobacterium*
;
Polymerase Chain Reaction*
;
Sputum*
3.A clinical study on the anti-hypertensive effect of fosinopril in essential hypertensive patients.
Su Youn NAM ; Jae Hwa CHO ; Joon Han SHIN ; Hyuck Moon KWON ; Yang Soo JANG ; Hyun Seung KIM
Korean Circulation Journal 1993;23(3):448-453
In order to investigate the efficacy and safety of oral fosinopril, a new phosphorus containing angiotensin converting enzyme inhibitor, a single dose of 10 to 20mg was administered in 23 hypertensive patients with diastotic blood pressure above 95mmHg and all other anti-hypertensive agents were not administered during 4 weeks of study. Blood pressure and heart rate were measured on the 2nd and 4th week of therapy. The complete blood count with platelet count, blood chemistry by SMA-12 and serum electrolytes were performed at the begining and 4th week of therapy. The urinalysis and electrocardiography were performed at the beginning and 4th week of therapy. Any kinds of side effects were actively questioned by the examining physicians. The following results were obtained : 1) At the beginning and 4th weeks of therapy, the average systolic and diastolic pressure were 170.0+/-17.6/101.6+/-6.1mmHg, 142.7+/-15.1/87.3+/-6.7mmHg respectively. The systolic and diastolic blood pressure were declined statistically significantly(p<0.05) throughout the period of treatment and diastolic blood pressure of all subjects except 3 patients(86%) was maintained below 90mmHg after 4th week of treatment. 2) There was no significant change in the pulse rate before and after therapy. 3) There were no significant changes in blood chemistry, serum electrolytes, hematologic findings, urinalysis and electrocardiographic findigns. 4) side effect were developed in 5 patients(23%) with dry cough, 3 patients(13%) with headache and 2 patients with facial edema but side effects were mostly mild in nature without potenitally serious episodes. These results suggested that antihypertensive therapy with onec-daily fosinopril was effective and well tolerated in essential hypertensive patients.
Antihypertensive Agents
;
Blood Cell Count
;
Blood Pressure
;
Chemistry
;
Cough
;
Edema
;
Electrocardiography
;
Electrolytes
;
Fosinopril*
;
Headache
;
Heart Rate
;
Humans
;
Hypertension
;
Peptidyl-Dipeptidase A
;
Phosphorus
;
Platelet Count
;
Urinalysis
4.A Case of Holoprosencephaly.
Byung Chun SUH ; Soon Sup JANG ; In Joon SEOL ; Soo Jee MOON ; Chong Moo PARK ; Seok Chol JEON
Journal of the Korean Pediatric Society 1987;30(6):695-700
No abstract available.
Holoprosencephaly*
5.A Case of Normal Volume Hydrocephalus with Recunent Shunt Obstruction Treated by Subtemporal Decompression.
Moon Chan KIM ; Choon Jang LEE ; Joon Ki KANG ; Jin Un SONG
Journal of Korean Neurosurgical Society 1982;11(1):61-64
The authors report a case of Normal Volume Hydrocephalus with recuring ventricular catheter obstraction treated by bilateral subtemporal craniectomy. Subtemporal craniectomy provide temporary relief from increased intracranial pressure while the same time encouraging dilatation of ventricle, would protect against further catheter obstruction by prevent trapping of catheter tip between the abutting ventricular wall. The patient had been followed-up for 2 years and postoperative result was excellent.
Catheter Obstruction
;
Catheters
;
Decompression*
;
Dilatation
;
Humans
;
Hydrocephalus*
;
Intracranial Pressure
6.Lipid Profiles in Primary Aldosteronism Compared with Essential Hypertension: Propensity-Score Matching Study
Sun Joon MOON ; Han Na JANG ; Jung Hee KIM ; Min Kyong MOON
Endocrinology and Metabolism 2021;36(4):885-894
Background:
There has been controversy regarding the association between primary aldosteronism (PA) and dyslipidemia and few studies considered the effects of diabetes and renal function on lipid metabolism. We analyzed lipid profiles of PA patients and compared them to propensity-score (PS)-matched essential hypertension (EH) patients adjusting for glycemic status and renal function.
Methods:
Patients who were diagnosed with PA using a saline-infusion test at Seoul National University Hospital from 2000 to 2018 were retrospectively analyzed. EH patients who had aldosterone-renin ratio (ARR) results were selected as controls. Covariates, including diabetes, were PS-matched for patients with PA, lateralized PA, non-lateralized PA, and high ARR to EH patients, respectively.
Results:
Among a total of 80 PA and 80 EH patients, total cholesterol (TC) and triglyceride (TG) levels were significantly lower in the PA patients than in the EH patients (least-squares mean±standard error: 185.5±4.4 mg/dL vs. 196.2±4.4 mg/dL, P=0.047, for TC; and 132.3±11.5 mg/dL vs. 157.4±11.4 mg/dL, P=0.035, for TG) in fully adjusted model (adjusting for multiple covariates, including diabetes status, glycosylated hemoglobin level, and estimated glomerular filtration rate). There were no significant differences in high-density lipoprotein cholesterol (HDL-C) and low-density lipoprotein cholesterol levels between the two groups. According to increments in aldosterone levels, an increasing tendency of HDL-C and decreasing tendencies of TG and non-HDL-C were observed.
Conclusion
PA patients had lower TC and TG levels than EH patients, independent of glycemic status and renal function.
7.Lipid Profiles in Primary Aldosteronism Compared with Essential Hypertension: Propensity-Score Matching Study
Sun Joon MOON ; Han Na JANG ; Jung Hee KIM ; Min Kyong MOON
Endocrinology and Metabolism 2021;36(4):885-894
Background:
There has been controversy regarding the association between primary aldosteronism (PA) and dyslipidemia and few studies considered the effects of diabetes and renal function on lipid metabolism. We analyzed lipid profiles of PA patients and compared them to propensity-score (PS)-matched essential hypertension (EH) patients adjusting for glycemic status and renal function.
Methods:
Patients who were diagnosed with PA using a saline-infusion test at Seoul National University Hospital from 2000 to 2018 were retrospectively analyzed. EH patients who had aldosterone-renin ratio (ARR) results were selected as controls. Covariates, including diabetes, were PS-matched for patients with PA, lateralized PA, non-lateralized PA, and high ARR to EH patients, respectively.
Results:
Among a total of 80 PA and 80 EH patients, total cholesterol (TC) and triglyceride (TG) levels were significantly lower in the PA patients than in the EH patients (least-squares mean±standard error: 185.5±4.4 mg/dL vs. 196.2±4.4 mg/dL, P=0.047, for TC; and 132.3±11.5 mg/dL vs. 157.4±11.4 mg/dL, P=0.035, for TG) in fully adjusted model (adjusting for multiple covariates, including diabetes status, glycosylated hemoglobin level, and estimated glomerular filtration rate). There were no significant differences in high-density lipoprotein cholesterol (HDL-C) and low-density lipoprotein cholesterol levels between the two groups. According to increments in aldosterone levels, an increasing tendency of HDL-C and decreasing tendencies of TG and non-HDL-C were observed.
Conclusion
PA patients had lower TC and TG levels than EH patients, independent of glycemic status and renal function.
8.Therapeutic Barbiturate Coma in Uncontrolled Intracranial Hypertension : Management of Patients and Effect on Outcome.
Chun Kun PARK ; Jang Hoe WHANG ; Dal Soo KIM ; Sang Won LEE ; Moon Chan KIM ; Joon Ki KANG
Journal of Korean Neurosurgical Society 1986;15(3):381-394
In spite of high-dose, hyperventilation, hyperosmolar agents, appropriate surgical evacuation, and cerebrospinal fluid when possible, uncontrolled intracranial hypertension, which was defined as occurring when intracranial pressure(ICP) exceeded 25 mmHg for 2 hours or more, occurred in 8 patients. Persistent elevated ICP occurred in 4 patient with acute subdural hematoma and brain contusion, in 2 patients with aneurysm and brain infarction, in 1 patient with hypertensive intracerebral hematoma, and in 1 patient with meningioma. All of these patients received intravenous barbiturate to control the ICP. The initial thiopental loading dose(10mg/kg) effectively reduced the ICP in 5 patients(62.5%). In those patients responding to the initial loading dose, four have survived, and one died due to pulmonary complication. None of three nonresponders to barbiturate survived. Two of the survivors have returned to a productive life, and two ramain moderately disabled. The favorable outcome in this series suggests that early aggresive treatment of intracranial hypertension with barbiturate and careful attention to medical complications can improve the outcome in patients with uncontrolled intracranial hypertension, with barbiturate and careful attention to medical complications can improve the outcome in patients with uncontrolled intracranial hypertension, especially in postoperative state. A broader investigation of the clinical application of barbiturates in indicated.
Aneurysm
;
Barbiturates
;
Brain Infarction
;
Brain Injuries
;
Cerebrospinal Fluid
;
Coma*
;
Hematoma
;
Hematoma, Subdural, Acute
;
Humans
;
Hyperventilation
;
Intracranial Hypertension*
;
Meningioma
;
Survivors
;
Thiopental
9.An in-vitro evaluation of sealer placement methods in simulated root canal extensions.
Sung Young KIM ; Mi Jeong LEE ; Jang Won MOON ; Se Joon LEE ; Mi Kyung YU
Journal of Korean Academy of Conservative Dentistry 2005;30(1):31-37
The aim of this study was to evaluate the effectiveness of sealer placement in simulated root canal extensions. Forty resin blocks were attained from the Endo-training Bloc. In each block, the simulated root canal was made with #20, 08taper GT file. After each block was longitudinally split into two halves, a standardized groove was prepared on one canal wall of two halves to simulate the canal extensions with various irregularities. The two halves of each block were assembled and all simulated root canals were obturated by single cone method with AH26 sealer. Four different methods of sealer placement were used: group A, #20 K-file; group B, ultrasonic file; group C, lentulo spiral; group D, EZ-Fill bi-directional spiral. All obturated blocks were stored in 100% humidity at 37degrees C for 1 week. Using a low speed saw, each block was sectioned horizontally. Images of the sections were taken using a stereomicroscope at x 30 magnification and a digital camera. The amount of the sealer in the groove was evaluated using a scoring system, a higher score indicated better sealing effectiveness. The data was statistically analysed by Fisher's Exact Test. The sealing score was the lowest, specially at the middle area of canal extensions in group A, and that was statistically significant difference from other groups. In conclusion, the ultrasonic file, lentulo spiral and EZ-Fill bi-directional spiral were effective methods of sealer placement in simulated canal extensions. The K file was the least effective method, specially at the middle area of canal extensions.
Dental Pulp Cavity*
;
Humidity
;
Ultrasonics
10.Analysis for Failure and Immediate Complications of Subclavian Venous Catheterization.
Won Joon CHO ; Moon Key JANG ; Seung Cheol LEE ; Young Jhoon CHIN ; Chan Jong CHUNG
Anesthesia and Pain Medicine 2008;3(2):149-153
BACKGROUND: This study was to investigate success rate, immediate complications, and risk factors of failure and immediate complications of subclavian venous catheterization (SVC). METHODS: All patients requiring SVC, older than 18 years of age and without past history of operation, scar, and radiation therapy at puncture site were included. After general or regional anesthesia was induced, SVC was done via infraclavicular approach. Patient's age, gender, weight, height, the rank of operator, anesthesia method, the side of venipuncture, the number of puncture attempts, arterial puncture, and success or failure were recorded. After the operation, a chest radiography was evaluated to check the occurrence of pneumothorax, hemothorax and the location of the catheter tip. RESULTS: SVC was performed in 1092 patients. Thirty-nine patients were excluded because a chest radiography was not checked. Successful catheterization without immediate complications was performed in 939 patients (89.2%). Failure occurred in 65 patients (6.2%). Arterial puncture, pneumothorax and misplacement of the catheter tip were reported in 26 (2.5%), 5 (0.5%), and 35 (3.3%) patients, respectively. Misplacement of the catheter tip were observed in 26 patients (2.5%) at ipsilateral internal jugular vein, and in 9 (0.8%) at contralateral subclavian vein. Failure and immediate complications of SVC were associated with the number of puncture attempts. The number of puncture attempts were associated with age, puncture side and anesthetic method. CONCLUSIONS: Failure and immediate complications of SVC occurred in 10.8% of cases and were associated with the number of puncture attempts.
Anesthesia
;
Anesthesia, Conduction
;
Catheterization
;
Catheterization, Central Venous
;
Catheters
;
Cicatrix
;
Hemothorax
;
Humans
;
Jugular Veins
;
Phlebotomy
;
Pneumothorax
;
Punctures
;
Risk Factors
;
Subclavian Vein
;
Thorax